PIMA527688
HSF1 Monoclonal Antibody (10H8), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527688-Each-of-1 | In Stock | ₹ 50,266.50 |
PIMA527688 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,266.50
GST (18%): ₹ 9,047.97
Total Price: ₹ 59,314.47
Antigen
HSF1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.
P38532, Q00613, Q08DJ8
Gene Symbols
Hsf1
Immunogen
Purified recombinant mouse HSF1 protein, with epitope mapping to amino acids 378-395
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Gel Shift, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation
Clone
10H8
Conjugate
Unconjugated
Gene
Hsf1
Gene Alias
AA960185; heat shock factor 1; heat shock factor 2; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100350887, 100762942, 101787582, 15499, 3297, 506235, 714078, 79245
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- 1 μg/mL of MA5-27688 was sufficient for detection of HSF1 in 20 μg of heat shocked HeLa cell lysate by ECL immunoblot analysis using Goat anti-rat IgG: HRP as the secondary antibody∣Detects approximately 85kDa (unstressed cell lysates), andapproximately 95kDa (heat shocked cell lysates)
- All organisms respond to elevated temperatures and a variety of environmental stresses by rapid synthesis of heat shock RNAs and proteins
- The regulation of heat shock gene transcription is mediated by the transcriptional activator, heat shock factor (HSF), which binds to heat shock response elements (HSEs)
- These HSEs are found as three repeats of a 5-nucleotide {nGAAn} module, arranged in alternating orientation and present upstream of all heat shock genes
- The HSEs are highly conserved among species yet HSF purified from yeast, Drosophila and human have different molecular weights and the proteins do not show significant immunological cross reaction
- Two HSFs have been identified in human cells, HSF1 and HSF2, which bind to the same HSEs and have 38% sequence identity
- These factors are activated by distinct stimuli, HSF1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF2 is activated during hemin-mediated differentiation of human erythroleukemia cells
- HSF1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity
- Through an unknown signal generated during stress, HSF1 becomes activated to a nuclear localized, trimeric state which binds to DNA
- The phosphorylation of HSF1 is necessary for maximal transcription of heat shock genes.
Compare Similar Items
Show Difference
Antigen: HSF1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P38532, Q00613, Q08DJ8
Gene Symbols: Hsf1
Immunogen: Purified recombinant mouse HSF1 protein, with epitope mapping to amino acids 378-395
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Gel Shift, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation
Clone: 10H8
Conjugate: Unconjugated
Gene: Hsf1
Gene Alias: AA960185; heat shock factor 1; heat shock factor 2; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100350887, 100762942, 101787582, 15499, 3297, 506235, 714078, 79245
Content And Storage: -20°C
Form: Liquid
Antigen:
HSF1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P38532, Q00613, Q08DJ8
Gene Symbols:
Hsf1
Immunogen:
Purified recombinant mouse HSF1 protein, with epitope mapping to amino acids 378-395
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Gel Shift, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation
Clone:
10H8
Conjugate:
Unconjugated
Gene:
Hsf1
Gene Alias:
AA960185; heat shock factor 1; heat shock factor 2; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100350887, 100762942, 101787582, 15499, 3297, 506235, 714078, 79245
Content And Storage:
-20°C
Form:
Liquid
Antigen: ERp57
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P30101
Gene Symbols: PDIA3
Immunogen: Human recombinant ERp57 (Grp58) protein corresponding to amino acids 25 - 505 (his-tagged)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Western Blot
Clone: 4F9
Conjugate: Unconjugated
Gene: PDIA3
Gene Alias: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; 58kDa; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER60; ER-60 protease; Erp; ERp 57; ERp57; ERP57 protein; ERP60; ERp61; glucose regulated protein 58; glucose regulated protein 58kD; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; GRP57; Grp58; grp-58; HEL-S-269; HEL-S-93n; HIP-70; HsT17083; I79_003765; oxidoreductase ERp57; p58; PDI; PDIA 3; PDIA3; PDI-Q2; phospholipase C, alpha; phospholipase C-alpha; PI PLC; PI-PLC; PLC alpha; PLC[a]; Plca; protein disulfide isomerase associated 3; protein disulfide isomerase family A member 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide-iso
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2923
Content And Storage: -20°C
Form: Liquid
Antigen:
ERp57
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P30101
Gene Symbols:
PDIA3
Immunogen:
Human recombinant ERp57 (Grp58) protein corresponding to amino acids 25 - 505 (his-tagged)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Western Blot
Clone:
4F9
Conjugate:
Unconjugated
Gene:
PDIA3
Gene Alias:
58 kDa glucose-regulated protein; 58 kDa microsomal protein; 58kDa; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER60; ER-60 protease; Erp; ERp 57; ERp57; ERP57 protein; ERP60; ERp61; glucose regulated protein 58; glucose regulated protein 58kD; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; GRP57; Grp58; grp-58; HEL-S-269; HEL-S-93n; HIP-70; HsT17083; I79_003765; oxidoreductase ERp57; p58; PDI; PDIA 3; PDIA3; PDI-Q2; phospholipase C, alpha; phospholipase C-alpha; PI PLC; PI-PLC; PLC alpha; PLC[a]; Plca; protein disulfide isomerase associated 3; protein disulfide isomerase family A member 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide-iso
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2923
Content And Storage:
-20°C
Form:
Liquid
Antigen: mGluR5
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P31424, P41594, Q3UVX5
Gene Symbols: Grm5
Immunogen: Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone: S75-33
Conjugate: Unconjugated
Gene: Grm5
Gene Alias: 6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 108071, 24418, 2915
Content And Storage: -20°C
Form: Liquid
Antigen:
mGluR5
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P31424, P41594, Q3UVX5
Gene Symbols:
Grm5
Immunogen:
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone:
S75-33
Conjugate:
Unconjugated
Gene:
Grm5
Gene Alias:
6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
108071, 24418, 2915
Content And Storage:
-20°C
Form:
Liquid
Antigen: mGluR5
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P31424, P41594, Q3UVX5
Gene Symbols: Grm5
Immunogen: Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone: S75-3
Conjugate: Unconjugated
Gene: Grm5
Gene Alias: 6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 108071, 24418, 2915
Content And Storage: -20°C
Form: Liquid
Antigen:
mGluR5
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P31424, P41594, Q3UVX5
Gene Symbols:
Grm5
Immunogen:
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone:
S75-3
Conjugate:
Unconjugated
Gene:
Grm5
Gene Alias:
6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
108071, 24418, 2915
Content And Storage:
-20°C
Form:
Liquid