PIMA528273

CD11a/CD18 Monoclonal Antibody (CVS9), PE, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528273-Each-of-1 In Stock ₹ 64,127.22

PIMA528273 - Each of 1

₹ 64,127.22

In Stock

Quantity

1

Base Price: ₹ 64,127.22

GST (18%): ₹ 11,542.90

Total Price: ₹ 75,670.12

Antigen

CD11a/CD18

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

PBS with 1% BSA, 5% sucrose and 0.09% sodium azide

Gene Accession No.

0

Gene Symbols

ITGAL, ITGB2

Immunogen

Equine leucocytes

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Equine

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry

Clone

CVS9

Conjugate

PE

Gene

ITGAL

Gene Alias

antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; CD11 antigen-like family member A; CD11a; CD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; Complement receptor C3 subunit beta; integrin alpha L; integrin alpha-L; integrin beta chain, beta 2; integrin beta-2; integrin gene promoter; integrin subunit alpha L; integrin subunit beta 2; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGAL; ITGB2; LAD; LCAMB; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte cell adhesion molecule CD18; leukocyte function-associated molecule 1 alpha chain; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; MAC-1; MF17; MFI7

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100056128, 100065508

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Lyophilized

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Description

  • Mouse anti Horse CD11a/CD18 antibody, clone CVS9 recognizes the equine homolog of the human CD11a/CD18 cell surface antigen, a hetrodimer expressed on all equine cells of haemopoietic origin
  • CD11/CD18 (LFA-1) are beta 2-type integrins
  • The leukocyte integrins are a family of heterodimeric receptors that mediate divalent cation-dependent cellular adhesion reactions
  • T cells use integrins in essentially all of their functions
  • Integrins become active following signalling through other membrane receptors, which cause both affinity alteration and an increase in integrin clustering
  • The monoclonal antibody 24 recognizes a structural feature and is strictly dependent upon the presence of Mg2+
  • The epitope is located within, or in close proximity to, the three conserved cation binding domains and therefore a measure of Mg2+ bound to the leukocyte integrins and thus reflects functionally active molecules
  • The epitope can be induced on polymorphonuclear leukocytes and on monocytes
  • Glu173 and Glu175 of the beta(2) I domain are identified as critical for antibody 24 binding
  • The monoclonal antibody 24 inhibits monocyte-dependent, antigen specific T cell proliferation and IL-2- activated natural killer cell assays
  • The antibody does not interfere with mitogen-stimulated T cell proliferation
  • Furthermore the monoclonal antibody 24 prevents deadhesion of receptor/ligand pairs, possible locking leukocyte integrins in an active conformation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA528273

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Antigen:
CD11a/CD18

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
ITGAL, ITGB2

Immunogen:
Equine leucocytes

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Equine

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
CVS9

Conjugate:
PE

Gene:
ITGAL

Gene Alias:
antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; CD11 antigen-like family member A; CD11a; CD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; Complement receptor C3 subunit beta; integrin alpha L; integrin alpha-L; integrin beta chain, beta 2; integrin beta-2; integrin gene promoter; integrin subunit alpha L; integrin subunit beta 2; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGAL; ITGB2; LAD; LCAMB; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte cell adhesion molecule CD18; leukocyte function-associated molecule 1 alpha chain; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; MAC-1; MF17; MFI7

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100056128, 100065508

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Lyophilized

Img

Thermo Scientific

PIMA528274

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Antigen:
CD11b

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
ITGAM

Immunogen:
__

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Bovine

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry

Clone:
CC126

Conjugate:
FITC

Gene:
ITGAM

Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
407124

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA528275

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Antigen:
CD11b

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
ITGAM

Immunogen:
__

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Bovine

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
CC126

Conjugate:
Unconjugated

Gene:
ITGAM

Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
407124

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA528276

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Antigen:
CD11c

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
Itgax

Immunogen:
Cells from multiple species

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Bovine

Product Type:
Antibody

Isotype:
IgM

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
BAQ153A

Conjugate:
Unconjugated

Gene:
Itgax

Gene Alias:
AI449405; CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; Cr4; integrin alpha X; integrin alpha-X; integrin aX; integrin subunit alpha X; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Itgax; Leu M5; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain; RGD1561123; SLEB6

Host Species:
Mouse

Purification Method:
Nan

Regulatory Status:
RUO

Gene ID (Entrez):
100298252

Content And Storage:
4° C, do not freeze

Form:
Liquid