PIMA516183

p73 delta Monoclonal Antibody (38C674.2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516183-Each-of-1 In Stock ₹ 48,041.94

PIMA516183 - Each of 1

₹ 48,041.94

In Stock

Quantity

1

Base Price: ₹ 48,041.94

GST (18%): ₹ 8,647.549

Total Price: ₹ 56,689.489

Antigen

p73 delta

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

O15350, Q9JJP2

Gene Symbols

TP73, Trp73

Immunogen

Synthetic peptide (LYVGDPARHLAT) of p73 (deltaNp73) protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

38C674.2

Conjugate

Unconjugated

Gene

TP73

Gene Alias

deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; TP73; transformation related protein 73; Trp73; Tumor protein p73

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

22062, 362675, 7161

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Description p73 was identified as a long-lost cousin of tumor suppressor protein, p53 (4)
  • p73 has high homology with p53 as well as with p63, a gene implicated in the maintenance of epithelial stem cells
  • Significant homology between p53, p63, and p73 (approximately 63% amino acid identity in the DNA-binding domain suggest that they may have overlapping functions in the regulation of gene expression (3)
  • The targeted disruption of p73 gene leads to defects hippocampal dysgenesis, hydrocephalus, chronic inflammation and infections (2)
  • Recently, spilicing variant mRNAs of p73 has been identified in MCF-7, a breast carcinoma cell line
  • These mRNAs code for variant p73 proteins bearing distinct carboxy-terminal structures suggesting that the carboxy-terminal region of p73 may be important for the functions of this protein (1) It was found p73 to be upregulated in a significant fraction of anaplastic thyroid cancers, whereas it was not detectable in normal thyroid epithelial cells nor in papillary or follicular thyroid cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA516183

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Antigen:
p73 delta

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O15350, Q9JJP2

Gene Symbols:
TP73, Trp73

Immunogen:
Synthetic peptide (LYVGDPARHLAT) of p73 (deltaNp73) protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
38C674.2

Conjugate:
Unconjugated

Gene:
TP73

Gene Alias:
deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; TP73; transformation related protein 73; Trp73; Tumor protein p73

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22062, 362675, 7161

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516184

--


Antigen:
TLR3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O15455, Q99MB1

Gene Symbols:
TLR3

Immunogen:
A synthetic peptide corresponding to amino acids 55-85 of human TLR3 was used as immunogen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization, Western Blot

Clone:
40C1285.6

Conjugate:
Unconjugated

Gene:
TLR3

Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
142980, 482905, 7098

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516188

--


Antigen:
TLR3

Classification:
Monoclonal

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O15455, Q99MB1

Gene Symbols:
TLR3

Immunogen:
A synthetic peptide corresponding to amino acids 55-85 of human TLR3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
40C1285.6

Conjugate:
PE

Gene:
TLR3

Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
142980, 482905, 7098

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA516190

--


Antigen:
TLR8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P58682, Q9NR97

Gene Symbols:
TLR8

Immunogen:
KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850. It will cross-react with mouse TLR8.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rabbit

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
44C143

Conjugate:
Unconjugated

Gene:
TLR8

Gene Alias:
CD antigen 288; CD288; TLR8; toll like receptor 8; toll-like receptor 8; UNQ249/PRO286

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100328930, 170744, 51311

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid