PIMA514327

Cyclin B1 Monoclonal Antibody (GNS11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514327-Each-of-1 In Stock ₹ 51,250.44

PIMA514327 - Each of 1

₹ 51,250.44

In Stock

Quantity

1

Base Price: ₹ 51,250.44

GST (18%): ₹ 9,225.079

Total Price: ₹ 60,475.519

Antigen

Cyclin B1

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P14635, P24860, P30277, Q08301

Gene Symbols

Ccnb1

Immunogen

Human cyclin B1 protein

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

GNS11

Conjugate

Unconjugated

Gene

Ccnb1

Gene Alias

Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100770842, 25203, 268697, 891

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-14327 targets Cyclin B1 in WB, ICC/IF, IHC (P), and IP applications and shows reactivity with Hamster, Human, mouse, and Rat samples
  • This antibody is not recommended for NIH-3T3 cells in Western blot applications
  • The MA5-14327 immunogen is human cyclin B1 protein
  • This antibody was orginally validated as part of a Thermo Scientific Cellomics High Content Screening Kit
  • The antibody sold separately may have slightly different performance and may need to be further optimized for the best results
  • Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs)
  • Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis
  • It is essential for the control of the cell cycle at the G2/M transition
  • Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)
  • Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase
  • Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis
  • Destruction of Cyclin B1 is required for cell cycle progression
  • Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA514327

--


Antigen:
Cyclin B1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P14635, P24860, P30277, Q08301

Gene Symbols:
Ccnb1

Immunogen:
Human cyclin B1 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
GNS11

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100770842, 25203, 268697, 891

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514344

--


Antigen:
E2F1

Classification:
Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q01094, Q61501

Gene Symbols:
E2F1

Immunogen:
Recombinant human E2F-1 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
KH95

Conjugate:
Unconjugated

Gene:
E2F1

Gene Alias:
E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13555, 1869

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514361

--


Antigen:
p57 Kip2

Classification:
Monoclonal

Concentration:
0.05 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P49918, P49919

Gene Symbols:
CDKN1C

Immunogen:
Recombinant human p57Kip2 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
KP39

Conjugate:
Unconjugated

Gene:
CDKN1C

Gene Alias:
AL024410; Beckwith Wiedemann syndrome (WBS); BWCR; BWS; CDKI; Cdkn1c; cyclin dependent kinase inhibitor 1C; Cyclin dependent kinase inhibitor 1C (CDKN1C); cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (P57); cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; IMAGE; KIP2; p57; p57 Kip2; p57(kip2); p57KIP2; p57KIP2 A3sh; WBS

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1028, 12577

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514366

--


Antigen:
Cdk5

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P49615, Q00535, Q03114

Gene Symbols:
CDK5

Immunogen:
Recombinant cdk5 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
__

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
DC34

Conjugate:
Unconjugated

Gene:
CDK5

Gene Alias:
AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1020, 12568, 140908

Content And Storage:
4° C

Form:
Liquid