PIMA516237

TLR5 Monoclonal Antibody (19D759.2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516237-Each-of-1 In Stock ₹ 48,255.84

PIMA516237 - Each of 1

₹ 48,255.84

In Stock

Quantity

1

Base Price: ₹ 48,255.84

GST (18%): ₹ 8,686.051

Total Price: ₹ 56,941.891

Antigen

TLR5

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O60602, Q9JLF7

Gene Symbols

TLR5

Immunogen

KLH-conjugated synthetic peptide corresponding to a portion of human TLR5 between amino acids 700-800

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

19D759.2

Conjugate

Unconjugated

Gene

TLR5

Gene Alias

FLJ10052; MELIOS; MGC126430; MGC126431; RP11-239E10.1; SLE1; SLEB1; systemic lupus erythematosus susceptibility 1; TIL3; Tlr5; toll like receptor 5; Toll/interleukin-1 receptor-like protein 3; toll-like receptor 5

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

488605, 53791, 7100

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • TLR5 is a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents
  • TLR5 also plays a role in mediating detection of bacterial flagellins
  • TLR5 acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response
  • TLR5 protein binds to TIRAP and MyD88 via their respective TIR domains TLR5 is highly expressed in liver, and is detected in lung and at very low levels in most other tissues
  • The TLR5 gene lies in a locus that is associated with susceptibility to Salmonella
  • Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA)
  • The strain MOLF/Ei is highly susceptible to the infection, has a unique TLR5 haplotype and a lower expression of TRL5
  • A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires’ disease and demonstrates the importance of TLR5 in the innate immune response.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA516237

--


Antigen:
TLR5

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O60602, Q9JLF7

Gene Symbols:
TLR5

Immunogen:
KLH-conjugated synthetic peptide corresponding to a portion of human TLR5 between amino acids 700-800

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Dot Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
19D759.2

Conjugate:
Unconjugated

Gene:
TLR5

Gene Alias:
FLJ10052; MELIOS; MGC126430; MGC126431; RP11-239E10.1; SLE1; SLEB1; systemic lupus erythematosus susceptibility 1; TIL3; Tlr5; toll like receptor 5; Toll/interleukin-1 receptor-like protein 3; toll-like receptor 5

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
488605, 53791, 7100

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA516241

--


Antigen:
TLR5

Classification:
Monoclonal

Concentration:
0.71 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O60602, Q9JLF7

Gene Symbols:
TLR5

Immunogen:
KLH-conjugated synthetic peptide corresponding to a portion of human TLR5 between amino acids 700-800

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
19D759.2

Conjugate:
PE

Gene:
TLR5

Gene Alias:
FLJ10052; MELIOS; MGC126430; MGC126431; RP11-239E10.1; SLE1; SLEB1; systemic lupus erythematosus susceptibility 1; TIL3; Tlr5; toll like receptor 5; Toll/interleukin-1 receptor-like protein 3; toll-like receptor 5

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
488605, 53791, 7100

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA516247

--


Antigen:
TLR7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P58681, Q9NYK1

Gene Symbols:
TLR7

Immunogen:
Synthetic peptide (277 amino acid ( AA 562- 839)) of TLR7 protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
4G6

Conjugate:
Unconjugated

Gene:
TLR7

Gene Alias:
RGD1563357; RP23-139P21.3; Tlr7; TLR7-like; toll like receptor 7; toll-like receptor 7; toll-like receptor 7-like; UNQ248/PRO285

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
170743, 51284

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516250

--


Antigen:
Dectin 2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q6EIG7

Gene Symbols:
CLEC6A

Immunogen:
A blend of two peptides made to amino acids 44-63 and 90-106 of human Dectin-2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3D1

Conjugate:
Unconjugated

Gene:
CLEC6A

Gene Alias:
Clec4n; CLEC6A; Clec6a-ps1; CLECSF10; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10; C-type lectin domain family 4, member n; C-type lectin domain family 6 member A; C-type lectin domain family 6, member A; C-type lectin domain family 6, member A, pseudogene 1; C-type lectin superfamily member 10; DC-associated C-type lectin 2; dectin 2; DECTIN2; dectin-2; Dectin-2p; Dendritic cell-associated C-type lectin 2; natural killer complex lectin; Nkcl

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
93978

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid