PIMA525557

LGR5 Monoclonal Antibody (OTI2H7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525557-Each-of-1 In Stock ₹ 50,266.50

PIMA525557 - Each of 1

₹ 50,266.50

In Stock

Quantity

1

Base Price: ₹ 50,266.50

GST (18%): ₹ 9,047.97

Total Price: ₹ 59,314.47

Antigen

LGR5

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O75473

Gene Symbols

Lgr5

Immunogen

Human recombinant protein fragment corresponding to amino acids 250-550 of LGR5 produced in 293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2H7

Conjugate

Unconjugated

Gene

Lgr5

Gene Alias

Fex; follicle expressed hormone; G protein-coupled receptor 49; GPR49; GPR67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GRP49; HG38; leucine rich repeat containing G protein coupled receptor 5; leucine rich repeat containing G protein-coupled receptor 5; leucine-rich repeat containing G protein-coupled receptor 5; leucine-rich repeat-containing G protein-coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; Lgr5; orphan G protein-coupled receptor HG38; orphan G-protein coupled receptor FEX

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8549

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA525644

--

Img

Thermo Scientific

PIMA525043

--

Img

Thermo Scientific

PIMA525411

--

Img

Thermo Scientific

PIMA525044

--

Img

Thermo Scientific

PIMA525072

--

Img

Thermo Scientific

PIMA525576

--

Img

Thermo Scientific

PIMA525577

--

Img

Thermo Scientific

PIMA525548

--

Description

  • G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord
  • ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This &quoteturn-off&quote activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA525557

--


Antigen:
LGR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75473

Gene Symbols:
Lgr5

Immunogen:
Human recombinant protein fragment corresponding to amino acids 250-550 of LGR5 produced in 293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2H7

Conjugate:
Unconjugated

Gene:
Lgr5

Gene Alias:
Fex; follicle expressed hormone; G protein-coupled receptor 49; GPR49; GPR67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GRP49; HG38; leucine rich repeat containing G protein coupled receptor 5; leucine rich repeat containing G protein-coupled receptor 5; leucine-rich repeat containing G protein-coupled receptor 5; leucine-rich repeat-containing G protein-coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; Lgr5; orphan G protein-coupled receptor HG38; orphan G-protein coupled receptor FEX

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525558

--


Antigen:
FGF21

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9NSA1

Gene Symbols:
FGF21

Immunogen:
Full length human recombinant protein of FGF21 produced in HEK293 cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1H4

Conjugate:
Unconjugated

Gene:
FGF21

Gene Alias:
FGF; FGF21; FGF-21; FGFL; Fibroblast growth factor; Fibroblast growth factor 21; PRO10196; UNQ3115/PRO10196

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26291

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525560

--


Antigen:
BAIAP2

Classification:
Monoclonal

Concentration:
0.65 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UQB8

Gene Symbols:
BAIAP2

Immunogen:
Full length human recombinant protein of BAIAP2 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI 1D9

Conjugate:
Unconjugated

Gene:
BAIAP2

Gene Alias:
BAI1 associated protein 2; BAI1-associated protein 2; BAIAP2; BAI-associated protein 2; BAP2; brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand-associated factor 3; FLAF3; insulin receptor substrate 53; insulin receptor substrate of 53 kDa; insulin receptor substrate p53; insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; insulin receptor tyrosine kinase 53 kDa substrate; Insulin receptor tyrosine kinase substrate protein p53; IRS-58; IRSp53; IRSp53/58; R75030

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10458

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525561

--


Antigen:
beta-4 Tubulin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P04350, Q9D6F9

Gene Symbols:
TUBB4A

Immunogen:
Full length human recombinant protein of TUBB4 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3F1

Conjugate:
Unconjugated

Gene:
TUBB4A

Gene Alias:
AI325297; beta-5; class IVa beta-tubulin; dystonia 4, torsion (autosomal dominant); DYT4; hypothetical protein LOC540236; M(beta)4; QtrA-11757; Tubb; TUBB4; Tubb4a; TUBB5; Tubulin 5 beta; tubulin beta; tubulin beta 4A class IVa; tubulin beta-4 chain; Tubulin beta-4A chain; tubulin, beta 4; tubulin, beta 4 class IVa; tubulin, beta 4A class IVa; tubulin, beta, 5; unnamed protein product

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100855815, 10382, 22153, 29213

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid