PIMA524779
SCN5A Monoclonal Antibody (4G8:1G7), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524779-Each-of-1 | In Stock | ₹ 45,132.90 |
PIMA524779 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,132.90
GST (18%): ₹ 8,123.922
Total Price: ₹ 53,256.822
Antigen
SCN5A
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q14524
Gene Symbols
SCN5A
Immunogen
Peptide (14mer) from an extracellular domain of Nav1.5
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgM
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Clone
4G8:1G7
Conjugate
Unconjugated
Gene
SCN5A
Gene Alias
cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit; CDCD2; CDCD2VF1; CIN5; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; HH1CMD1E; ICCD; IVF; LQT3; LQT3SSS1CMPD2; mH1; Nav1.5; Nav1.5c; PFHB1; RATRSKM2X; RH1; RSkM2; RSKM2X; SCAL; Scn2x; SCN5A; SkM1; SkM2; sodium channel protein cardiac muscle subunit alpha; Sodium channel protein type 5 subunit alpha; sodium channel protein type V subunit alpha; sodium channel voltage-gated type V alpha polypeptide; sodium channel, voltage gated, type V alpha subunit; sodium channel, voltage-gated, type 5, alpha subunit; sodium channel, voltage-gated, type V, alpha; sodium channel, voltage-gated, type V, alpha polypeptide; sodium channel, voltage-gated, type V, alpha subunit; sodium voltage-gated channel alpha subunit 5; SSS1; VF1; voltage-gated sodium channel Nav1.5c; voltage-gated sodium channel subunit alpha Nav1.5
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
6331
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: VSENIKLGNLSALR Purified by Thiophilic Chromatography Scn5a is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit
- Scn5a is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram
- Defects in Scn5a are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease
- Alternative splicing results in several transcript variants encoding different isoforms of Scn5a
- Voltage-gated sodium channesl (VGSCs) mediate regenerative cell membrane depolarization and conduction of electrical signalling in nerves and muscles
- Expression of Scn5a is also detected in lymphocytes, glia, and fibroblasts
- Further, Scn5a mediates the voltage-dependent sodium ion permeability of excitable membranes
- Assuming opened or closed conformations in response to the voltage difference across the membrane, Scn5a forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient
- Functionally, Scn5a is responsible for the initial upstroke of the action potential and the channel inactivation is regulated by intracellular calcium levels
- Voltage-gated sodium channels (NaV) are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types
- Scn5a are also expressed at low levels in non-excitable cells, where their physiological role is unclear
- Diseases associated with SCN5A include Long Qt Syndrome-3 and Brugada Syndrome 1.
Compare Similar Items
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Antigen: SCN5A
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q14524
Gene Symbols: SCN5A
Immunogen: Peptide (14mer) from an extracellular domain of Nav1.5
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Clone: 4G8:1G7
Conjugate: Unconjugated
Gene: SCN5A
Gene Alias: cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit; CDCD2; CDCD2VF1; CIN5; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; HH1CMD1E; ICCD; IVF; LQT3; LQT3SSS1CMPD2; mH1; Nav1.5; Nav1.5c; PFHB1; RATRSKM2X; RH1; RSkM2; RSKM2X; SCAL; Scn2x; SCN5A; SkM1; SkM2; sodium channel protein cardiac muscle subunit alpha; Sodium channel protein type 5 subunit alpha; sodium channel protein type V subunit alpha; sodium channel voltage-gated type V alpha polypeptide; sodium channel, voltage gated, type V alpha subunit; sodium channel, voltage-gated, type 5, alpha subunit; sodium channel, voltage-gated, type V, alpha; sodium channel, voltage-gated, type V, alpha polypeptide; sodium channel, voltage-gated, type V, alpha subunit; sodium voltage-gated channel alpha subunit 5; SSS1; VF1; voltage-gated sodium channel Nav1.5c; voltage-gated sodium channel subunit alpha Nav1.5
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 6331
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SCN5A
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q14524
Gene Symbols:
SCN5A
Immunogen:
Peptide (14mer) from an extracellular domain of Nav1.5
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Clone:
4G8:1G7
Conjugate:
Unconjugated
Gene:
SCN5A
Gene Alias:
cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit; CDCD2; CDCD2VF1; CIN5; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; HH1CMD1E; ICCD; IVF; LQT3; LQT3SSS1CMPD2; mH1; Nav1.5; Nav1.5c; PFHB1; RATRSKM2X; RH1; RSkM2; RSKM2X; SCAL; Scn2x; SCN5A; SkM1; SkM2; sodium channel protein cardiac muscle subunit alpha; Sodium channel protein type 5 subunit alpha; sodium channel protein type V subunit alpha; sodium channel voltage-gated type V alpha polypeptide; sodium channel, voltage gated, type V alpha subunit; sodium channel, voltage-gated, type 5, alpha subunit; sodium channel, voltage-gated, type V, alpha; sodium channel, voltage-gated, type V, alpha polypeptide; sodium channel, voltage-gated, type V, alpha subunit; sodium voltage-gated channel alpha subunit 5; SSS1; VF1; voltage-gated sodium channel Nav1.5c; voltage-gated sodium channel subunit alpha Nav1.5
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
6331
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SCAF11
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q99590
Gene Symbols: SCAF11
Immunogen: Recombinant p30 subunit of mouse SCAF11.
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 17D9
Conjugate: Unconjugated
Gene: SCAF11
Gene Alias: 1110061H03Rik; 17D9; 2610510E10Rik; AI462454; CASP11; Caspase11; Caspase-11; CTD-associated SR protein 11; mKIAA3013; p30 subunit; protein SCAF11; Renal carcinoma antigen NY-REN-40; SC35-interacting protein 1; Scaf11; serine/arginine-rich splicing factor 2, interacting protein; serine/arginine-rich splicing factor 2-interacting protein; SFRS2-interacting protein; SFRS2IP; SIP1; splicing factor, arginine/serine-rich 2, interacting protein; splicing factor, arginine/serine-rich 2-interacting protein; Splicing regulatory protein 129; SR-related and CTD-associated factor 11; SR-related CTD associated factor 11; SR-related CTD-associated factor 11; SRrp129; SRSF2-interacting protein; SRSF2IP
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 312030, 538632, 72193, 9169
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SCAF11
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q99590
Gene Symbols:
SCAF11
Immunogen:
Recombinant p30 subunit of mouse SCAF11.
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
17D9
Conjugate:
Unconjugated
Gene:
SCAF11
Gene Alias:
1110061H03Rik; 17D9; 2610510E10Rik; AI462454; CASP11; Caspase11; Caspase-11; CTD-associated SR protein 11; mKIAA3013; p30 subunit; protein SCAF11; Renal carcinoma antigen NY-REN-40; SC35-interacting protein 1; Scaf11; serine/arginine-rich splicing factor 2, interacting protein; serine/arginine-rich splicing factor 2-interacting protein; SFRS2-interacting protein; SFRS2IP; SIP1; splicing factor, arginine/serine-rich 2, interacting protein; splicing factor, arginine/serine-rich 2-interacting protein; Splicing regulatory protein 129; SR-related and CTD-associated factor 11; SR-related CTD associated factor 11; SR-related CTD-associated factor 11; SRrp129; SRSF2-interacting protein; SRSF2IP
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
312030, 538632, 72193, 9169
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: POLR2D
Classification: Monoclonal
Concentration: __
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: O15514
Gene Symbols: Polr2d
Immunogen: Human recombinant RBP4.
Quantity: 200μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Western Blot
Clone: RB42
Conjugate: Unconjugated
Gene: Polr2d
Gene Alias: 2310002G05Rik; 2610028L19Rik; DNA-directed RNA polymerase II 16 kDa polypeptide; DNA-directed RNA polymerase II subunit D; DNA-directed RNA polymerase II subunit RPB4; HSRBP4; HSRPB4; plasma; POLR2D; polymerase (RNA) II (DNA directed) polypeptide D; polymerase (RNA) II subunit D; RBP4; RNA polymerase II 16 kDa subunit; RNA polymerase II subunit B4; RNA polymerase II subunit D; RNA polymerase II subunit hsRBP4; RPB16
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5433
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
POLR2D
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
O15514
Gene Symbols:
Polr2d
Immunogen:
Human recombinant RBP4.
Quantity:
200μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Western Blot
Clone:
RB42
Conjugate:
Unconjugated
Gene:
Polr2d
Gene Alias:
2310002G05Rik; 2610028L19Rik; DNA-directed RNA polymerase II 16 kDa polypeptide; DNA-directed RNA polymerase II subunit D; DNA-directed RNA polymerase II subunit RPB4; HSRBP4; HSRPB4; plasma; POLR2D; polymerase (RNA) II (DNA directed) polypeptide D; polymerase (RNA) II subunit D; RBP4; RNA polymerase II 16 kDa subunit; RNA polymerase II subunit B4; RNA polymerase II subunit D; RNA polymerase II subunit hsRBP4; RPB16
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5433
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: Thyroid Peroxidase
Classification: Monoclonal
Concentration: 7.9 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P07202
Gene Symbols: TPO
Immunogen: Full length human thyroid peroxidase and spleen cells of Balb/c mice.
Quantity: 250μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Western Blot
Clone: TPO28
Conjugate: Unconjugated
Gene: TPO
Gene Alias: EC 1.11.1; LOW QUALITY PROTEIN: thyroid peroxidase; MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroid peroxidase (332 AA); thyroperoxidase; TPO; TPX; TPXEC 1.11.1.8
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7173
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
Thyroid Peroxidase
Classification:
Monoclonal
Concentration:
7.9 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P07202
Gene Symbols:
TPO
Immunogen:
Full length human thyroid peroxidase and spleen cells of Balb/c mice.
Quantity:
250μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Western Blot
Clone:
TPO28
Conjugate:
Unconjugated
Gene:
TPO
Gene Alias:
EC 1.11.1; LOW QUALITY PROTEIN: thyroid peroxidase; MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroid peroxidase (332 AA); thyroperoxidase; TPO; TPX; TPXEC 1.11.1.8
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7173
Content And Storage:
4° C, do not freeze
Form:
Liquid