PIMA515632

JAK2 Monoclonal Antibody (1C1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515632-Each-of-1 In Stock ₹ 50,694.30

PIMA515632 - Each of 1

₹ 50,694.30

In Stock

Quantity

1

Base Price: ₹ 50,694.30

GST (18%): ₹ 9,124.974

Total Price: ₹ 59,819.274

Antigen

JAK2

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

1C1

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15632 targets JAK2 in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15632 immunogen is purified recombinant fragment of JAK2(745-955aa) expressed in E
  • Coli.<br>
  • MA5-15632 detects JAK2 which has a predicted molecular weight of approximately 130.6kDa
  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515632

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Antigen:
JAK2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1C1

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515633

--


Antigen:
N-cadherin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P15116, P19022, Q9Z1Y3

Gene Symbols:
CDH2

Immunogen:
Purified recombinant fragment of human CDH2 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
1000, 12558, 83501

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5D5

Conjugate:
Unconjugated

Gene:
CDH2

Gene Alias:
bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515634

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Antigen:
ETK

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P51813

Gene Symbols:
BMX

Immunogen:
Purified recombinant fragment of human BMX expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
660

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1C6

Conjugate:
Unconjugated

Gene:
BMX

Gene Alias:
BMX; BMX non-receptor tyrosine kinase; bone marrow tyrosine kinase gene in chromosome X protein; Bone marrow tyrosine kinase gene in chromosome X protein homolog; BTK-like on X chromosome; cytoplasmic tyrosine-protein kinase BMX; epa3; Epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx; Etk/Bmx cytosolic tyrosine kinase; NTK38; NTK38 tyrosine kinase; PSCTK2; PSCTK3; RGD1565643; Tyro8; TYRO8 protein tyrosine kinase 8

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515635

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Antigen:
p27 Kip1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P46527

Gene Symbols:
Cdkn1b

Immunogen:
Purified recombinant fragment of human CDKN1B expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
1027

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
3D8

Conjugate:
Unconjugated

Gene:
Cdkn1b

Gene Alias:
AA408329; AI843786; Cdki1b; CDKN1B; CDKN4; CDN1B; cyclin dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B (p27 Kip1); Cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor p27 Kip1; cyclin-dependent kinase inhibitor p27/Kip1; KIP1; MEN1B; MEN4; p27; P27 CDKN1B; p27(KIP1); p27Kip1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1