PIMA527718

HCN2 Monoclonal Antibody (S71), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA527718-Each-of-1 In Stock ₹ 50,608.74

PIMA527718 - Each of 1

₹ 50,608.74

In Stock

Quantity

1

Base Price: ₹ 50,608.74

GST (18%): ₹ 9,109.573

Total Price: ₹ 59,718.313

Antigen

HCN2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

O88703, Q9JKA9, Q9UL51

Gene Symbols

HCN2

Immunogen

Fusion protein amino acids 761-863 of rat HCN2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

S71

Conjugate

Unconjugated

Gene

HCN2

Gene Alias

BCNG2; BCNG-2; brain cyclic nucleotide gated channel 2; brain cyclic nucleotide-gated channel 2; Hac1; HAC-1; HCN2; hyperpolarization activated cyclic nucleotide gated potassium channel 2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; hyperpolarization-activated cation channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; trls

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

114244, 15166, 610

Content And Storage

-20°C

Form

Liquid

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Description

  • 1 μg/mL of MA5-27718 was sufficient for detection of HCN2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 95kDa
  • No cross-reactivity against HCN1
  • Hyperpolarization-activated cation channels of the HCN gene family such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain
  • HCN2 is a member of a family of pacemaker channels activated by hyperpolarization and regulated by cyclic nucleotides
  • HCN1 and HCN2 play an important role for motor learning and neuronal integration by cerebellar Purkinje cells; as well as, shaping autonomous activity of single neurons and the periodicity of network oscillations
  • The HCN1 expression is highly enriched in cerebral cortex, hippocampus, cerebellum, and facial motor nucleus
  • HCN2 is highly abundant in mamillary bodies, pontine nucleus, ventral cochlear nucleus, and nucleus of the trapezoid body
  • These variations in regional specificity of HCN channels could generate important differences in neuronal pacemaker activity across brain systems.

Compare Similar Items

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Img

Thermo Scientific

PIMA527718

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Antigen:
HCN2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
O88703, Q9JKA9, Q9UL51

Gene Symbols:
HCN2

Immunogen:
Fusion protein amino acids 761-863 of rat HCN2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
S71

Conjugate:
Unconjugated

Gene:
HCN2

Gene Alias:
BCNG2; BCNG-2; brain cyclic nucleotide gated channel 2; brain cyclic nucleotide-gated channel 2; Hac1; HAC-1; HCN2; hyperpolarization activated cyclic nucleotide gated potassium channel 2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; hyperpolarization-activated cation channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; trls

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114244, 15166, 610

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527719

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Antigen:
ATP7B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P35670, Q64446, Q64535

Gene Symbols:
Atp7b

Immunogen:
Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
S62-29

Conjugate:
Unconjugated

Gene:
Atp7b

Gene Alias:
Atp7a; ATP7B; ATPase copper transporting beta; ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease); copper pump 2; Copper-transporting ATPase 2; Hts; PINA; PINA gene, promoter; pineal night-specific ATPase; PWD; RP11-327P2.1; RP11-327P2.3; toxic milk; tx; WC1; WD; Wilson disease-associated protein; wilson disease-associated protein homolog; Wilson protein; Wnd; WND/140 kDa

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11979, 24218, 540

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527720

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Antigen:
ATP7A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P70705, Q04656, Q64430

Gene Symbols:
ATP7A

Immunogen:
Synthetic peptide amino acids 42-61 (cytoplasmic C-terminus) of human Copper- transporting ATPase1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
S60-4

Conjugate:
Unconjugated

Gene:
ATP7A

Gene Alias:
ATP 7A; ATP7A; ATPase copper transporting alpha; ATPase, Cu++ transporting, alpha polypeptide; copper pump 1; Copper-transporting ATPase 1; Cu++-transporting P-type ATPase; DSMAX; FLJ17790; MC 1; MC1; Menke; Menkes disease-associated protein; menkes disease-associated protein homolog; Menkes protein; Menkes syndrome; MK; MNK; OHS; OTTHUMP00000062077; SMAX3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11977, 24941, 538

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527721

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Antigen:
ATF4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P18848, Q06507, Q9ES19

Gene Symbols:
Atf4

Immunogen:
Fusion protein amino acids 25-327 of human ATF4. 86% identical to rat, and 85% identical to mouse. <50% identity with ATF5.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S360A-24

Conjugate:
Unconjugated

Gene:
Atf4

Gene Alias:
Activating transcription factor 4; activating transcription factor 4 (tax-responsive enhancer element B67); activating transcription factor 4a; activating transcription factor 4b1 (tax-responsive enhancer element B67); activating transcription factor ATF-4; ATF 4; atf4; Atf-4; atf4 {ECO:0000312; ATF4 protein; atf4a; atf4b1; C/ATF; C/EBP-related ATF; cAMP response element-binding protein 2; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB 2; CREB2; CREB-2; Cyclic AMP-dependent transcription factor ATF-4; cyclic AMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; hypothetical protein LOC509107; OTTHUMP00000199130; rATF-4; RGD:621863}; tax-re; TaxREB67; TaxREB67 homolog; tax-responsive enhancer element B67; tax-responsive enhancer element-binding protein 67; Tax-responsive enhancer element-binding protein 67 homolog; TXREB; wu:fj01c08; wu:fk30b04; zgc:85951

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11911, 468, 79255

Content And Storage:
-20°C

Form:
Liquid