PIMA516394

Progesterone Receptor Monoclonal Antibody (SP42), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516394-Each-of-1 In Stock ₹ 78,116.28

PIMA516394 - Each of 1

₹ 78,116.28

In Stock

Quantity

1

Base Price: ₹ 78,116.28

GST (18%): ₹ 14,060.93

Total Price: ₹ 92,177.21

Antigen

Progesterone Receptor

Classification

Monoclonal

Conjugate

Unconjugated

Gene

PGR

Gene Alias

9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

5241

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

SP42

Formulation

PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.

P06401

Gene Symbols

PGR

Immunogen

Recombinant protein encoding human progesterone receptor 412-526 aa

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
  • A suggested positive control is breast carcinoma
  • The progesterone receptor (PR) is a member of the steroid family of nuclear receptors
  • The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy
  • PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites
  • PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation
  • PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus
  • This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity
  • In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins
  • Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription
  • A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Compare Similar Items

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Img

Thermo Scientific

PIMA516394

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Antigen:
Progesterone Receptor

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP42

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA516395

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Antigen:
PSMA

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
FOLH1

Gene Alias:
Cell growth-inhibiting gene 27 protein; FGCP; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1; FOLH; Folh1; Folylpoly-gamma-glutamate carboxypeptidase; GCP2; GCPII; GIG27; glutamate carboxylase II; glutamate carboxypeptidase 2; Glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; mopsm; Naalad; NAALAD1; NAALAdase; NAALADase I; N-acetylated alpha-linked acidic dipeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; prostate specific membrane antigen; prostate specific membrane antigen variant F; prostate-specific membrane antigen; Prostate-specific membrane antigen homolog; PSM; PSMA; pteroylpoly-gamma-glutamate carboxypeptidase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2346

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP29

Formulation:
PBS, TBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
Q04609

Gene Symbols:
FOLH1

Immunogen:
Synthetic peptide derived from C-terminus of human PSMA.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA516402

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Antigen:
Synaptophysin

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Syp

Gene Alias:
A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
20977, 24804, 6855

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
SP11

Formulation:
tissue culture supernatant diluted in TBS with 1% BSA and 0.1% sodium azide; pH 7.5

Gene Accession No.:
P07825, P08247, Q62277

Gene Symbols:
Syp

Immunogen:
Synthetic peptide corresponding to C-terminus of human synaptophysin.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA516405

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Antigen:
Thymidylate Synthase

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TYMS

Gene Alias:
HST422; MGC88736; OK/SW-cl.29; Thymidylate synthase; thymidylate synthetase; TMS; TS; Tsase; Tyms; tysy

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7298

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
SP112

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P04818

Gene Symbols:
TYMS

Immunogen:
Synthetic peptide near C-terminus of human TS.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG