PIMA527593
NALCN Monoclonal Antibody (S187-7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527593-Each-of-1 | In Stock | ₹ 50,523.18 |
PIMA527593 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,523.18
GST (18%): ₹ 9,094.172
Total Price: ₹ 59,617.352
Antigen
NALCN
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.
Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols
NALCN
Immunogen
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Western Blot
Clone
S187-7
Conjugate
Unconjugated
Gene
NALCN
Gene Alias
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
259232, 266760, 338370
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- 1 μg/mL of MA5-27593 was sufficient for detection of NALCN in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 200kDa
- Nalcn is a voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions
- Nalcn regulates the resting membrane potential and controls neuronal excitability (PubMed:17448995)
- Neuropeptides such as neurotensin and substance P (SP) stimulate the firing of action potentials by activating NALCN through a SRC family kinases-dependent pathway
- In addition to its baseline activity, Nalcn activity is enhanced/modulated by several GPCRs, is required for normal respiratory rhythm and neonatal survival, is involved in systemic osmoregulation by controlling the serum sodium concentration
- Nalcn is partly responsible for the substance P-induced depolarization and regulation of the intestinal pace-making activity in the interstitial cells of Cajal
- Further, Nalcn plays a critical role in both maintenance of spontaneous firing of substantia nigra pars reticulata (SNr) neurons and physiological modulation of SNr neuron excitability
- Diseases associated with NALCN include Congenital contractures of the limbs and face, Hypotonia, Developmental Delay and Hypotonia, Infantile Psychomotor Retardation And Characteristic Facies 1.
Compare Similar Items
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Antigen: NALCN
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols: NALCN
Immunogen: Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: S187-7
Conjugate: Unconjugated
Gene: NALCN
Gene Alias: A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 259232, 266760, 338370
Content And Storage: -20°C
Form: Liquid
Antigen:
NALCN
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q6Q760, Q8BXR5, Q8IZF0
Gene Symbols:
NALCN
Immunogen:
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
S187-7
Conjugate:
Unconjugated
Gene:
NALCN
Gene Alias:
A530023G15Rik; AI849508; bA430M15.1; brain voltage-gated cation channel; CanIon; CLIFAHDD; FLJ23913; FLJ44659; FLJ44764; Four domain-type voltage-gated ion channel alpha-1 subunit; four repeat voltage-gated ion channel; IHPRF; IHPRF1; INNFD; MGC74524; Nalcn; Nca; Rb21; Rb21-channel; Sodium leak channel non-selective protein; sodium leak channel, non selective; sodium leak channel, non-selective; Vgcnl1; voltage gated channel like 1; voltage gated channel-like protein 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
259232, 266760, 338370
Content And Storage:
-20°C
Form:
Liquid
Antigen: TRPV3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q8K424, Q8NET8
Gene Symbols: TRPV3
Immunogen: Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: N15/39
Conjugate: Unconjugated
Gene: TRPV3
Gene Alias: 1110036I10Rik; AI644701; FNEPPK2; heat sensitive channel TRPV3; MGC124324; MGC124325; Nh; non-hair; OLMS; Transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel, subfamily V, member 3; TRP ion channel TRPV3; TrpV3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; VRL 3; VRL3; VRL-3
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 162514, 246788, 497948
Content And Storage: -20°C
Form: Liquid
Antigen:
TRPV3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q8K424, Q8NET8
Gene Symbols:
TRPV3
Immunogen:
Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
N15/39
Conjugate:
Unconjugated
Gene:
TRPV3
Gene Alias:
1110036I10Rik; AI644701; FNEPPK2; heat sensitive channel TRPV3; MGC124324; MGC124325; Nh; non-hair; OLMS; Transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel, subfamily V, member 3; TRP ion channel TRPV3; TrpV3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; VRL 3; VRL3; VRL-3
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
162514, 246788, 497948
Content And Storage:
-20°C
Form:
Liquid
Antigen: SHANK3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
Gene Accession No.: Q4ACU6, Q9BYB0, Q9JLU4
Gene Symbols: Shank3
Immunogen: Fusion protein amino acids 538-626 (SH3 domain) of rat SHANK3. Mouse: 100% identity (89/89 amino acids identical). Human: 97% identity (87/89 amino acids identical). ∽70% identity with SHANK1 and SHANK2.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Clone: S367-51
Conjugate: Unconjugated
Gene: Shank3
Gene Alias: AI841104; DEL22q13.3; Kiaa1650; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat domains-like protein 3 variant 2; SH3 and multiple ankyrin repeat domains-like protein 3 variant 3; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-3; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-2; SH3/ankyrin domain gene 3; shank postsynaptic density protein; Shank postsynaptic density protein 3a; SHANK3; shank3 splice variant II; shank3 splice variant III; shank3 splice variant IV; Shank3b; SHANK3c-3; SHANK3c-4; shank3e splice variant III; shank3e splice variant IV; SPANK 2; SPANK2; SPANK-2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 58234, 59312, 85358
Content And Storage: -20°C
Form: Liquid
Antigen:
SHANK3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
Gene Accession No.:
Q4ACU6, Q9BYB0, Q9JLU4
Gene Symbols:
Shank3
Immunogen:
Fusion protein amino acids 538-626 (SH3 domain) of rat SHANK3. Mouse: 100% identity (89/89 amino acids identical). Human: 97% identity (87/89 amino acids identical). ∽70% identity with SHANK1 and SHANK2.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Clone:
S367-51
Conjugate:
Unconjugated
Gene:
Shank3
Gene Alias:
AI841104; DEL22q13.3; Kiaa1650; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat domains-like protein 3 variant 2; SH3 and multiple ankyrin repeat domains-like protein 3 variant 3; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-3; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-2; SH3/ankyrin domain gene 3; shank postsynaptic density protein; Shank postsynaptic density protein 3a; SHANK3; shank3 splice variant II; shank3 splice variant III; shank3 splice variant IV; Shank3b; SHANK3c-3; SHANK3c-4; shank3e splice variant III; shank3e splice variant IV; SPANK 2; SPANK2; SPANK-2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
58234, 59312, 85358
Content And Storage:
-20°C
Form:
Liquid
Antigen: ATAD1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q505J9, Q8NBU5, Q9D5T0
Gene Symbols: ATAD1
Immunogen: Fusion protein amino acids 1-361 (Full length) of mouse Thorase
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: S125-10
Conjugate: Unconjugated
Gene: ATAD1
Gene Alias: 4921525H23Rik; AAA+ ATPase Thorase; Ab2-088; AFDC1; Atad1; ATPase family AAA domain containing 1; ATPase family AAA domain-containing protein 1; ATPase family, AAA domain containing 1; ATPase Thorase; AW107648; FLJ14600; FNP001; neuroprotective protein 6; Npg6; Thorase
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 309532, 67979, 84896
Content And Storage: -20°C
Form: Liquid
Antigen:
ATAD1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q505J9, Q8NBU5, Q9D5T0
Gene Symbols:
ATAD1
Immunogen:
Fusion protein amino acids 1-361 (Full length) of mouse Thorase
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
S125-10
Conjugate:
Unconjugated
Gene:
ATAD1
Gene Alias:
4921525H23Rik; AAA+ ATPase Thorase; Ab2-088; AFDC1; Atad1; ATPase family AAA domain containing 1; ATPase family AAA domain-containing protein 1; ATPase family, AAA domain containing 1; ATPase Thorase; AW107648; FLJ14600; FNP001; neuroprotective protein 6; Npg6; Thorase
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
309532, 67979, 84896
Content And Storage:
-20°C
Form:
Liquid