GNAS Monoclonal Antibody (OTI7A6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527115-Each-of-1 | In Stock | ₹ 53,303.88 |
PIMA527115 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,303.88
GST (18%): ₹ 9,594.698
Total Price: ₹ 62,898.578
Antigen
GNAS
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O95467, P63092, P63094, P84996, Q5JWF2, Q63803, Q6R0H6, Q6R0H7, Q9Z0F1
Gene Symbols
GNAS
Immunogen
Full length human recombinant protein of GNAS produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI7A6
Conjugate
Unconjugated
Gene
GNAS
Gene Alias
5530400H20Rik; A930027G11Rik; Adenylate cyclase-stimulating G alpha protein; AHO; ALEX; GNAS; NESP55; alpha-stimulatory subunit of GTP-binding protein; alternative gene product encoded by XL-exon; C130027O20Rik; C20orf45; dJ309F20.1.1; dJ806M20.3.3; Extra large alphas protein; G protein alpha subunit; G protein subunit alpha S; GAIPIRRH peptide; G-alpha-8; Galphas; Gnas; GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus; gnas {ECO:0000312; GNAS complex locus; GNAS complex locus; SCG6 (secretogranin VI); GNAS1; Gnasxl; Gnpas; GPIPIRRH peptide; GPSA; Gs alpha subunit; GSA; G-SALPHA60A; GSP; GTP-binding regulatory protein (G-s-alpha).; GTP-binding regulatory protein alpha subunit exon 1; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1; guanine nucleotide binding protein alpha s; guanine nucleotide binding protein alpha subunit; guanine nucleotide binding protein, alpha stimulating activity polypeptide 1; guanine nucleotide regulatory protein; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; SCG6 (secretogranin VI); guanine nucleotide-binding protein G(s), alpha subunit; guanine nucleotide-binding protein Gs alpha1; guanine nucleotide-binding protein G-s, alpha subunit; guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1; LHAL tetrapeptide; LSAL tetrapeptide; MGC33735; MNCb-5546; Nesp; NESP55; Nespl; neuroendocrine secretory protein; neuroendocrine secretory protein 55; Oedsml; Oed-Sml; OTTHUMP00000031742; OTTHUMP00000196026; OTTHUMP00000196030; P1; P2; P3; PHP1A; PHP1B; PHP1C; POH; PORGSA1; Protein ALEX; protein ALEX; protein GNAS; protein NESP55; protein ALEX; protein GNAS; protein SCG6 (secretogranin VI); RGD:2716}; RP4-543J19.4; SCG6; secretogranin VI; SgVI; stimulatory G-protein alpha subunit; stimulatory GTP binding protein; unnamed protein product; XLalphas; XLas
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14683, 24896, 2778
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Mutations in GNAS gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseous heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors
- This gene has a highly complex imprinted expression pattern
- It encodes maternally, paternally, and biallelically expressed proteins which are derived from alternatively spliced transcripts with alternate 5' exons
- Each of the upstream exons is within a differentially methylated region, commonly found in imprinted genes
- However, the close proximity (14 kb) of two oppositely expressed promoter regions is unusual
- In addition, one of the alternate 5' exons introduces a frameshift relative to the other transcripts, resulting in one isoform which is structurally unrelated to the others
- An antisense transcript exists, and may regulate imprinting in this region
- Mutations in this gene result in pseudohypoparathyroidism type 1a (PHP1a), which has an atypical autosomal dominant inheritance pattern requiring maternal transmission for full penetrance.
Compare Similar Items
Show Difference
Antigen: GNAS
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O95467, P63092, P63094, P84996, Q5JWF2, Q63803, Q6R0H6, Q6R0H7, Q9Z0F1
Gene Symbols: GNAS
Immunogen: Full length human recombinant protein of GNAS produced in HEK293T cell
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI7A6
Conjugate: Unconjugated
Gene: GNAS
Gene Alias: 5530400H20Rik; A930027G11Rik; Adenylate cyclase-stimulating G alpha protein; AHO; ALEX; GNAS; NESP55; alpha-stimulatory subunit of GTP-binding protein; alternative gene product encoded by XL-exon; C130027O20Rik; C20orf45; dJ309F20.1.1; dJ806M20.3.3; Extra large alphas protein; G protein alpha subunit; G protein subunit alpha S; GAIPIRRH peptide; G-alpha-8; Galphas; Gnas; GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus; gnas {ECO:0000312; GNAS complex locus; GNAS complex locus; SCG6 (secretogranin VI); GNAS1; Gnasxl; Gnpas; GPIPIRRH peptide; GPSA; Gs alpha subunit; GSA; G-SALPHA60A; GSP; GTP-binding regulatory protein (G-s-alpha).; GTP-binding regulatory protein alpha subunit exon 1; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1; guanine nucleotide binding protein alpha s; guanine nucleotide binding protein alpha subunit; guanine nucleotide binding protein, alpha stimulating activity polypeptide 1; guanine nucleotide regulatory protein; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; guanine nucleotide-binding protein G(s) subunit alpha; SCG6 (secretogranin VI); guanine nucleotide-binding protein G(s), alpha subunit; guanine nucleotide-binding protein Gs alpha1; guanine nucleotide-binding protein G-s, alpha subunit; guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1; LHAL tetrapeptide; LSAL tetrapeptide; MGC33735; MNCb-5546; Nesp; NESP55; Nespl; neuroendocrine secretory protein; neuroendocrine secretory protein 55; Oedsml; Oed-Sml; OTTHUMP00000031742; OTTHUMP00000196026; OTTHUMP00000196030; P1; P2; P3; PHP1A; PHP1B; PHP1C; POH; PORGSA1; Protein ALEX; protein ALEX; protein GNAS; protein NESP55; protein ALEX; protein GNAS; protein SCG6 (secretogranin VI); RGD:2716}; RP4-543J19.4; SCG6; secretogranin VI; SgVI; stimulatory G-protein alpha subunit; stimulatory GTP binding protein; unnamed protein product; XLalphas; XLas
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14683, 24896, 2778
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen: GRB7
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q14451
Gene Symbols: GRB7
Immunogen: Full length human recombinant protein of GRB7 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI6H2
Conjugate: Unconjugated
Gene: GRB7
Gene Alias: B47; Epidermal growth factor receptor GRB-7; Grb7; GRB7 adapter protein; growth factor receptor binding protein GRB7; growth factor receptor bound protein 7; growth factor receptor-bound protein 7; Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7); mKIAA4028; OTTHUMP00000164352
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2886
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen: FXR
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q96RI1
Gene Symbols: NR1H4
Immunogen: Human recombinant protein fragment corresponding to amino acids 21-297 of NR1H4 produced in E.coli
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: OTI4F12
Conjugate: Unconjugated
Gene: NR1H4
Gene Alias: AI957360; BAR; bile acid receptor; farnesoid X activated receptor; farnesoid X nuclear receptor; farnesoid X-activated receptor; Farnesol receptor HRR-1; FXR; HRR1; HRR-1; hypothetical protein LOC540528; MGC163445; NR1H4; Nuclear receptor subfamily 1 group H member 4; nuclear receptor subfamily 1, group H, member 4; retinoid X receptor-interacting protein 14; RIP14; RXR-interacting protein 14; Rxrip14
Host Species: Mouse
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9971
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
