PIMA515122
Phospho-SMAD2 (Ser465, Ser467) Monoclonal Antibody (138D4), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515122-Each-of-1 | In Stock | ₹ 53,303.88 |
PIMA515122 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,303.88
GST (18%): ₹ 9,594.698
Total Price: ₹ 62,898.578
Antigen
Phospho-SMAD2 (Ser465, Ser467)
Classification
Monoclonal
Concentration
149 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
O70436, Q15796, Q62432
Gene Symbols
SMAD2
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding pSer465/467 of human Smad2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mink, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
138D4
Conjugate
Unconjugated
Gene
SMAD2
Gene Alias
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17126, 29357, 4087
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with other Smad-related proteins
- SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
- Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
- In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.
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Antigen: Phospho-SMAD2 (Ser465, Ser467)
Classification: Monoclonal
Concentration: 149 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: O70436, Q15796, Q62432
Gene Symbols: SMAD2
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer465/467 of human Smad2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mink, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 138D4
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17126, 29357, 4087
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-SMAD2 (Ser465, Ser467)
Classification:
Monoclonal
Concentration:
149 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
O70436, Q15796, Q62432
Gene Symbols:
SMAD2
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer465/467 of human Smad2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mink, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
138D4
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17126, 29357, 4087
Content And Storage:
-20°C
Form:
Liquid
Antigen: S6
Classification: Monoclonal
Concentration: 4 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P29327, P62753, P62754, P62755
Gene Symbols: RPS6
Immunogen: Recombinant fusion protein corresponding to full-length human S6 ribosomal protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: C.896.4
Conjugate: Unconjugated
Gene: RPS6
Gene Alias: (Rp)S6; 40S ribosomal protein S6; air[8]; air8; anon-WO02059370.61; CG10944; CG10944-PA; CG10944-PB; Dmel\CG10944; Dmel_CG10944; DS6; hemocytes enlarged; hen; l(1)air[8]; l(1)air8; l(1)hen; LD31286p; lethal(1)aberrant immune response[8]; lethal-(1)-haemocytes enlarged; lethal-aberrant-immune-response-8; M(1)7BC; M(1)7C; minute; minute (1) 7BC; OK/SW-cl.2; OTTHUMP00000021121; OTTHUMP00000021122; Phosphoprotein NP33; pp30; ribosomal protein S6; Rp S6; RP11-513M16.6; RPS6; RpS6-PA; RpS6-PB; RS6; S6; S6 ribosomal protein; S6R; Small ribosomal subunit protein eS6; wu:fa92e06; wu:fb64g06; zgc:92237
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20104, 29304, 31700, 6194
Content And Storage: -20°C
Form: Liquid
Antigen:
S6
Classification:
Monoclonal
Concentration:
4 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P29327, P62753, P62754, P62755
Gene Symbols:
RPS6
Immunogen:
Recombinant fusion protein corresponding to full-length human S6 ribosomal protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
C.896.4
Conjugate:
Unconjugated
Gene:
RPS6
Gene Alias:
(Rp)S6; 40S ribosomal protein S6; air[8]; air8; anon-WO02059370.61; CG10944; CG10944-PA; CG10944-PB; Dmel\CG10944; Dmel_CG10944; DS6; hemocytes enlarged; hen; l(1)air[8]; l(1)air8; l(1)hen; LD31286p; lethal(1)aberrant immune response[8]; lethal-(1)-haemocytes enlarged; lethal-aberrant-immune-response-8; M(1)7BC; M(1)7C; minute; minute (1) 7BC; OK/SW-cl.2; OTTHUMP00000021121; OTTHUMP00000021122; Phosphoprotein NP33; pp30; ribosomal protein S6; Rp S6; RP11-513M16.6; RPS6; RpS6-PA; RpS6-PB; RS6; S6; S6 ribosomal protein; S6R; Small ribosomal subunit protein eS6; wu:fa92e06; wu:fb64g06; zgc:92237
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20104, 29304, 31700, 6194
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-SMAD1/SMAD5 (Ser463, Ser465)
Classification: Monoclonal
Concentration: 148 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P70340, P97454, P97588, Q15797, Q99717, Q9R1V3
Gene Symbols: SMAD1, Smad5
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer463/465 of human Smad5
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: E.239.4
Conjugate: Unconjugated
Gene: SMAD1
Gene Alias: 1110051M15Rik; AI451355; AI528653; BSP1; BSP-1; dwarfin-A; Dwarfin-C; dwf-A; DWFC; Dwf-C; hSMAD1; hSmad5; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog 5; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; MAD, mothers against decapentaplegic homolog 5; Madh1; Madh5; Madr1; mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 1; mothers against DPP homolog 5; mothers-against-DPP-related 1; Msmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; Smad 1; SMAD 5; SMAD family member 1; SMAD family member 5; SMAD, mothers against DPP homolog 1; SMAD, mothers against DPP homolog 5; SMAD1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17125, 17129, 25671, 4086, 4090, 59328
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-SMAD1/SMAD5 (Ser463, Ser465)
Classification:
Monoclonal
Concentration:
148 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P70340, P97454, P97588, Q15797, Q99717, Q9R1V3
Gene Symbols:
SMAD1, Smad5
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer463/465 of human Smad5
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
E.239.4
Conjugate:
Unconjugated
Gene:
SMAD1
Gene Alias:
1110051M15Rik; AI451355; AI528653; BSP1; BSP-1; dwarfin-A; Dwarfin-C; dwf-A; DWFC; Dwf-C; hSMAD1; hSmad5; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog 5; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; MAD, mothers against decapentaplegic homolog 5; Madh1; Madh5; Madr1; mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 1; mothers against DPP homolog 5; mothers-against-DPP-related 1; Msmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; Smad 1; SMAD 5; SMAD family member 1; SMAD family member 5; SMAD, mothers against DPP homolog 1; SMAD, mothers against DPP homolog 5; SMAD1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17125, 17129, 25671, 4086, 4090, 59328
Content And Storage:
-20°C
Form:
Liquid
Antigen: STAT1
Classification: Monoclonal
Concentration: 167 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P42224
Gene Symbols: STAT1
Immunogen: Synthetic peptide corresponding to the sequence of human Stat1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: C.156.9
Conjugate: Unconjugated
Gene: STAT1
Gene Alias: 2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6772
Content And Storage: -20°C
Form: Liquid
Antigen:
STAT1
Classification:
Monoclonal
Concentration:
167 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P42224
Gene Symbols:
STAT1
Immunogen:
Synthetic peptide corresponding to the sequence of human Stat1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
C.156.9
Conjugate:
Unconjugated
Gene:
STAT1
Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6772
Content And Storage:
-20°C
Form:
Liquid