PIMA525644

LGR5 Monoclonal Antibody (OTI2A2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525644-Each-of-1 In Stock ₹ 52,876.08

PIMA525644 - Each of 1

₹ 52,876.08

In Stock

Quantity

1

Base Price: ₹ 52,876.08

GST (18%): ₹ 9,517.694

Total Price: ₹ 62,393.774

Antigen

LGR5

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O75473, Q9Z1P4

Gene Symbols

Lgr5

Immunogen

Human recombinant protein fragment corresponding to amino acids 250-550 of LGR5 produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

OTI2A2

Conjugate

Unconjugated

Gene

Lgr5

Gene Alias

Fex; follicle expressed hormone; G protein-coupled receptor 49; GPR49; GPR67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GRP49; HG38; leucine rich repeat containing G protein coupled receptor 5; leucine rich repeat containing G protein-coupled receptor 5; leucine-rich repeat containing G protein-coupled receptor 5; leucine-rich repeat-containing G protein-coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; Lgr5; orphan G protein-coupled receptor HG38; orphan G-protein coupled receptor FEX

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14160, 8549

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord
  • ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This &quoteturn-off&quote activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA525644

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Antigen:
LGR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75473, Q9Z1P4

Gene Symbols:
Lgr5

Immunogen:
Human recombinant protein fragment corresponding to amino acids 250-550 of LGR5 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
OTI2A2

Conjugate:
Unconjugated

Gene:
Lgr5

Gene Alias:
Fex; follicle expressed hormone; G protein-coupled receptor 49; GPR49; GPR67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GRP49; HG38; leucine rich repeat containing G protein coupled receptor 5; leucine rich repeat containing G protein-coupled receptor 5; leucine-rich repeat containing G protein-coupled receptor 5; leucine-rich repeat-containing G protein-coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; Lgr5; orphan G protein-coupled receptor HG38; orphan G-protein coupled receptor FEX

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525645

--


Antigen:
HSPBP1

Classification:
Monoclonal

Concentration:
0.43 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9NZL4

Gene Symbols:
HSPBP1

Immunogen:
Full length human recombinant protein of HSPBP1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
OTI1H4

Conjugate:
Unconjugated

Gene:
HSPBP1

Gene Alias:
1500019G21Rik; FES1; Heat shock protein; heat shock protein-binding protein 1; HSP; hsp70 interacting protein; hsp70-binding protein 1; Hsp70-binding protein 2; hsp70-interacting protein; hsp70-interacting protein 1; Hsp70-interacting protein 2; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; HSPA (Hsp70) binding protein 1; HSPA binding protein, cytoplasmic cochaperone 1; Hspbp; HSPBP1; HspBP2; LOW QUALITY PROTEIN: hsp70-binding protein 1; MGC128574 protein; PP1845; SPA ) binding protein, cytoplasmic cochaperone 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23640

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525649

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Antigen:
PDE1B

Classification:
Monoclonal

Concentration:
0.95 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q01064, Q01066

Gene Symbols:
Pde1b

Immunogen:
Full length human recombinant protein of PDE1B produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
OTI6B9

Conjugate:
Unconjugated

Gene:
Pde1b

Gene Alias:
63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; Aop2; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); EGK_03739; epididymis secretory sperm binding protein Li 79p; HEL-S-79p; PDE 1B; Pde1b; Pde1b1; PDES 1B; PDES1B; Phosphodiesterase; phosphodiesterase 1B; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent; phosphodiesterase 1B, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase 1B, calmodulin-dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100856025, 29691, 5153

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA525650

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Antigen:
NEK9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8TD19

Gene Symbols:
NEK9

Immunogen:
Full length human recombinant protein of NEK9 produced in HEK293 cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
OTI1H1

Conjugate:
Unconjugated

Gene:
NEK9

Gene Alias:
APUG; C130021H08Rik; DKFZp434D0935; KIAA1995; LCCS10; MGC138306; MGC16714; NC; NEK 9; NEK8; NEK9; Nercc; Nercc 1 kinase; NERCC1; Nercc1 kinase; never in mitosis A-related kinase 9; NIMA (never in mitosis gene a)- related kinase 9; NIMA (never in mitosis gene a)-related expressed kinase 9; NIMA related kinase 9; NimA-related kinase 8; NIMA-related kinase 9; nimA-related protein kinase 9; Serine/threonine-protein kinase Nek9

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
91754

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid