PIMA516365

FOXP3 Monoclonal Antibody (SP97), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516365-Each-of-1 In Stock ₹ 59,549.76

PIMA516365 - Each of 1

₹ 59,549.76

In Stock

Quantity

1

Base Price: ₹ 59,549.76

GST (18%): ₹ 10,718.957

Total Price: ₹ 70,268.717

Antigen

FOXP3

Classification

Monoclonal

Concentration

0.049 mg/mL

Formulation

PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.

Q9BZS1

Gene Symbols

Foxp3

Immunogen

Synthetic peptide corresponding to C-terminus of human FOXP3 protein.

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin)

Clone

SP97

Conjugate

Unconjugated

Gene

Foxp3

Gene Alias

AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

50943

Content And Storage

-20°, C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using an EDTA buffer, pH 8.0, for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
  • A suggested positive control is tonsil tissue
  • FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis
  • FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells
  • FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells
  • Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice
  • In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome
  • Transcript variants of FOXP3 encoding different isoforms have been identified
  • In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.

Compare Similar Items

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Img

Thermo Scientific

PIMA516365

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Antigen:
FOXP3

Classification:
Monoclonal

Concentration:
0.049 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
Q9BZS1

Gene Symbols:
Foxp3

Immunogen:
Synthetic peptide corresponding to C-terminus of human FOXP3 protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP97

Conjugate:
Unconjugated

Gene:
Foxp3

Gene Alias:
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
50943

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA516368

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Antigen:
Glypican 3

Classification:
Monoclonal

Concentration:
0.466 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P51654

Gene Symbols:
GPC3

Immunogen:
Synthetic peptide derived from C-terminus of human glypican-3 protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP86

Conjugate:
Unconjugated

Gene:
GPC3

Gene Alias:
defective in Simpson-Golabi-Behmel overgrowth syndrome; DGSX; glypican 3; glypican proteoglycan 3; glypican-3; Glypican-3 alpha subunit; Glypican-3 beta subunit; Gpc3; GTR22; GTR2-2; heparan sulphate proteoglycan; intestinal protein OCI-5; MXR7; OCI5; OCI-5; proteoglycan GPC3; SDYS; secreted glypican-3; SGB; SGBS; SGBS1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2719

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA516372

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Antigen:
Cytokeratin 5

Classification:
Monoclonal

Concentration:
Conc. not determined

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
P13647, Q6P6Q2, Q922U2

Gene Symbols:
KRT5

Immunogen:
Synthetic peptide from C-terminus of human cytokeratin 5.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
SP27

Conjugate:
Unconjugated

Gene:
KRT5

Gene Alias:
3300001P10Rik; 58 kDa cytokeratin; alpha keratin; AW146334; CK5; CK-5; ckii; ckii protein; cytokeratin 5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin complex 2, basic, gene 5; keratin type II, tail domain; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 5; keratin 5; keratin-5; Krt2-5; KRT5; KRT5A; Sak57; Tfip8; tuftelin interacting protein 8; type II alpha-keratin IIA; type II cytokeratin; type-II keratin Kb5; wu:fb02h09; wu:fj02d02; wu:fk78b12; zfCKII

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
110308, 369017, 3852

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516373

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Antigen:
Cytokeratin 6

Classification:
Monoclonal

Concentration:
Not Determined

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
P02538, P04259, P48668, P50446, Q4FZU2, Q9Z331

Gene Symbols:
KRT6A, KRT6B, KRT6C

Immunogen:
Synthetic peptide derived from C-terminus of human keratin 6 protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
SP87

Conjugate:
Unconjugated

Gene:
KRT6C

Gene Alias:
2310016L08Rik; 60-kDa keratin; BB144589; CK6A; CK-6A; CK6B; CK-6B; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6B; cytokeratin 6C; cytokeratin 6D; cytokeratin-6A; Cytokeratin-6B; cytokeratin-6C; Cytokeratin-6D; Cytokeratin-6E; Hom s 5; K6A; K6a keratin; K6B; K6C; K6D; K6E; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin 6B; keratin 6B, type II; keratin 6C; keratin 6C, type II; keratin 6E; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6b; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, epidermal, type II, K6B; keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 6B; keratin, type II cytoskeletal 6C; keratin-6A; Keratin-6-alpha; Keratin-6B; keratin-6-beta; keratin-6C; keratin-like 1 (a type II keratin sequence); Krt2-6; Krt2-6a; Krt2-6b; Krt2-6c; Krt6; Krt6a; Krt6b; KRT6C; KRT6D; KRT6E; KRTL1; LOC683313; mK6[a]; mK6[b]; MK6a; mK6-alpha; mK6-beta; PC2; PC3; PC4; PPKNEFD; similar to keratin complex 2, basic, gene 6a; type-II keratin Kb10; Type-II keratin Kb12; type-II keratin Kb6

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
120093743, 16687, 16688, 286887, 3853, 3854, 683313

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid