PIMA516213
TLR4 Monoclonal Antibody (MTS510), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516213-Each-of-1 | In Stock | ₹ 49,154.22 |
PIMA516213 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,154.22
GST (18%): ₹ 8,847.76
Total Price: ₹ 58,001.98
Antigen
TLR4
Classification
Monoclonal
Concentration
0.43 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q9QUK6
Gene Symbols
TLR4
Immunogen
Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
MTS510
Conjugate
PE
Gene
TLR4
Gene Alias
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
21898
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
- This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
- Mammalian cells respond to LPS by activating TLR4
- TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
- TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
- Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
- TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
- Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
- Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
Compare Similar Items
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Antigen: TLR4
Classification: Monoclonal
Concentration: 0.43 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q9QUK6
Gene Symbols: TLR4
Immunogen: Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: MTS510
Conjugate: PE
Gene: TLR4
Gene Alias: ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 21898
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
TLR4
Classification:
Monoclonal
Concentration:
0.43 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q9QUK6
Gene Symbols:
TLR4
Immunogen:
Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
MTS510
Conjugate:
PE
Gene:
TLR4
Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
21898
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: MiTF
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O75030, O88368, Q08874
Gene Symbols: MITF
Immunogen: A synthetic peptide mapping to the 300-350 amino acid region of MITF.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 21D1418
Conjugate: Unconjugated
Gene: MITF
Gene Alias: BCC2; Bhlhe32; black eyed white; bw; Class E basic helix-loop-helix protein 32; CMM8; Gsfbcc2; melanocyte inducing transcription factor; melanogenesis associated transcription factor; mi; microphtalmia-associated transcription factor; microphthalmia; microphthalmia associated transcription factor isoform M-; microphthalmia transcription factor; microphthalmia-associated transcription factor; microphthalmia-associated transcription factor A; microphthalmia-associated transcription factor isoform H; microphthalmia-associated transcription factor isoform H protein; microphthalmia-associated transcription factor Trnc-1; microphthalmia-associated transcription factor Trnc-2; microphthalmia-associated transcription factor variant 1; microphthalmia-associated transcription factor variant 2; microphthalmia-associated transcription factor variant 3; microphthalmia-associated transcription factor variant MITF-M(+); MITF; MITF-H; MITF-M; MITF-M-; transcription factor, isoform 7; vit; Vitiligo; Wh; WS2; WS2A
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17342, 25094, 4286
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MiTF
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O75030, O88368, Q08874
Gene Symbols:
MITF
Immunogen:
A synthetic peptide mapping to the 300-350 amino acid region of MITF.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
21D1418
Conjugate:
Unconjugated
Gene:
MITF
Gene Alias:
BCC2; Bhlhe32; black eyed white; bw; Class E basic helix-loop-helix protein 32; CMM8; Gsfbcc2; melanocyte inducing transcription factor; melanogenesis associated transcription factor; mi; microphtalmia-associated transcription factor; microphthalmia; microphthalmia associated transcription factor isoform M-; microphthalmia transcription factor; microphthalmia-associated transcription factor; microphthalmia-associated transcription factor A; microphthalmia-associated transcription factor isoform H; microphthalmia-associated transcription factor isoform H protein; microphthalmia-associated transcription factor Trnc-1; microphthalmia-associated transcription factor Trnc-2; microphthalmia-associated transcription factor variant 1; microphthalmia-associated transcription factor variant 2; microphthalmia-associated transcription factor variant 3; microphthalmia-associated transcription factor variant MITF-M(+); MITF; MITF-H; MITF-M; MITF-M-; transcription factor, isoform 7; vit; Vitiligo; Wh; WS2; WS2A
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17342, 25094, 4286
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Caspase 1
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P29452, P29466, P43527
Gene Symbols: CASP1
Immunogen: Two synthetic peptides from the human Caspase-1 protein (amino acids 371-390 and 31-45).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: 14F468
Conjugate: Unconjugated
Gene: CASP1
Gene Alias: CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 12362, 25166, 834
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Caspase 1
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P29452, P29466, P43527
Gene Symbols:
CASP1
Immunogen:
Two synthetic peptides from the human Caspase-1 protein (amino acids 371-390 and 31-45).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
14F468
Conjugate:
Unconjugated
Gene:
CASP1
Gene Alias:
CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
12362, 25166, 834
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TLR4
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O00206, Q68Y56, Q9GL65, Q9QUK6, Q9QX05
Gene Symbols: TLR4
Immunogen: Synthetic peptide (aa 100-200 of human TLR4, isoform C, LPEYFSNLTNLEHL) of TLR4/CD284 protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Mammalia, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG2b κ
Applications: ChIP Assay, Dot Blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), In vitro Assay, Neutralization, Western Blot
Clone: 76B357.1
Conjugate: Unconjugated
Gene: TLR4
Gene Alias: ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 21898, 281536, 29260, 399541, 7099
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TLR4
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O00206, Q68Y56, Q9GL65, Q9QUK6, Q9QX05
Gene Symbols:
TLR4
Immunogen:
Synthetic peptide (aa 100-200 of human TLR4, isoform C, LPEYFSNLTNLEHL) of TLR4/CD284 protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mammalia, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
ChIP Assay, Dot Blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), In vitro Assay, Neutralization, Western Blot
Clone:
76B357.1
Conjugate:
Unconjugated
Gene:
TLR4
Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
21898, 281536, 29260, 399541, 7099
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid