PIMA516082

CIP2A Monoclonal Antibody (2G10), DyLight™ 488, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516082-Each-of-1 In Stock ₹ 47,956.38

PIMA516082 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

CIP2A

Classification

Monoclonal

Concentration

1.1 mg/mL

Formulation

50mM sodium borate with 0.05% sodium azide

Gene Accession No.

Q8BWY9, Q8TCG1

Gene Symbols

Cip2a

Immunogen

A C-terminal portion of the human p90 protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG2b κ

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

2G10

Conjugate

DyLight 488

Gene

Cip2a

Gene Alias

AA408511; AU018569; C330027C09Rik; Cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; Cip2a; Kiaa1524; p90; p90 autoantigen; p90 autoantigen homolog; Protein CIP2A; RGD1310335; RIKEN cDNA C330027C09 gene; similar to RIKEN cDNA C330027C09

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

224171, 360711, 57650

Content And Storage

4° C, store in dark

Form

Liquid

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Description

  • Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells
  • The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation
  • In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation
  • The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A
  • Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA516082

--


Antigen:
CIP2A

Classification:
Monoclonal

Concentration:
1.1 mg/mL

Formulation:
50mM sodium borate with 0.05% sodium azide

Gene Accession No.:
Q8BWY9, Q8TCG1

Gene Symbols:
Cip2a

Immunogen:
A C-terminal portion of the human p90 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2G10

Conjugate:
DyLight 488

Gene:
Cip2a

Gene Alias:
AA408511; AU018569; C330027C09Rik; Cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; Cip2a; Kiaa1524; p90; p90 autoantigen; p90 autoantigen homolog; Protein CIP2A; RGD1310335; RIKEN cDNA C330027C09 gene; similar to RIKEN cDNA C330027C09

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
224171, 360711, 57650

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA516083

--


Antigen:
CIP2A

Classification:
Monoclonal

Concentration:
1.8 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q8BWY9, Q8TCG1

Gene Symbols:
Cip2a

Immunogen:
A C-terminal portion of the human p90 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
2G10

Conjugate:
HRP

Gene:
Cip2a

Gene Alias:
AA408511; AU018569; C330027C09Rik; Cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; Cip2a; Kiaa1524; p90; p90 autoantigen; p90 autoantigen homolog; Protein CIP2A; RGD1310335; RIKEN cDNA C330027C09 gene; similar to RIKEN cDNA C330027C09

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
224171, 360711, 57650

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA516084

--


Antigen:
CIP2A

Classification:
Monoclonal

Concentration:
1.8 mg/mL

Formulation:
50mM sodium borate with no preservative

Gene Accession No.:
Q8BWY9, Q8TCG1

Gene Symbols:
Cip2a

Immunogen:
A C-terminal portion of the human p90 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2G10

Conjugate:
DyLight 550

Gene:
Cip2a

Gene Alias:
AA408511; AU018569; C330027C09Rik; Cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; Cip2a; Kiaa1524; p90; p90 autoantigen; p90 autoantigen homolog; Protein CIP2A; RGD1310335; RIKEN cDNA C330027C09 gene; similar to RIKEN cDNA C330027C09

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
224171, 360711, 57650

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA516085

--


Antigen:
NAPSA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Synthetic peptide corresponding to the N-terminus of human NAPSIN1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
TMU-Ad02

Conjugate:
Unconjugated

Gene:
NAPSA

Gene Alias:
asp 4; ASP4; Aspartyl protease 4; KAP; Kdap; KDAP-1; kidney-derived aspartic protease-like protein; Nap; NAP1; NAPA; Napsa; napsin A aspartic peptidase; napsin-1; Napsin-A; pronapsin; pronapsin A; SNAPA; TA01/TA02

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9476

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid