PIMA515682
SMAD4 Monoclonal Antibody (4G1C6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515682-Each-of-1 | In Stock | ₹ 50,523.18 |
PIMA515682 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,523.18
GST (18%): ₹ 9,094.172
Total Price: ₹ 59,617.352
Antigen
SMAD4
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P97471, Q13485
Gene Symbols
SMAD4
Immunogen
Purified recombinant fragment of human SMAD4 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
17128, 4089
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
4G1C6
Conjugate
Unconjugated
Gene
SMAD4
Gene Alias
AW743858; D18Wsu70e; Deleted in Pancreatic Carcinoma 4 (DPC4); deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; DPC4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MAD homolog 4 (MADH4); Madh4; mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4 (MADH4); mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15682 targets SMAD4 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples
- The MA5-15682 immunogen is purified recombinant fragment of human SMAD4 expressed in E
- Coli
- MA5-15682 detects SMAD4 which has a predicted molecular weight of approximately 65kDa
- Smad4 is encoded by the Smad4 gene that is located on chromosome 18 in humans
- Smad4 is also known as Smad family member 4, Sma- and Mad-related protein 4 or Mothers against decapentaplegic (MAD) homolog 4
- Smad4 contains N-terminal MH1 (MAD homology 1) and C-terminal MH2 (MAD homology 2) globular domains that are involved in DNA binding and protein interactions respectively
- Binding of the TGF-beta superfamily of ligands that includes Transforming Growth Factor -beta (TGF-beta) and bone morphogenetic protein (BMP) to its cognate receptor allows phosphorylation of Smad 1, 2, 3, 5 and 8 (R-Smad, Receptor Smad)
- This signals for heterotrimerization with Smad4 (co-Smad, co-mediator Smad) and translocation of the complex to the nucleus
- Inhibitory or antagonistic Smad (I-Smad) that includes Smad 6 and 7, interact with activated R-Smads and attenuate the signaling pathway
- Smad4 acts as a tumor suppressor protein by transcriptionally regulating its target genes such as Cyclin D1 (downregulation) and collagen (upregulation) that inhibit cell proliferation
- Dephosphorylation regulates nuclear export and nucleocytoplasmic dynamics of Smads.
Compare Similar Items
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Antigen: SMAD4
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P97471, Q13485
Gene Symbols: SMAD4
Immunogen: Purified recombinant fragment of human SMAD4 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 17128, 4089
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 4G1C6
Conjugate: Unconjugated
Gene: SMAD4
Gene Alias: AW743858; D18Wsu70e; Deleted in Pancreatic Carcinoma 4 (DPC4); deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; DPC4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MAD homolog 4 (MADH4); Madh4; mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4 (MADH4); mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Antigen:
SMAD4
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P97471, Q13485
Gene Symbols:
SMAD4
Immunogen:
Purified recombinant fragment of human SMAD4 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
17128, 4089
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
4G1C6
Conjugate:
Unconjugated
Gene:
SMAD4
Gene Alias:
AW743858; D18Wsu70e; Deleted in Pancreatic Carcinoma 4 (DPC4); deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; DPC4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MAD homolog 4 (MADH4); Madh4; mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4 (MADH4); mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Antigen: RICTOR
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q6QI06, Q6R327
Gene Symbols: Rictor
Immunogen: Purified recombinant fragment of human RICTOR expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 253260, 78757
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Western Blot
Clone: 4H5
Conjugate: Unconjugated
Gene: Rictor
Gene Alias: 4921505C17Rik; 6030405M08Rik; AVO3; AVO3 homolog; AW492497; D530039E11Rik; DKFZp686B11164; Fyb; FYN binding protein; hAVO3; Kiaa1999; mAVO3; MGC39830; PIA; pianissimo; protein pianissimo; Rapamycin-insensitive companion of mTOR; rictor; RPTOR independent companion of MTOR complex 2; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG1
Antigen:
RICTOR
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q6QI06, Q6R327
Gene Symbols:
Rictor
Immunogen:
Purified recombinant fragment of human RICTOR expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
253260, 78757
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
4H5
Conjugate:
Unconjugated
Gene:
Rictor
Gene Alias:
4921505C17Rik; 6030405M08Rik; AVO3; AVO3 homolog; AW492497; D530039E11Rik; DKFZp686B11164; Fyb; FYN binding protein; hAVO3; Kiaa1999; mAVO3; MGC39830; PIA; pianissimo; protein pianissimo; Rapamycin-insensitive companion of mTOR; rictor; RPTOR independent companion of MTOR complex 2; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1
Antigen: Epo
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P01588
Gene Symbols: EPO
Immunogen: Purified recombinant fragment of human EPO expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 2056
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 4F11
Conjugate: Unconjugated
Gene: EPO
Gene Alias: EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Epo
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P01588
Gene Symbols:
EPO
Immunogen:
Purified recombinant fragment of human EPO expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
2056
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
4F11
Conjugate:
Unconjugated
Gene:
EPO
Gene Alias:
EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: UBE1L
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P41226
Gene Symbols: UBA7
Immunogen: Purified recombinant fragment of human UBE1L expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 7318
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Western Blot
Clone: 5B10
Conjugate: Unconjugated
Gene: UBA7
Gene Alias: 1300004C08Rik; D8; MGC12713; UBA1, ubiquitin-activating enzyme E1 homolog B; UBA1B; UBA7; UBA7, ubiquitin-activating enzyme E1; UBE1L; UBE2; ubiquitin like modifier activating enzyme 7; ubiquitin-activating enzyme 7; Ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1-related protein; ubiquitin-activating enzyme-2; ubiquitin-like modifier activating enzyme 7; ubiquitin-like modifier-activating enzyme 7
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
UBE1L
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P41226
Gene Symbols:
UBA7
Immunogen:
Purified recombinant fragment of human UBE1L expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
7318
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
5B10
Conjugate:
Unconjugated
Gene:
UBA7
Gene Alias:
1300004C08Rik; D8; MGC12713; UBA1, ubiquitin-activating enzyme E1 homolog B; UBA1B; UBA7; UBA7, ubiquitin-activating enzyme E1; UBE1L; UBE2; ubiquitin like modifier activating enzyme 7; ubiquitin-activating enzyme 7; Ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1-related protein; ubiquitin-activating enzyme-2; ubiquitin-like modifier activating enzyme 7; ubiquitin-like modifier-activating enzyme 7
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1