PIMA517770

I-Ap Monoclonal Antibody (7-16.17), PE, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517770-Each-of-1 In Stock ₹ 21,261.66

PIMA517770 - Each of 1

₹ 21,261.66

In Stock

Quantity

1

Base Price: ₹ 21,261.66

GST (18%): ₹ 3,827.099

Total Price: ₹ 25,088.759

Antigen

I-Ap

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.

P04230

Gene Symbols

H2-Eb1

Immunogen

B10.p

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

7-16.17

Conjugate

PE

Gene

H2-Eb1

Gene Alias

cell surface glycoprotein; H-2 class II histocompatibility antigen, I-E beta chain; H2Eb; H-2Eb; H2-Eb1; histocompatibility 2, class II antigen E beta; Ia4; Ia-4; I-E beta MHC class II; major histocompatibility complex H-2E beta chain; MHC class II IE-b; MHC H2-IE-beta cell surface glycoprotein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

14969

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • MA5-17770 targets I-Ap in FACS applications and shows reactivity with Mouse samples
  • The MA5-17770 immunogen is b10.p
  • MHC Class II (I-Ap) is a protein complex found on the surface of cells in vertebrates
  • Its main function is to present peptides derived from extracellular proteins to T cells for immune recognition
  • MHC Class II (I-Ap) is composed of an alpha and beta chain, both of which contribute to the peptide-binding groove
  • MHC Class II (I-Ap) is primarily restricted to antigen-presenting cells, including dendritic cells, macrophages, and B cells
  • These cells are responsible for capturing and processing antigens from the extracellular environment
  • Once the antigens are internalized, they are broken down into smaller peptides, which then bind to MHC Class II molecules within the endosomal compartments of these cells
  • MHC Class II (I-Ap) consists of an extracellular domain, a transmembrane domain, and a cytoplasmic tail
  • The extracellular domain is responsible for interacting with the antigenic peptides, while the transmembrane domain anchors the MHC Class II molecule to the cell membrane
  • The cytoplasmic tail plays a role in intracellular signaling events
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA517770

--


Antigen:
I-Ap

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P04230

Gene Symbols:
H2-Eb1

Immunogen:
B10.p

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
7-16.17

Conjugate:
PE

Gene:
H2-Eb1

Gene Alias:
cell surface glycoprotein; H-2 class II histocompatibility antigen, I-E beta chain; H2Eb; H-2Eb; H2-Eb1; histocompatibility 2, class II antigen E beta; Ia4; Ia-4; I-E beta MHC class II; major histocompatibility complex H-2E beta chain; MHC class II IE-b; MHC H2-IE-beta cell surface glycoprotein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14969

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA517772

--


Antigen:
I-Ak

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P01910, P04227, P04228, P14434, P14435, P14436, P14437, P14438, P23150

Gene Symbols:
H2-Aa

Immunogen:
A.TL spleen

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
14V.18

Conjugate:
Biotin

Gene:
H2-Aa

Gene Alias:
A alpha; Aalpha; H-2 class II histocompatibility antigen, A-B alpha chain; H-2 class II histocompatibility antigen, A-F alpha chain; H-2 class II histocompatibility antigen, A-K alpha chain; H-2 class II histocompatibility antigen, A-Q alpha chain; H-2 class II histocompatibility antigen, A-R alpha chain; H-2 class II histocompatibility antigen, A-S alpha chain; H-2 class II histocompatibility antigen, A-U alpha chain; H2Aa; H-2Aa; H2-Aa; histocompatibility 2, class II antigen A, alpha; Ia1; Ia-1; IAalpha; I-Aalpha; major histocompatibility protein class II alpha chain; MHC class II antigen A alpha isoform-004; MHC-II I-A(d) alpha

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14960

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA517773

--


Antigen:
I-Ak

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P01910, P04227, P04228, P14434, P14435, P14436, P14437, P14438, P23150

Gene Symbols:
H2-Aa

Immunogen:
A.TL spleen

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
14V.18

Conjugate:
FITC

Gene:
H2-Aa

Gene Alias:
A alpha; Aalpha; H-2 class II histocompatibility antigen, A-B alpha chain; H-2 class II histocompatibility antigen, A-F alpha chain; H-2 class II histocompatibility antigen, A-K alpha chain; H-2 class II histocompatibility antigen, A-Q alpha chain; H-2 class II histocompatibility antigen, A-R alpha chain; H-2 class II histocompatibility antigen, A-S alpha chain; H-2 class II histocompatibility antigen, A-U alpha chain; H2Aa; H-2Aa; H2-Aa; histocompatibility 2, class II antigen A, alpha; Ia1; Ia-1; IAalpha; I-Aalpha; major histocompatibility protein class II alpha chain; MHC class II antigen A alpha isoform-004; MHC-II I-A(d) alpha

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14960

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA517774

--


Antigen:
I-Ak

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
P01910, P04227, P04228, P14434, P14435, P14436, P14437, P14438, P23150

Gene Symbols:
H2-Aa

Immunogen:
A.TL spleen

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
14V.18

Conjugate:
PE

Gene:
H2-Aa

Gene Alias:
A alpha; Aalpha; H-2 class II histocompatibility antigen, A-B alpha chain; H-2 class II histocompatibility antigen, A-F alpha chain; H-2 class II histocompatibility antigen, A-K alpha chain; H-2 class II histocompatibility antigen, A-Q alpha chain; H-2 class II histocompatibility antigen, A-R alpha chain; H-2 class II histocompatibility antigen, A-S alpha chain; H-2 class II histocompatibility antigen, A-U alpha chain; H2Aa; H-2Aa; H2-Aa; histocompatibility 2, class II antigen A, alpha; Ia1; Ia-1; IAalpha; I-Aalpha; major histocompatibility protein class II alpha chain; MHC class II antigen A alpha isoform-004; MHC-II I-A(d) alpha

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14960

Content And Storage:
4° C, do not freeze

Form:
Liquid