PIMA516159

TBK1 Monoclonal Antibody (108A429), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516159-Each-of-1 In Stock ₹ 48,555.30

PIMA516159 - Each of 1

₹ 48,555.30

In Stock

Quantity

1

Base Price: ₹ 48,555.30

GST (18%): ₹ 8,739.954

Total Price: ₹ 57,295.254

Antigen

TBK1

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q9UHD2, Q9WUN2

Gene Symbols

TBK1

Immunogen

Synthetic peptide (YYQFKKDKAERRLAYC ) of TBK1/NAK protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

108A429

Conjugate

Unconjugated

Gene

TBK1

Gene Alias

1200008B05Rik; AI462036; AW048562; FLJ11330; FTDALS4; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine protein kinase TBK1; serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1; TANK-binding kinase 1; tbk; TBK1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

29110, 299827, 481145, 533141, 56480

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Suggested positive control: human testis protein, NIH-3T3 or RAW
  • TBK1 serine/threonine kinase is a member of the IKK family and is involved in NF-kappa B activation and IRF3 signaling
  • TBK1 is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses
  • NF-KB mediates the expression of a great variety of genes in response to extracellular stimuli
  • NF-KB is associated with IKB proteins in the cell cytoplasm, which inhibit NF-KB activity
  • Phosphorylation of I-KB by IKB kinase (IKK) complex leads to degradation of I-KB and activation of NF-KB
  • The IKK complex contains IKKa, IKK beta, and IKKK
  • A novel IKK related kinase was recently identified and designated TBK1 (TANK-binding kinase 1), NAK (NF-KB-activating kinase), and T2K
  • NAK/TBK1 activates IKK beta through direct phosphorylation
  • NAK/TBK1 is activated by growth factors and PMA and mediates IKK and NF-kB activation in response to growth factors
  • NAK/TBK1 functions upstream of NIK and the IKK complex
  • NAK/TBK1 is also critical in protecting embryonic liver from apoptosis.

Compare Similar Items

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Img

Thermo Scientific

PIMA516159

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Antigen:
TBK1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9UHD2, Q9WUN2

Gene Symbols:
TBK1

Immunogen:
Synthetic peptide (YYQFKKDKAERRLAYC ) of TBK1/NAK protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
108A429

Conjugate:
Unconjugated

Gene:
TBK1

Gene Alias:
1200008B05Rik; AI462036; AW048562; FLJ11330; FTDALS4; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine protein kinase TBK1; serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1; TANK-binding kinase 1; tbk; TBK1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
29110, 299827, 481145, 533141, 56480

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516161

--


Antigen:
Phospho-IkB alpha (Ser32, Ser36)

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P25963, Q08353, Q63746, Q9Z1E3

Gene Symbols:
NFKBIA

Immunogen:
Synthetic peptide containing phosphorylated serines at amino acid residues 32 and 36 of human IkBa.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunoprecipitation, Western Blot

Clone:
39A1413

Conjugate:
Unconjugated

Gene:
NFKBIA

Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18035, 25493, 282291, 406188, 4792, 480291

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516162

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Antigen:
IKK beta

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O14920, O88351

Gene Symbols:
Ikbkb

Immunogen:
Full-length human IKK beta recombinant protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
10A9B6

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16150, 3551

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516164

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Antigen:
TNFAIP3

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P21580, Q60769

Gene Symbols:
TNFAIP3

Immunogen:
Full length recombinant human A20.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
59A426

Conjugate:
Unconjugated

Gene:
TNFAIP3

Gene Alias:
A20; A20p37; A20p50; AISBL; OTU domain-containing protein 7C; OTUD7C; Putative DNA-binding protein A20; RP11-356I2.3; TNF alpha induced protein 3; TNF alpha-induced protein 3; TNFA1P2; TNFAIP3; TNFAIP3 (A20); Tnfip3; Tumor necrosis factor alpha-induced protein 3; tumor necrosis factor induced protein 3; tumor necrosis factor inducible protein A20; tumor necrosis factor, alpha induced protein 3; tumor necrosis factor, alpha-induced protein 3; zinc finger protein A20

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21929, 683206, 7128

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid