PIMA516216

TLR4 Monoclonal Antibody (76B357.1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516216-Each-of-1 In Stock ₹ 48,640.86

PIMA516216 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

TLR4

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O00206, Q68Y56, Q9GL65, Q9QUK6, Q9QX05

Gene Symbols

TLR4

Immunogen

Synthetic peptide (aa 100-200 of human TLR4, isoform C, LPEYFSNLTNLEHL) of TLR4/CD284 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mammalia, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG2b κ

Applications

ChIP Assay, Dot Blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), In vitro Assay, Neutralization, Western Blot

Clone

76B357.1

Conjugate

Unconjugated

Gene

TLR4

Gene Alias

ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

21898, 281536, 29260, 399541, 7099

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Suggested positive control: intestine lysate (WB), ThP1, Ramos (flow)
  • TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
  • Mammalian cells respond to LPS by activating TLR4
  • TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
  • TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
  • Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
  • TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
  • Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
  • Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA516216

--


Antigen:
TLR4

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O00206, Q68Y56, Q9GL65, Q9QUK6, Q9QX05

Gene Symbols:
TLR4

Immunogen:
Synthetic peptide (aa 100-200 of human TLR4, isoform C, LPEYFSNLTNLEHL) of TLR4/CD284 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mammalia, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
ChIP Assay, Dot Blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), In vitro Assay, Neutralization, Western Blot

Clone:
76B357.1

Conjugate:
Unconjugated

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
21898, 281536, 29260, 399541, 7099

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA516221

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Antigen:
Phospho-Androgen Receptor (Ser213, Ser210)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P10275, P15207, P19091, Q9TT90

Gene Symbols:
AR

Immunogen:
Synthetic peptide corresponding to amino acids 207-221 (GRAREAS*GAPTSSKD) of human androgen receptor, containing the serine 213 phosphorylation.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
156C135.2

Conjugate:
Unconjugated

Gene:
AR

Gene Alias:
AIS; Andr; androgen nuclear receptor variant 2; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; androgen receptor splice variant 4b; Ar; AR8; AR-A; AW320017; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; RP11-383C12.1; SBMA; SMAX1; TFM; Variant AR45

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11835, 24208, 367, 403588

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA516222

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Antigen:
FOXP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q99JB6, Q9BZS1

Gene Symbols:
Foxp3

Immunogen:
Full-length His-tagged murine FOXP3 was used as the immunogen.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Western Blot

Clone:
3G3

Conjugate:
Unconjugated

Gene:
Foxp3

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20371, 50943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PIMA516224

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Antigen:
FOXP3

Classification:
Monoclonal

Concentration:
0.76 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q99JB6, Q9BZS1

Gene Symbols:
Foxp3

Immunogen:
Full-length His-tagged murine FOXP3 was used as the immunogen.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
3G3

Conjugate:
APC

Gene:
Foxp3

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20371, 50943

Content And Storage:
4° C, store in dark

Form:
Liquid