PIMA516205
TLR4 Monoclonal Antibody (HTA125), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516205-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA516205 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
TLR4
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O00206, Q9QUK6
Gene Symbols
TLR4
Immunogen
Ba/F3 cell line expressing human TLR4 cell surface antigen
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, In vitro Assay, Neutralization, Western Blot
Clone
HTA125
Conjugate
Unconjugated
Gene
TLR4
Gene Alias
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
21898, 403417, 7099
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Suggested positive control: PBMCs or ThP1
- This antibody is not recommended for Western Blot applications
- TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
- This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
- Mammalian cells respond to LPS by activating TLR4
- TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
- TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
- Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
- TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
- Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
- Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
Compare Similar Items
Show Difference
Antigen: TLR4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O00206, Q9QUK6
Gene Symbols: TLR4
Immunogen: Ba/F3 cell line expressing human TLR4 cell surface antigen
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, In vitro Assay, Neutralization, Western Blot
Clone: HTA125
Conjugate: Unconjugated
Gene: TLR4
Gene Alias: ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 21898, 403417, 7099
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TLR4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O00206, Q9QUK6
Gene Symbols:
TLR4
Immunogen:
Ba/F3 cell line expressing human TLR4 cell surface antigen
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, In vitro Assay, Neutralization, Western Blot
Clone:
HTA125
Conjugate:
Unconjugated
Gene:
TLR4
Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
21898, 403417, 7099
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TLR4
Classification: Monoclonal
Concentration: 0.54 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O00206, Q9QUK6
Gene Symbols: TLR4
Immunogen: Ba/F3 cell line expressing human TLR4 cell surface antigen
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunocytochemistry
Clone: HTA125
Conjugate: PE
Gene: TLR4
Gene Alias: ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 21898, 403417, 7099
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
TLR4
Classification:
Monoclonal
Concentration:
0.54 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O00206, Q9QUK6
Gene Symbols:
TLR4
Immunogen:
Ba/F3 cell line expressing human TLR4 cell surface antigen
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
HTA125
Conjugate:
PE
Gene:
TLR4
Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
21898, 403417, 7099
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: TLR4/MD-2 Complex
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.: Q9JHF9, Q9QUK6
Gene Symbols: Ly96, Tlr4
Immunogen: Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone: MTS510
Conjugate: Unconjugated
Gene: Tlr4
Gene Alias: ARMD10; CD284; Esop1; ESOP-1; hToll; lipopolysaccharide response; Lps; Ly87; Ly96; Ly-96; Lymphocyte antigen 96; Md2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; Toll-like receptor 4
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17087, 21898
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TLR4/MD-2 Complex
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.:
Q9JHF9, Q9QUK6
Gene Symbols:
Ly96, Tlr4
Immunogen:
Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone:
MTS510
Conjugate:
Unconjugated
Gene:
Tlr4
Gene Alias:
ARMD10; CD284; Esop1; ESOP-1; hToll; lipopolysaccharide response; Lps; Ly87; Ly96; Ly-96; Lymphocyte antigen 96; Md2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; Toll-like receptor 4
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17087, 21898
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TLR4
Classification: Monoclonal
Concentration: 1.03 mg/mL
Formulation: 50mM sodium borate with 0.05% sodium azide
Gene Accession No.: O00206, Q9QUK6
Gene Symbols: TLR4
Immunogen: Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone: MTS510
Conjugate: FITC
Gene: TLR4
Gene Alias: ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 21898, 7099
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
TLR4
Classification:
Monoclonal
Concentration:
1.03 mg/mL
Formulation:
50mM sodium borate with 0.05% sodium azide
Gene Accession No.:
O00206, Q9QUK6
Gene Symbols:
TLR4
Immunogen:
Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
MTS510
Conjugate:
FITC
Gene:
TLR4
Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
21898, 7099
Content And Storage:
4° C, store in dark
Form:
Liquid