PIMA516084

CIP2A Monoclonal Antibody (2G10), DyLight™ 550, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA516084-Each-of-1 In Stock ₹ 45,731.82

PIMA516084 - Each of 1

₹ 45,731.82

In Stock

Quantity

1

Base Price: ₹ 45,731.82

GST (18%): ₹ 8,231.728

Total Price: ₹ 53,963.548

Antigen

CIP2A

Classification

Monoclonal

Concentration

1.8 mg/mL

Formulation

50mM sodium borate with no preservative

Gene Accession No.

Q8BWY9, Q8TCG1

Gene Symbols

Cip2a

Immunogen

A C-terminal portion of the human p90 protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG2b κ

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

2G10

Conjugate

DyLight 550

Gene

Cip2a

Gene Alias

AA408511; AU018569; C330027C09Rik; Cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; Cip2a; Kiaa1524; p90; p90 autoantigen; p90 autoantigen homolog; Protein CIP2A; RGD1310335; RIKEN cDNA C330027C09 gene; similar to RIKEN cDNA C330027C09

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

224171, 360711, 57650

Content And Storage

4° C, store in dark

Form

Liquid

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Description

  • Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells
  • The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation
  • In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation
  • The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A
  • Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA516084

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Antigen:
CIP2A

Classification:
Monoclonal

Concentration:
1.8 mg/mL

Formulation:
50mM sodium borate with no preservative

Gene Accession No.:
Q8BWY9, Q8TCG1

Gene Symbols:
Cip2a

Immunogen:
A C-terminal portion of the human p90 protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2G10

Conjugate:
DyLight 550

Gene:
Cip2a

Gene Alias:
AA408511; AU018569; C330027C09Rik; Cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; Cip2a; Kiaa1524; p90; p90 autoantigen; p90 autoantigen homolog; Protein CIP2A; RGD1310335; RIKEN cDNA C330027C09 gene; similar to RIKEN cDNA C330027C09

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
224171, 360711, 57650

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA516085

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Antigen:
NAPSA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
tris glycine with 0.15M NaCl and 0.05% sodium azide

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Synthetic peptide corresponding to the N-terminus of human NAPSIN1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
TMU-Ad02

Conjugate:
Unconjugated

Gene:
NAPSA

Gene Alias:
asp 4; ASP4; Aspartyl protease 4; KAP; Kdap; KDAP-1; kidney-derived aspartic protease-like protein; Nap; NAP1; NAPA; Napsa; napsin A aspartic peptidase; napsin-1; Napsin-A; pronapsin; pronapsin A; SNAPA; TA01/TA02

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9476

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516086

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Antigen:
Tenascin C

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P24821, Q80YX1

Gene Symbols:
TNC

Immunogen:
Recombinant human Tenascin C.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Feline, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
4C8MS

Conjugate:
Unconjugated

Gene:
TNC

Gene Alias:
150-225; AI528729; C130033P17Rik; cytotactin; deafness, autosomal dominant 56; DFNA56; Glioma-associated-extracellular matrix antigen; GMEM; GP; GP 150-225; hexabrachion; hexabrachion (tenascin); Hxb; JI; MGC144208; MGC144209; MGC167029; Myotendinous antigen; neuronectin; Ten; Tenascin; tenascin C; Tenascin-C; tenascin-C additional domain 1; tenascin-C isoform 14/AD1/16; TN; tnc; TN-C

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
101083629, 116640, 21923, 3371

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516087

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Antigen:
Phospho-NHE3 (Ser605)

Classification:
Monoclonal

Concentration:
0.80 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
G3X939, P26432, P26433

Gene Symbols:
SLC9A3

Immunogen:
Synthetic peptide made to a region surrounding the Serine 605 portion of the rat protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Marsupial, Mouse, Non-human Primate, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Western Blot

Clone:
10A8

Conjugate:
Biotin

Gene:
SLC9A3

Gene Alias:
9030624O13Rik; AI930210; DIAR8; MGC126718; MGC126720; Na(+)/H(+) exchanger 3; Na/H exchanger 3; Na+/H+ exchanger homolog; Na+/H+ exchanger isoform 3; membrane ion exchange protein; Nhe3; NHE-3; NHE-3 antibody; plasma membrane ion transport protein; putative sodium hydrogen exchanger subtype 3; Slc9a3; SLC9A3 antibody; sodium proton exchanger; sodium/hydrogen exchanger; sodium/hydrogen exchanger 3; sodium/hydrogen exchanger isoform 3; Solute carrier family 9 (sodium/hydrogen exchanger 3), antiporter 3, Na+/H+ (amiloride insensitive); solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; solute carrier family 9 (sodium/hydrogen exchanger), member 3; solute carrier family 9 member 3; solute carrier family 9 member A3; solute carrier family 9, member 3; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100009430, 105243, 24784, 397358

Content And Storage:
4° C, store in dark

Form:
Liquid