PIMA527703

GABRA1 Monoclonal Antibody (N95/35), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527703-Each-of-1 In Stock ₹ 50,180.94

PIMA527703 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

GABRA1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.

P14867, P62812, P62813

Gene Symbols

GABRA1

Immunogen

Fusion protein amino acids 355-394 of human GABA-A-R-Alpha1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

N95/35

Conjugate

Unconjugated

Gene

GABRA1

Gene Alias

ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

14394, 2554, 29705

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA527700

--

Img

Thermo Scientific

PIMA527699

--

Img

Thermo Scientific

PIMA527702

--

Img

Thermo Scientific

PIMA527701

--

Img

Thermo Scientific

PIMA527696

--

Img

Thermo Scientific

PIMA527947

--

Img

Thermo Scientific

PIMA527724

--

Img

Thermo Scientific

PIMA528331

--

Description

  • 1 μg/mL of MA5-27703 was sufficient for detection of alpha1 GABA receptor in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 55kDa
  • No cross-reactivity against GABA-A-R-Alpha 2 or -Alpha3
  • Gamma -aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA Receptor (GABAA-R) subtype
  • GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse
  • The GABAA-R is a multimeric subunit complex
  • To date aix alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified
  • Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-R sensitive to GABA
  • However, coexpression of a gamma-subunit is required for benzodiazepine modulation
  • The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor
  • Lastly, phosphorylation of beta-subunits of the receptor has been shown to modulate GABAA-R function.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527703

--


Antigen:
GABRA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P14867, P62812, P62813

Gene Symbols:
GABRA1

Immunogen:
Fusion protein amino acids 355-394 of human GABA-A-R-Alpha1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
N95/35

Conjugate:
Unconjugated

Gene:
GABRA1

Gene Alias:
ECA4, EIEE19, EJM, EJM5, GABA alpha subunit, GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, GABAA alpha 1, GABAAR alpha1, GABRA 1, GABRA1, Gabra-1, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1, gamma-aminobutyric acid A receptor alpha 1 variant 1, gamma-aminobutyric acid A receptor alpha 1 variant 2, gamma-aminobutyric acid A receptor alpha 1 variant 3, gamma-aminobutyric acid A receptor alpha 1 variant 4, gamma-aminobutyric acid A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, gamma-aminobutyric acid receptor subunit alpha-1-like, gamma-aminobutyric acid type A receptor alpha1 subunit, gamma-aminobutyric acid type A receptor subunit alpha1, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14394, 2554, 29705

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527705

--


Antigen:
FGF13

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P70377, Q92913, Q9ERW3

Gene Symbols:
FGF13

Immunogen:
Synthetic peptide amino acids 2-18 (AAAIASSLIRQKRQARE) of human FHF2A. 100% identical to rat, 94% identical to mouse. >80% identity with FGF12A/FHF1A, FGF14A/FHF4A and FGF11A/FHF3A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S235-22

Conjugate:
Unconjugated

Gene:
FGF13

Gene Alias:
AFGF; ECGF; ECGFA; ECGFB; FGF; FGF 1; FGF alpha; FGF13; FGF-13; FGF13A; FGF2; FGFA; Fhf2; FHF-2; Fibroblast growth factor; fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; GLIO703; HBGF 1; HBGF1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14168, 2258, 84488

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527706

--


Antigen:
HSPB8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9EPX0, Q9JK92, Q9UJY1

Gene Symbols:
HSPB8

Immunogen:
Full-length his-tagged human recombinant HSP22

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3C12-H11

Conjugate:
Unconjugated

Gene:
HSPB8

Gene Alias:
Alpha-crystallin C chain; AU018630; AW413033; CMT2L; Cryac; crystallin, alpha C; D5Ucla4; DHMN 2; DHMN2; E2IG1; E2-induced gene 1 protein; H11; H11K; heat shock 22kDa protein 8; heat shock 27kDa protein 8; Heat shock protein; heat shock protein 8; heat shock protein B8; heat shock protein beta-8; heat shock protein family B (small) member 8; HMN 2; HMN2; HMN2A; HSB8; HSP; HSP20-like; Hsp22; HSPB 8; Hspb8; OTTHUMP00000239768; PP1629; Protein kinase H11; small stress protein-like protein HSP22

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
113906, 26353, 80888

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527708

--


Antigen:
CRYAB

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P02510, P02511, P23927, P23928, Q7M2W6

Gene Symbols:
Cryab

Immunogen:
Native Human Alpha B Crystallin

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
1A7.D5

Conjugate:
Unconjugated

Gene:
Cryab

Gene Alias:
2310001E10Rik; 3526402H21Rik; AACRYA; active transcription factor CREB; alpha B-crystallin; alpha crystallin B; alpha(B)-crystallin; alpha-B-crystallin; Alpha-crystallin B chain; alpha-crystallin B chain-like protein; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CMD1II; CREB; CREB1; CREB-1; Crya2; Crya-2; CRYAB; CryAB antibody; crystallin alpha B; crystallin, alpha 2; crystallin, alpha B; crystallin, alpha polypeptide 2; CTPP2; CTRCT16; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; epididymis secretory protein Li 101; heat shock protein beta-5; heat shock protein CryAB; heat shock protein HspB5; heat-shock 20 kD like-protein; HEL-S-101; HSPB5; HspB5 protein; MFM2; P23; Renal carcinoma antigen NY-REN-27; rosenthal fiber component; transactivator protein; Y protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100519789, 12955, 1410, 25420, 281719

Content And Storage:
-20°C

Form:
Liquid