PIMA525057

TPMT Monoclonal Antibody (OTI2A2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525057-Each-of-1 In Stock ₹ 50,180.94

PIMA525057 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

TPMT

Classification

Monoclonal

Concentration

0.73 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P51580

Gene Symbols

TPMT

Immunogen

Full length human recombinant protein of TPMT produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2A2

Conjugate

Unconjugated

Gene

TPMT

Gene Alias

AW106912; HGNC:12014; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; Thiopurine S-methyltransferase; TPMT; TPMTD; truncated thiopurine methyltransferase

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7172

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine
  • Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency)
  • TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs
  • These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation
  • Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA525057

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Antigen:
TPMT

Classification:
Monoclonal

Concentration:
0.73 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P51580

Gene Symbols:
TPMT

Immunogen:
Full length human recombinant protein of TPMT produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2A2

Conjugate:
Unconjugated

Gene:
TPMT

Gene Alias:
AW106912; HGNC:12014; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; Thiopurine S-methyltransferase; TPMT; TPMTD; truncated thiopurine methyltransferase

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7172

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PIMA525060

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Antigen:
KIAA1609

Classification:
Monoclonal

Concentration:
0.89 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6P9B6

Gene Symbols:
TLDC1

Immunogen:
Full length human recombinant protein of KIAA1609 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3C4

Conjugate:
Unconjugated

Gene:
TLDC1

Gene Alias:
4632415K11Rik; Kiaa1609; MEAK7; MTOR associated protein, eak-7 homolog; MTOR-associated protein MEAK7; TBC/LysM associated domain containing 1; TBC/LysM-associated domain containing 1; TBC/LysM-associated domain-containing protein 1; TLD domain containing 1; TLD domain-containing protein 1; TLDC1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57707

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PIMA525062

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Antigen:
SIL1

Classification:
Monoclonal

Concentration:
0.53 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H173

Gene Symbols:
SIL1

Immunogen:
Full length human recombinant protein of SIL1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1F9

Conjugate:
Unconjugated

Gene:
SIL1

Gene Alias:
1810057E01Rik; AI042831; BAP; BiP-associated protein; endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae); homolog of yeast; MSS; Nucleotide exchange factor SIL1; SIL1; SIL1 homolog, endoplasmic reticulum chaperone; SIL1 nucleotide exchange factor; SIL1 protein; SIL1-like protein endoplasmic reticulum chaperone; ULG5; UNQ545/PRO836; wz

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64374

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Antigen:
RF1ML

Classification:
Monoclonal

Concentration:
0.6 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UGC7

Gene Symbols:
MTRF1L

Immunogen:
Full length human recombinant protein of MTRF1L produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C8

Conjugate:
Unconjugated

Gene:
MTRF1L

Gene Alias:
9130004K12Rik; HMRF1L; mitochondrial release factor 1 like; mitochondrial translational release factor 1 like; mitochondrial translational release factor 1-like; MRF1L; mtRF1a; MTRF1L; Peptide chain release factor 1-like, mitochondrial

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54516

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid