PIMA527947

CD49d (Integrin alpha 4) Recombinant Rabbit Monoclonal Antibody (RM268), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527947-Each-of-1 In Stock ₹ 47,956.38

PIMA527947 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

CD49d (Integrin alpha 4)

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P13612, Q00651

Gene Symbols

ITGA4

Immunogen

A peptide corresponding to the C-terminus of human Integrin alpha 4 (ITGA4)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM268

Conjugate

Unconjugated

Gene

ITGA4

Gene Alias

269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16401, 311144, 3676

Content And Storage

-20°C

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
  • Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
  • Alpha4 chain associates with either beta1 or beta7 chain
  • It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
  • These ligands included Madcam, VCAM, and fibronectin
  • Madcam is known as the principal ligand for integrin alpha4beta7
  • Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

Compare Similar Items

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Img

Thermo Scientific

PIMA527947

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Antigen:
CD49d (Integrin alpha 4)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P13612, Q00651

Gene Symbols:
ITGA4

Immunogen:
A peptide corresponding to the C-terminus of human Integrin alpha 4 (ITGA4)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM268

Conjugate:
Unconjugated

Gene:
ITGA4

Gene Alias:
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16401, 311144, 3676

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527948

--


Antigen:
JAM-A (CD321)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q9Y624

Gene Symbols:
F11r

Immunogen:
A peptide corresponding to the N-terminus of human human JAM1 (Junctional adhesion molecule 1)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM275

Conjugate:
Unconjugated

Gene:
F11r

Gene Alias:
9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11R; JAM; JAM1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; platelet F11 receptor; UNQ264/PRO301

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
50848

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527972

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Antigen:
MyD88

Classification:
Recombinant Monoclonal

Concentration:
0.05 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q99836

Gene Symbols:
MYD88

Immunogen:
A peptide corresponding to the N-terminus of human MyD88

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM306

Conjugate:
Unconjugated

Gene:
MYD88

Gene Alias:
mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4615

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527973

--


Antigen:
p27Kip1

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P46414, P46527

Gene Symbols:
Cdkn1b

Immunogen:
A peptide corresponding to the C-terminus of human p27Kip1

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM302

Conjugate:
Unconjugated

Gene:
Cdkn1b

Gene Alias:
AA408329; AI843786; Cdki1b; CDKN1B; CDKN4; CDN1B; cyclin dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B (p27 Kip1); Cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor p27 Kip1; cyclin-dependent kinase inhibitor p27/Kip1; KIP1; MEN1B; MEN4; p27; P27 CDKN1B; p27(KIP1); p27Kip1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1027, 12576

Content And Storage:
-20°C

Form:
Liquid