PIMA515706

Cyclin B1 Monoclonal Antibody (1B10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515706-Each-of-1 In Stock ₹ 48,213.06

PIMA515706 - Each of 1

₹ 48,213.06

In Stock

Quantity

1

Base Price: ₹ 48,213.06

GST (18%): ₹ 8,678.351

Total Price: ₹ 56,891.411

Antigen

Cyclin B1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P14635, P30277

Gene Symbols

Ccnb1

Immunogen

Purified recombinant fragment of human CCNB1 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

25203, 891

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

1B10

Conjugate

Unconjugated

Gene

Ccnb1

Gene Alias

Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15706 targets CCNB1 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
  • The MA5-15706 immunogen is purified recombinant fragment of human CCNB1 expressed in E
  • Coli
  • MA5-15706 detects CCNB1 which has a predicted molecular weight of approximately 60kDa
  • Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs)
  • Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis
  • It is essential for the control of the cell cycle at the G2/M transition
  • Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)
  • Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase
  • Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis
  • Destruction of Cyclin B1 is required for cell cycle progression
  • Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515706

--


Antigen:
Cyclin B1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P14635, P30277

Gene Symbols:
Ccnb1

Immunogen:
Purified recombinant fragment of human CCNB1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
25203, 891

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
1B10

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515707

--


Antigen:
CSK

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P32577, P41240, P41241

Gene Symbols:
CSK

Immunogen:
Purified recombinant fragment of human CSK expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
12988, 1445, 315707

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
5F3

Conjugate:
Unconjugated

Gene:
CSK

Gene Alias:
AW212630; CSK; CSK, non-receptor tyrosine kinase; C-SRC kinase; c-src tyrosine kinase; C-terminal Src kinase; MGC117393; p50CSK; protein-tyrosine kinase (CSK); protein-tyrosine kinase CYL; Protein-tyrosine kinase MPK-2; Tyrosine-protein kinase CSK

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515708

--


Antigen:
PAX8

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q06710

Gene Symbols:
PAX8

Immunogen:
Purified recombinant fragment of human PAX8 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
7849

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
2D4

Conjugate:
Unconjugated

Gene:
PAX8

Gene Alias:
HGNC:8622; paired box 8; paired box gene 8; paired box protein Pax-8; paired domain gene 8; PAX8; Pax-8; Pax-8 protein

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515710

--


Antigen:
Torc2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q53ET0

Gene Symbols:
CRTC2

Immunogen:
Purified recombinant fragment of human CRTC2 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
200186

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5B10

Conjugate:
Unconjugated

Gene:
CRTC2

Gene Alias:
4632407F12Rik; CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; CRTC2; mTORC2; OTTHUMP00000035255; RGD1308903; TORC2; TORC-2; transducer of CREB protein 2; transducer of regulated cAMP response element-binding protein (CREB) 2; transducer of regulated cAMP response element-binding protein 2

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1