PIMA527589

HCN1 Monoclonal Antibody (S70-28), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA527589-Each-of-1 In Stock ₹ 50,180.94

PIMA527589 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

HCN1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

O60741, O88704, Q9JKB0

Gene Symbols

HCN1

Immunogen

Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Microarray, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

S70-28

Conjugate

Unconjugated

Gene

HCN1

Gene Alias

Bcng1; BCNG-1; Brain cyclic nucleotide-gated channel 1; C630013B14Rik; EIEE24; Hac2; HAC-2; Hcn1; hyperpolarization activated cyclic nucleotide gated potassium channel 1; hyperpolarization-activated cation channel 2; hyperpolarization-activated cyclic nucleotide-gated potassium channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

15165, 348980, 84390

Content And Storage

-20°C

Form

Liquid

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Description

  • 1 μg/mL of MA5-27589 was sufficient for detection of HCN1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 100kDa
  • No cross-reactivity against HCN2
  • HCN1 includes Hyperpolarization-activated cation channels of the HCN gene family, which contribute to spontaneous rhythmic activity in both heart and brain
  • HCN1 is a member of a family of pacemaker channels activated by hyperpolarization and regulated by cyclic nucleotides
  • HCN1 and HCN2 play an important role for motor learning and neuronal integration by cerebellar Purkinje cells as well as, shaping autonomous activity of single neurons and the periodicity of network oscillations
  • The HCN1 expression is highly enriched in cerebral cortex, hippocampus, cerebellum, and facial motor nucleus
  • HCN2 is highly abundant in mamillary bodies, pontine nucleus, ventral cochlear nucleus, and nucleus of the trapezoid body
  • These variations in regional specificity of HCN channels could generate important differences in neuronal pacemaker activity across brain systems.

Compare Similar Items

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Img

Thermo Scientific

PIMA527589

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Antigen:
HCN1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
O60741, O88704, Q9JKB0

Gene Symbols:
HCN1

Immunogen:
Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
S70-28

Conjugate:
Unconjugated

Gene:
HCN1

Gene Alias:
Bcng1; BCNG-1; Brain cyclic nucleotide-gated channel 1; C630013B14Rik; EIEE24; Hac2; HAC-2; Hcn1; hyperpolarization activated cyclic nucleotide gated potassium channel 1; hyperpolarization-activated cation channel 2; hyperpolarization-activated cyclic nucleotide-gated potassium channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 1; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15165, 348980, 84390

Content And Storage:
-20°C

Form:
Liquid

Img

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PIMA527592

--


Antigen:
NPAS4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q8BGD7, Q8CJH6, Q8IUM7

Gene Symbols:
NPAS4

Immunogen:
Fusion protein amino acids 597-802 (C-terminus) of rat Npas4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S408-79

Conjugate:
Unconjugated

Gene:
NPAS4

Gene Alias:
bHLH PAS type transcription factor NXF; bHLHe79; bHLH-PAS type transcription factor NXF; Class E basic helix-loop-helix protein 79; HLH-PAS transcription factor NXF; LE-PAS; Limbic-enhanced PAS protein; neuronal PAS domain protein 4; neuronal PAS domain-containing protein 4; Neuronal PAS4; Npas4; NXF; PAS domain-containing protein 10; PASD10; PASD10 and LE-PAS

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
225872, 266734, 266743

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527593

--


Antigen:
NALCN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q6Q760, Q8BXR5, Q8IZF0

Gene Symbols:
NALCN

Immunogen:
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
S187-7

Conjugate:
Unconjugated

Gene:
NALCN

Gene Alias:
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
259232, 266760, 338370

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527597

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Antigen:
TRPV3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q8K424, Q8NET8

Gene Symbols:
TRPV3

Immunogen:
Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
N15/39

Conjugate:
Unconjugated

Gene:
TRPV3

Gene Alias:
1110036I10Rik; AI644701; FNEPPK2; heat sensitive channel TRPV3; MGC124324; MGC124325; Nh; non-hair; OLMS; Transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel, subfamily V, member 3; TRP ion channel TRPV3; TrpV3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; VRL 3; VRL3; VRL-3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
162514, 246788, 497948

Content And Storage:
-20°C

Form:
Liquid