PIMA528213

DLL4 (delta-like 4) Monoclonal Antibody (HMD4-2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528213-Each-of-1 In Stock ₹ 48,469.74

PIMA528213 - Each of 1

₹ 48,469.74

In Stock

Quantity

1

Base Price: ₹ 48,469.74

GST (18%): ₹ 8,724.553

Total Price: ₹ 57,194.293

Antigen

DLL4 (delta-like 4)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q9JI71

Gene Symbols

Dll4

Immunogen

Recombinant mouse DLL4

Quantity

250μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone

HMD4-2

Conjugate

Unconjugated

Gene

Dll4

Gene Alias

AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341

Host Species

Hamster

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

54485

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Hamster anti Mouse Delta-Like Protein 4 antibody, clone HMD4-2 recognizes mouse Delta-like protein 4 (DLL4), one of the five major ligands of the Notch signalling pathway, which is activated through the binding of specific ligands to the Notch receptors Notch 1-4
  • Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1
  • DLL4 is expressed in the vasculature and plays a critical role in vascular development
  • It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network
  • DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation
  • This in turn leads to a decrease in tumor growth, with no apparent toxicity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA528213

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Antigen:
DLL4 (delta-like 4)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9JI71

Gene Symbols:
Dll4

Immunogen:
Recombinant mouse DLL4

Quantity:
250μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
HMD4-2

Conjugate:
Unconjugated

Gene:
Dll4

Gene Alias:
AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341

Host Species:
Hamster

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54485

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA528215

--


Antigen:
SIRP gamma

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9P1W8

Gene Symbols:
SIRPG

Immunogen:
Purified recombinant SIRPgammaCD4

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
OX-119

Conjugate:
FITC

Gene:
SIRPG

Gene Alias:
bA77C3.1; CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal regulatory protein gamma; signal-regulatory protein beta 2; signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRPB2; SIRP-B2; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55423

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA528216

--


Antigen:
SIRP gamma

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide

Gene Accession No.:
Q9P1W8

Gene Symbols:
SIRPG

Immunogen:
Purified recombinant SIRPgammaCD4

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
OX-119

Conjugate:
PE

Gene:
SIRPG

Gene Alias:
bA77C3.1; CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal regulatory protein gamma; signal-regulatory protein beta 2; signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRPB2; SIRP-B2; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
55423

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Lyophilized

Img

Thermo Scientific

PIMA528217

--


Antigen:
SIRP gamma

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9P1W8

Gene Symbols:
SIRPG

Immunogen:
Purified recombinant SIRP gamma CD4

Quantity:
200μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
OX-119

Conjugate:
Unconjugated

Gene:
SIRPG

Gene Alias:
bA77C3.1; CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal regulatory protein gamma; signal-regulatory protein beta 2; signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRPB2; SIRP-B2; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
55423

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid