PIMA516250

Dectin 2 Monoclonal Antibody (3D1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516250-Each-of-1 In Stock ₹ 45,218.46

PIMA516250 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

Dectin 2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q6EIG7

Gene Symbols

CLEC6A

Immunogen

A blend of two peptides made to amino acids 44-63 and 90-106 of human Dectin-2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG3 κ

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

3D1

Conjugate

Unconjugated

Gene

CLEC6A

Gene Alias

Clec4n; CLEC6A; Clec6a-ps1; CLECSF10; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10; C-type lectin domain family 4, member n; C-type lectin domain family 6 member A; C-type lectin domain family 6, member A; C-type lectin domain family 6, member A, pseudogene 1; C-type lectin superfamily member 10; DC-associated C-type lectin 2; dectin 2; DECTIN2; dectin-2; Dectin-2p; Dendritic cell-associated C-type lectin 2; natural killer complex lectin; Nkcl

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

93978

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Dectin-2 is a C-type lectin expressed by dendritic cells, macrophages and inflammatory monocytes
  • It is a type II membrane receptor, with a short cytoplasmic tail, and a C-terminal C-type lectin domain
  • Dectin-2 is a receptor with specificity for high mannose structures and mediates cytokine production from DC and other antigen presenting cells
  • Though, Dectin-2 has no obvious signaling motifs attached to CP tail, reports indicate that Dectin-2 employs FcRg for internalization and to activate NF-kappaB pathway for cytokine production
  • Though it shares only 20-25% of homology with Dectin-1, it functions similarly as pattern recognition receptor (PRR) for fungal infections, to activate both innate (Syk-CARD9 innate signaling pathway) and adaptive immune responses (by activation of DC) to fungal infections
  • Thus Dectin-2 is a connector molecule of both innate and adaptive immunity functioning at DC level.

Compare Similar Items

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Img

Thermo Scientific

PIMA516250

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Antigen:
Dectin 2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q6EIG7

Gene Symbols:
CLEC6A

Immunogen:
A blend of two peptides made to amino acids 44-63 and 90-106 of human Dectin-2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3D1

Conjugate:
Unconjugated

Gene:
CLEC6A

Gene Alias:
Clec4n; CLEC6A; Clec6a-ps1; CLECSF10; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10; C-type lectin domain family 4, member n; C-type lectin domain family 6 member A; C-type lectin domain family 6, member A; C-type lectin domain family 6, member A, pseudogene 1; C-type lectin superfamily member 10; DC-associated C-type lectin 2; dectin 2; DECTIN2; dectin-2; Dectin-2p; Dendritic cell-associated C-type lectin 2; natural killer complex lectin; Nkcl

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
93978

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516252

--


Antigen:
MIP-3 alpha

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P78556

Gene Symbols:
CCL20

Immunogen:
full length protein MIP-3a

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
4N5F7

Conjugate:
Unconjugated

Gene:
CCL20

Gene Alias:
beta chemokine exodus-1; beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; LARC; Liver and activation-regulated chemokine; macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 a; MIP 3alpha; MIP 3a; MIP3 a; MIP3 alpha; MIP3 a; MIP-3[a]; MIP3A; MIP-3A; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; small-inducible cytokine A20; St38

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6364

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516253

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Antigen:
MIP-3 alpha

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.:
O89093

Gene Symbols:
CCL20

Immunogen:
full length protein MIP-3 alpha

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
4N8C7

Conjugate:
Unconjugated

Gene:
CCL20

Gene Alias:
beta chemokine exodus-1; beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; C-C motif chemokine 20; C-C motif chemokine ligand 20; Ccl20; CCL20(1-64); CCL20(1-67); CCL20(2-70); chemokine (C-C motif) ligand 20; CKb4; Exodus; exodus-1; LARC; Liver and activation-regulated chemokine; macrophage inflammatory protein 3 alpha; MIP 3 a; MIP 3 a; MIP 3alpha; MIP 3a; MIP3 a; MIP3 alpha; MIP3 a; MIP-3[a]; MIP3A; MIP-3A; MIP-3-alpha; M-MIP-3-alpha; SCYA20; small inducible cytokine subfamily A (Cys-Cys), member 20; small inducible cytokine subfamily A20; small-inducible cytokine A20; St38

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20297

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516255

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Antigen:
EBI3

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O35228

Gene Symbols:
EBI3

Immunogen:
full length recombinant mouse EBI3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Western Blot

Clone:
10J706

Conjugate:
Unconjugated

Gene:
EBI3

Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; IL-27; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; IL35 subunit; interleukin-27 subunit beta

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
50498

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid