PIMA516477

Dectin 1 (soluble) Monoclonal Antibody (2A11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516477-Each-of-1 In Stock ₹ 52,704.96

PIMA516477 - Each of 1

₹ 52,704.96

In Stock

Quantity

1

Base Price: ₹ 52,704.96

GST (18%): ₹ 9,486.893

Total Price: ₹ 62,191.853

Antigen

Dectin 1 (soluble)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q6QLQ4

Gene Symbols

Clec7a

Immunogen

Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

2A11

Conjugate

Unconjugated

Gene

Clec7a

Gene Alias

Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

56644

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • The epitope recognized by 2A11 is sensitive to H2O2 treatment, therefore quenching with 0.3% H2O2 should be performed after incubation with the primary antibody
  • The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing
  • We recommend the use of acetone fixation for frozen sections
  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1
  • CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells
  • It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM)
  • CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response
  • Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA516477

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
2A11

Conjugate:
Unconjugated

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA516478

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
2A11

Conjugate:
Unconjugated

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA516479

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
2A11

Conjugate:
FITC

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA516480

--


Antigen:
Dectin 1 (soluble)

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6QLQ4

Gene Symbols:
Clec7a

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
2A11

Conjugate:
FITC

Gene:
Clec7a

Gene Alias:
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56644

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid