PIMA518072

Methyl-PP2A alpha (Leu309) Monoclonal Antibody (2A10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA518072-Each-of-1 In Stock ₹ 57,581.88

PIMA518072 - Each of 1

₹ 57,581.88

In Stock

Quantity

1

Base Price: ₹ 57,581.88

GST (18%): ₹ 10,364.738

Total Price: ₹ 67,946.618

Antigen

Methyl-PP2A alpha (Leu309)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P63330, P63331, P67775

Gene Symbols

PPP2CA

Immunogen

A KLH-coupled peptide with the sequence: KLH-C-βA-RRTPDYFL-OMe

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunoprecipitation, Western Blot

Clone

2A10

Conjugate

Unconjugated

Gene

PPP2CA

Gene Alias

B55-GAMMA; hypothetical protein; IMYPNO; IMYPNO1; Methyl-PPP2CA; MGC33570; PP2A; PP2A alpha; PP2A C terminal; PP2A L9; PP2A Leucine 9; Pp2a1; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; Ppp2ca; PR52; PR55G; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2 catalytic subunit alpha; protein phosphatase 2, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; protein phosphatase 2,catalytic subunit alpha isozyme; protein phosphatase 2A alpha subunit; protein phosphatase 2A catalytic subunit alpha isoform; protein phosphatase 2a, catalytic subunit, alpha isoform; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A; protein phosphatase-2A-alpha; R75353; replication protein C; RP-C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; unnamed protein product

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

19052, 24672, 5515

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody recognizes the C-terminal methylated form of PP2A (C subunit)
  • The c-terminal sequence, as well as the carboxy-methylation, is 100% conserved in human, mouse and yeast
  • Western blot results show a band at 36 kDa, which matches the predicted molecular weight
  • The c-terminal sequence (as well as the carboxy-methylation) is absolutely conserved from human, mouse to yeast
  • In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis
  • A group of proteins that are intimately involved in this process are the protein phosphatases
  • In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit
  • Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C
  • The PP2A family comprises subfamily members PP2A alpha and PP2A beta
  • An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.

Compare Similar Items

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Img

Thermo Scientific

PIMA518072

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Antigen:
Methyl-PP2A alpha (Leu309)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P63330, P63331, P67775

Gene Symbols:
PPP2CA

Immunogen:
A KLH-coupled peptide with the sequence: KLH-C-βA-RRTPDYFL-OMe

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunoprecipitation, Western Blot

Clone:
2A10

Conjugate:
Unconjugated

Gene:
PPP2CA

Gene Alias:
B55-GAMMA; hypothetical protein; IMYPNO; IMYPNO1; Methyl-PPP2CA; MGC33570; PP2A; PP2A alpha; PP2A C terminal; PP2A L9; PP2A Leucine 9; Pp2a1; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; Ppp2ca; PR52; PR55G; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2 catalytic subunit alpha; protein phosphatase 2, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; protein phosphatase 2,catalytic subunit alpha isozyme; protein phosphatase 2A alpha subunit; protein phosphatase 2A catalytic subunit alpha isoform; protein phosphatase 2a, catalytic subunit, alpha isoform; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A; protein phosphatase-2A-alpha; R75353; replication protein C; RP-C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
19052, 24672, 5515

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA518073

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Antigen:
Progerin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P02545

Gene Symbols:
LMNA

Immunogen:
Synthetic peptide conjugated to KLH derived from within residues 604-611 (GAQSPQNC) at the C terminus of Human Progerin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
13A4D4

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C; lamin A/C-like 1; Lamin AC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4000

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA518074

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Antigen:
H4K20me3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
P62805, Q27894

Gene Symbols:
H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9, his-4

Immunogen:
Synthetic peptide of Human Histone H4 (Immunogen sequence: 15-AKRHR(Kme3)VLRDN-25 (branched))

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
C. elegans, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Dot Blot, ELISA, Western Blot

Clone:
6F8-D9

Conjugate:
Unconjugated

Gene:
H4C1

Gene Alias:
CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/j; H4/K; H4/M; H4/n; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4c11; H4C12; H4C13; H4c14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4Lys20me3; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; Hist1h4h; Hist1h4i; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; HIST2H4A; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H4; Histone H4A; Histone H4K20me3; histone IV, family 2; K06C4.12; K06C4.4; methyl Histone 3; methyl Histone H3; T10C6.11; Trimethyl H4; Tri-methyl H4; Trimethyl Histone H4; Tri-methyl Histone H4; Tri-Methyl-H4 K20; Tri-Methyl-H4 Lys20; Tri-Methyl-Histone H4 K20; Tri-Methyl-Histone H4 Lys20; X04652

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
121504, 180072, 8294, 8359, 8363, 8366, 8367, 8370

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA518075

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Antigen:
Nesprin 2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1% sodium azide

Gene Accession No.:
Q8WXH0

Gene Symbols:
SYNE2

Immunogen:
Residues 1-459 of human Nesprin-2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunocytochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot

Clone:
K20-478-5

Conjugate:
Unconjugated

Gene:
SYNE2

Gene Alias:
6820443O06Rik; AW546258; D12Ertd777e; EDMD5; KASH domain-containing protein 2; KASH2; KIAA1011; MGC96690; mKIAA1011; Nesp2; Nesp2g; nesprin 2; nesprin-2; NUA; NUANCE; nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing nuclear envelope protein 2; spectrin repeat containing, nuclear envelope 2; synaptic nuclear envelope 2; synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; SYNE2; Syne-2; TROPH

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
23224

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid