PIMA516949
TGF beta-1 Monoclonal Antibody (TB21), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516949-Each-of-1 | In Stock | ₹ 53,047.20 |
PIMA516949 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,047.20
GST (18%): ₹ 9,548.496
Total Price: ₹ 62,595.696
Antigen
TGF beta-1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P01137, P04202, P17246, P50414
Gene Symbols
Tgfb1
Immunogen
Human Transforming Growth Factor Beta 1 from platelets
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
TB21
Conjugate
Unconjugated
Gene
Tgfb1
Gene Alias
CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF β; TGF β 1; TGF β1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFβ1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor β1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100008645, 21803, 443417, 59086, 7040
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- TB21 has been used successfully on FFPE tissues without pretreatment
- A suggested positive control for immunohistochemical applications is human breast carcinoma
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- The recommended shelf-life for this product is 6 months
- Mouse anti Human TGF beta antibody, clone TB21 recognizes both human platelet-derived and recombinant TGF-beta1 in enzyme-linked immunosorbent assay (ELISA)
- TGF beta-1 (TGFB1, Transforming Growth Factor Beta 1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues
- Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its pro-domain
- Activation of TGF beta-1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins
- Latent forms are complexes of TGF beta-1, an amino-terminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP
- TGF beta-1 helps regulates proliferation, differentiation, adhesion, migration in many cell types
- Many cells have TGF beta receptors, and the protein positively and negatively regulates many other growth factors
- TGF beta-1 is cleaved into a latency-associated peptide and a mature TGF beta-1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGF beta-1 homodimer
- The mature peptide may also form heterodimers with other TGF beta family members
- The gene for TGF beta-1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease and cystic fibrosis.
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Antigen: TGF beta-1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with <0.1% sodium azide
Gene Accession No.: P01137, P04202, P17246, P50414
Gene Symbols: Tgfb1
Immunogen: Human Transforming Growth Factor Beta 1 from platelets
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: TB21
Conjugate: Unconjugated
Gene: Tgfb1
Gene Alias: CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF β; TGF β 1; TGF β1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFβ1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor β1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100008645, 21803, 443417, 59086, 7040
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TGF beta-1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with <0.1% sodium azide
Gene Accession No.:
P01137, P04202, P17246, P50414
Gene Symbols:
Tgfb1
Immunogen:
Human Transforming Growth Factor Beta 1 from platelets
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mink, Mouse, Mustelid, Ovine, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
TB21
Conjugate:
Unconjugated
Gene:
Tgfb1
Gene Alias:
CED; cytokine; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGF b; TGF b 1; TGF beta; tgf beta 1; tgf beta1; TGF beta-1; TGF beta-1 protein; TGF β; TGF β 1; TGF β1; Tgfb; TGFB1; TGF-B1; Tgfb-1; TGFbeta; TGF-beta 1; TGF-beta 1 protein; TGFbeta1; TGF-beta1; TGF-beta-1; TGFβ1; Transforming growth factor; transforming growth factor b1; transforming growth factor beta; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor beta-1 proprotein; transforming growth factor beta-1; transforming growth factor β1; transforming growth factor, beta 1; transforming growth factor, beta 1 (Camurati-Engelmann disease); transforming growth factor, beta-1; transforming growth factor-beta 1; transforming growth factor-beta I; transforming growth factor-beta-1; transforming growth factor-beta-1 precursor; unnamed protein product
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100008645, 21803, 443417, 59086, 7040
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD31
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.: Q3SWT0
Gene Symbols: Pecam1
Immunogen: Activated, Lewis rat derived microglial cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry
Clone: TLD-3A12
Conjugate: Biotin
Gene: Pecam1
Gene Alias: C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 29583, 718302
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD31
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.:
Q3SWT0
Gene Symbols:
Pecam1
Immunogen:
Activated, Lewis rat derived microglial cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
TLD-3A12
Conjugate:
Biotin
Gene:
Pecam1
Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
29583, 718302
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD3/HLA Class 2
Classification: Cocktail
Concentration: Conc. Not Determined
Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.: P01911, P01920, P04234, P04440, P07766, P09693
Gene Symbols: CD3D, CD3E, CD3G, HLA-DPB1, HLA-DQB1, HLA-DRB1
Immunogen: Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome, Human B-CLL cells
Quantity: 50 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1, IgG2a
Applications: Flow Cytometry
Clone: UCHT1/WR18
Conjugate: PE
Gene: CD3G
Gene Alias: beta1 domain MHC class II HLA DPB; CD3 antigen, delta subunit; CD3 delta; CD3 epsilon; CD3D; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; CD3E; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3-epsilon; CD3G; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; CD74 antigen; CELIAC1; class II HLA beta chain; Clone P2-beta-3; DHLAG; DPB1; DR-16; DRB1; DRw10; DW2.2/DR2.2; FLJ18683; HLA class II antigen; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; HLA DP14-beta chain; HLADG; HLA-DP; HLA-DP histocompatibility type, beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DQ; HLA-DQB; HLA-DQB1; HLA-DR1B; HLA-DRB; HLA-DRB1; HLA-DRB2; HLA-DR-gamma; human leucocyte antigen DRB1; IA-gamma; IDDM1; IMD17; IMD18; IMD19; lymphocyte antigen; lymphocyte antigen DRB1; major histocompatibility complex class II antigen beta chain; major histocompatibility complex, class II, DP beta 1; major histocompatibility complex, class II, DQ beta 1; major histocompatibility complex, class II, DR beta 1; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II antigen DQB1; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DP-beta-1; MHC class II HLA-DQ beta glycoprotein; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DRB1; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MHC class2 antigen; MHC DQ beta; MHC HLA DPB1; OKT3, delta chain; SS1; T3D; T3E; T3G; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; TCRE
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3115, 3119, 3123, 915, 916, 917
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Lyophilized
Antigen:
CD3/HLA Class 2
Classification:
Cocktail
Concentration:
Conc. Not Determined
Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.:
P01911, P01920, P04234, P04440, P07766, P09693
Gene Symbols:
CD3D, CD3E, CD3G, HLA-DPB1, HLA-DQB1, HLA-DRB1
Immunogen:
Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome, Human B-CLL cells
Quantity:
50 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1, IgG2a
Applications:
Flow Cytometry
Clone:
UCHT1/WR18
Conjugate:
PE
Gene:
CD3G
Gene Alias:
beta1 domain MHC class II HLA DPB; CD3 antigen, delta subunit; CD3 delta; CD3 epsilon; CD3D; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; CD3E; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3-epsilon; CD3G; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; CD74 antigen; CELIAC1; class II HLA beta chain; Clone P2-beta-3; DHLAG; DPB1; DR-16; DRB1; DRw10; DW2.2/DR2.2; FLJ18683; HLA class II antigen; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; HLA DP14-beta chain; HLADG; HLA-DP; HLA-DP histocompatibility type, beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DQ; HLA-DQB; HLA-DQB1; HLA-DR1B; HLA-DRB; HLA-DRB1; HLA-DRB2; HLA-DR-gamma; human leucocyte antigen DRB1; IA-gamma; IDDM1; IMD17; IMD18; IMD19; lymphocyte antigen; lymphocyte antigen DRB1; major histocompatibility complex class II antigen beta chain; major histocompatibility complex, class II, DP beta 1; major histocompatibility complex, class II, DQ beta 1; major histocompatibility complex, class II, DR beta 1; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II antigen DQB1; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DP-beta-1; MHC class II HLA-DQ beta glycoprotein; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DRB1; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MHC class2 antigen; MHC DQ beta; MHC HLA DPB1; OKT3, delta chain; SS1; T3D; T3E; T3G; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain; TCRE
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3115, 3119, 3123, 915, 916, 917
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Lyophilized
Antigen: CD44v10
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P16070
Gene Symbols: CD44
Immunogen: proprietary
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Western Blot
Clone: VFF-14
Conjugate: Unconjugated
Gene: CD44
Gene Alias: AL133330.1; AU023126; AW121933; AW146109; Cd44; CD44 antigen; CD44 molecule (Indian blood group); CD44 splice variant; CD44 var; CD44 variant; CD44A; CD44v10; CDw44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; H-CAM v10; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCHI; HUTCH-I; Hyaluronate receptor; IN; LHR; Ly-24; Lymphocyte antigen 24; MC56; MDU2; MDU3; METAA; MGC10468; MIC4; MUTCH-I; PGP I; Pgp1; PGP-1; PGP-I; phagocytic glycoprotein 1; Phagocytic glycoprotein I; RHAMM; soluble CD44
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 960
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CD44v10
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P16070
Gene Symbols:
CD44
Immunogen:
proprietary
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Western Blot
Clone:
VFF-14
Conjugate:
Unconjugated
Gene:
CD44
Gene Alias:
AL133330.1; AU023126; AW121933; AW146109; Cd44; CD44 antigen; CD44 molecule (Indian blood group); CD44 splice variant; CD44 var; CD44 variant; CD44A; CD44v10; CDw44; cell surface glycoprotein CD44; Cell surface glycoprotein CD44 (hyaluronate binding protein); chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; H-CAM v10; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCHI; HUTCH-I; Hyaluronate receptor; IN; LHR; Ly-24; Lymphocyte antigen 24; MC56; MDU2; MDU3; METAA; MGC10468; MIC4; MUTCH-I; PGP I; Pgp1; PGP-1; PGP-I; phagocytic glycoprotein 1; Phagocytic glycoprotein I; RHAMM; soluble CD44
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
960
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid