PIMA525074

TPMT Monoclonal Antibody (OTI4C1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525074-Each-of-1 In Stock ₹ 50,180.94

PIMA525074 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

TPMT

Classification

Monoclonal

Concentration

0.88 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P51580, Q8HX86

Gene Symbols

TPMT

Immunogen

Full length human recombinant protein of TPMT produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4C1

Conjugate

Unconjugated

Gene

TPMT

Gene Alias

AW106912; HGNC:12014; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; Thiopurine S-methyltransferase; TPMT; TPMTD; truncated thiopurine methyltransferase

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

403536, 7172

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine
  • Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency)
  • TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs
  • These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation
  • Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA525074

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Antigen:
TPMT

Classification:
Monoclonal

Concentration:
0.88 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P51580, Q8HX86

Gene Symbols:
TPMT

Immunogen:
Full length human recombinant protein of TPMT produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4C1

Conjugate:
Unconjugated

Gene:
TPMT

Gene Alias:
AW106912; HGNC:12014; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; Thiopurine S-methyltransferase; TPMT; TPMTD; truncated thiopurine methyltransferase

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
403536, 7172

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525075

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Antigen:
RIC8A

Classification:
Monoclonal

Concentration:
0.83 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9NPQ8

Gene Symbols:
RIC8A

Immunogen:
Full length human recombinant protein of RIC8A produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3G3

Conjugate:
Unconjugated

Gene:
RIC8A

Gene Alias:
AI114950; heterotrimeric G protein guanine nucleotide exchange factor Ric-8A; MGC104517; MGC131931; MGC148073; MGC148074; Protein Ric-8A; resistance to inhibitors of cholinesterase 8 homolog; resistance to inhibitors of cholinesterase 8 homolog (C. elegans); resistance to inhibitors of cholinesterase 8 homolog A; resistance to inhibitors of cholinesterase 8A; Ric8; RIC-8; RIC8 guanine nucleotide exchange factor A; RIC8 protein; Ric8a; Ric-8A; synembryn; synembryn-A

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60626

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525079

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Antigen:
NPR3

Classification:
Monoclonal

Concentration:
0.78 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P17342

Gene Symbols:
NPR3

Immunogen:
Full length human recombinant protein of NPR3 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI11H6

Conjugate:
Unconjugated

Gene:
NPR3

Gene Alias:
A NPR-C; ANP-C; ANP-CR; ANPRC; ANPR-C; atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide clearence receptor 3; atrial natriuretic peptide C-type receptor; atrial natriuretic peptide receptor 3; atrial natriuretic peptide receptor 3-like; atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; C5orf23; EF-2; guanylate cyclase C; GUCY2B; lgj; longjohn; natriuretic peptide receptor 3; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); Nppc receptor; Npr3; NPRC; NPR-C; stri; strigosus

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4883

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525080

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Antigen:
NIT1

Classification:
Monoclonal

Concentration:
0.87 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q86X76

Gene Symbols:
NIT1

Immunogen:
Full length human recombinant protein of NIT1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3A11

Conjugate:
Unconjugated

Gene:
NIT1

Gene Alias:
AI255805; Deaminated glutathione amidase; dGSH amidase; ESTM30; MGC57670; Nit1; nitrilase 1; nitrilase homolog 1; rCG_20134; W57327

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4817

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid