PIMA528625

DLL4 (delta-like 4) Monoclonal Antibody (MHD4-46), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528625-Each-of-1 In Stock ₹ 13,236.13

PIMA528625 - Each of 1

₹ 13,236.13

In Stock

Quantity

1

Base Price: ₹ 13,236.13

GST (18%): ₹ 2,382.503

Total Price: ₹ 15,618.633

Antigen

DLL4 (delta-like 4)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

Q9NR61

Gene Symbols

Dll4

Immunogen

recombinant soluble human DLL4

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Functional Assay

Clone

MHD4-46

Conjugate

Unconjugated

Gene

Dll4

Gene Alias

AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

54567

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development
  • Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 μm filter sterilized
  • Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test
  • Functional Application: Blocking
  • Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1
  • DLL4 is expressed in the vasculature and plays a critical role in vascular development
  • It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network
  • DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation
  • This in turn leads to a decrease in tumor growth, with no apparent toxicity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA528625

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Antigen:
DLL4 (delta-like 4)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
Q9NR61

Gene Symbols:
Dll4

Immunogen:
recombinant soluble human DLL4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Functional Assay

Clone:
MHD4-46

Conjugate:
Unconjugated

Gene:
Dll4

Gene Alias:
AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54567

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA528626

--


Antigen:
WBP1L

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
Q9NX94

Gene Symbols:
WBP1L

Immunogen:
Recombinant fragment of human OPAL1 (amino acids 152-342)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
OPAL1-01

Conjugate:
PE

Gene:
WBP1L

Gene Alias:
C10orf26; OPA1L; OPAL1; Outcome predictor in acute leukemia 1; WBP1L; WW domain binding protein 1-like

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54838

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA528627

--


Antigen:
WBP1L

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 15mM sodium azide; pH 8

Gene Accession No.:
Q9NX94

Gene Symbols:
WBP1L

Immunogen:
Recombinant fragment of human OPAL1 (amino acids 152-342)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Western Blot

Clone:
OPAL1-01

Conjugate:
Unconjugated

Gene:
WBP1L

Gene Alias:
C10orf26; OPA1L; OPAL1; Outcome predictor in acute leukemia 1; WBP1L; WW domain binding protein 1-like

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54838

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA528628

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Antigen:
DDIT4L

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
Q96D03

Gene Symbols:
DDIT4L

Immunogen:
human DDIT4L (amino acids 2-98, N-terminal)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
DDIT-03

Conjugate:
PE

Gene:
DDIT4L

Gene Alias:
1700037B15Rik; 1700108M02Rik; Ddit4l; DNA damage inducible transcript 4 like; DNA damage-inducible transcript 4-like protein; DNA-damage-inducible transcript 4-like; DNA-damage-inducible transcript 4-like protein; DNA-damage-inducible transcript 4-like protein-like; HIF-1 responsive protein RTP801-like; homolog of mouse SMHS1; protein regulated in development and DNA damage response 2; REDD2; REDD-2; regulated in development and DNA damage response 2; RTP801L; skeletal muscle hindlimb suspension 1; Smhs1; Soleus muscle atrophied after hindlimb suspension protein 1

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
115265

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid