PIMA515585

USP7 Monoclonal Antibody (5F11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515585-Each-of-1 In Stock ₹ 53,218.32

PIMA515585 - Each of 1

₹ 53,218.32

In Stock

Quantity

1

Base Price: ₹ 53,218.32

GST (18%): ₹ 9,579.298

Total Price: ₹ 62,797.618

Antigen

USP7

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q93009

Gene Symbols

USP7

Immunogen

Purified recombinant fragment of human HAUSP expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

7874

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

5F11

Conjugate

Unconjugated

Gene

USP7

Gene Alias

2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15585 targets HAUSP in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15585 immunogen is purified recombinant fragment of human HAUSP expressed in E
  • Coli
  • MA5-15585 detects HAUSP which has a predicted molecular weight of approximately 128kDa
  • USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
  • Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP activity generally stabilizes its substrate proteins
  • HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53
  • Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
  • Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
  • Another important role of HAUSP function involves the oncogenic stabilization of p53
  • Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
  • An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.

Compare Similar Items

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Img

Thermo Scientific

PIMA515585

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Antigen:
USP7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q93009

Gene Symbols:
USP7

Immunogen:
Purified recombinant fragment of human HAUSP expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
7874

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
5F11

Conjugate:
Unconjugated

Gene:
USP7

Gene Alias:
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

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PIMA515587

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Antigen:
RAB25

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P57735, Q9WTL2

Gene Symbols:
RAB25

Immunogen:
Purified recombinant fragment of Rab25 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
53868, 57111

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3F12

Conjugate:
Unconjugated

Gene:
RAB25

Gene Alias:
AV012978; CATX8; CATX-8; RAB11C; RAB25; RAB25, member RAS oncogene family; ras-related protein Rab-25

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

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PIMA515588

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Antigen:
FAK

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P34152, Q05397

Gene Symbols:
PTK2

Immunogen:
Purified recombinant fragment of human FAK expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
14083, 5747

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
10H7

Conjugate:
Unconjugated

Gene:
PTK2

Gene Alias:
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515589

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Antigen:
PP1 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P62136, P62137

Gene Symbols:
PPP1CA

Immunogen:
Purified recombinant fragment of human PPP1A expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
19045, 5499

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
6D1

Conjugate:
Unconjugated

Gene:
PPP1CA

Gene Alias:
96A; CG6593; CG6593-PA; CG6593-PB; dism2; Dmel\CG6593; Dmel_CG6593; DmPp1-96A; GADD34; LD14639p; MGC15877; MGC1674; PP1; PP1 96A; PP1 alpha96a; Pp1-96A; PP1A; PP-1A; PP1A-96A; PP1alpha; PP1alpha[[1]]; PP1alpha96A; pp1alpha-96A; Pp1alpha-96A-PA; Pp1alpha-96A-PB; PP1c; PP1c 96A; PPP1A; Ppp1c; Ppp1ca; protein phosphatase 1; protein phosphatase 1 catalytic subunit alpha; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase 1alpha at 96A; protein phosphatase type 1 alpha catalytic subunit; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase alpha-1 isoform; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1