PIMA527584

DUX4 Monoclonal Antibody (P2B1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527584-Each-of-1 In Stock ₹ 50,180.94

PIMA527584 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

DUX4

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

Q9UBX2

Gene Symbols

Dux4

Immunogen

C-terminal 76 amino acids of human DUX4 with glutathione-s-transferase (gst) tag

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

P2B1

Conjugate

Unconjugated

Gene

Dux4

Gene Alias

AW822073; double homeobox; double homeobox 4; double homeobox 4-like; double homeobox B-like 1; double homeobox protein 10; Double homeobox protein 4; double homeobox protein 4/10; Dux; DUX10; Dux4; DUX4L; Duxbl; Duxbl1; EG664783; homeobox protein; RGD1311053

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100288687

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA527710

--

Img

Thermo Scientific

PIMA527685

--

Img

Thermo Scientific

PIMA527723

--

Img

Thermo Scientific

PIMA527603

--

Img

Thermo Scientific

PIMA527976

--

Img

Thermo Scientific

PIMA527585

--

Img

Thermo Scientific

PIMA527553

--

Img

Thermo Scientific

PIMA527611

--

Description

  • 1 μg/mL of MA5-27584 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.∣Detects approximately 45kDa
  • No cross-reactivity with DUX4c
  • DUX4 (also known as Double homeobox 4) is the leading candidate causative gene for facioscapulohumeral dystrophy (FSHD), a degenerative skeletal muscle disease and one of the most common muscular dystrophies
  • FSHD is caused by the deletion of a subset of D4Z4 macrosatellite repeats on chromosome 4
  • Each repeat contains a retrogene encoding the double-homeobox factor DUX4
  • DUX4 expression is epigenetically suppressed in differentiated tissues and the residual DUX4 transcripts are spliced to remove the carboxyterminal domain that has been associated with cell toxicity
  • In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle, and possibly other differentiated tissues, and results in a small percentage of cells expressing relatively abundant amounts of the full-length DUX4 mRNA and protein.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527584

--


Antigen:
DUX4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9UBX2

Gene Symbols:
Dux4

Immunogen:
C-terminal 76 amino acids of human DUX4 with glutathione-s-transferase (gst) tag

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
P2B1

Conjugate:
Unconjugated

Gene:
Dux4

Gene Alias:
AW822073; double homeobox; double homeobox 4; double homeobox 4-like; double homeobox B-like 1; double homeobox protein 10; Double homeobox protein 4; double homeobox protein 4/10; Dux; DUX10; Dux4; DUX4L; Duxbl; Duxbl1; EG664783; homeobox protein; RGD1311053

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100288687

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527585

--


Antigen:
NLGN4X

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
B0F2B4

Gene Symbols:
Nlgn4l

Immunogen:
Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ∽45% identity with Neuroligin-1, -2 and -3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
S98-7

Conjugate:
Unconjugated

Gene:
Nlgn4l

Gene Alias:
ASPGX2; AUTSX2; HLNX; HNL4X; HNLX; KIAA1260; MGC22376; neuroligin 4, X-linked; neuroligin 4-like; Neuroligin X; Neuroligin-4, X-linked; NL4; NL-4; NLGN; Nlgn4; Nlgn4l; NLGN4X; UNQ365/PRO701

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100113365

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527586

--


Antigen:
Metallothionein

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
PA2140

Immunogen:
Full length Pseudomonas aeruginosa Metallothionein protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
2B5

Conjugate:
Unconjugated

Gene:
PA2140

Gene Alias:
Metallothionein; Metallothionein-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
880550

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527589

--


Antigen:
HCN1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
O60741, O88704, Q9JKB0

Gene Symbols:
HCN1

Immunogen:
Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
S70-28

Conjugate:
Unconjugated

Gene:
HCN1

Gene Alias:
Bcng1; BCNG-1; Brain cyclic nucleotide-gated channel 1; C630013B14Rik; EIEE24; Hac2; HAC-2; Hcn1; hyperpolarization activated cyclic nucleotide gated potassium channel 1; hyperpolarization-activated cation channel 2; hyperpolarization-activated cyclic nucleotide-gated potassium channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15165, 348980, 84390

Content And Storage:
-20°C

Form:
Liquid