CD18a Monoclonal Antibody (PNK-I), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528305-Each-of-1 | In Stock | ₹ 43,849.50 |
PIMA528305 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,849.50
GST (18%): ₹ 7,892.91
Total Price: ₹ 51,742.41
Antigen
CD18a
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P53714
Gene Symbols
ITGB2
Immunogen
Porcine large granular lymphocytes
Quantity
100μg
Primary or Secondary
Primary
Target Species
Porcine
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation
Clone
PNK-I
Conjugate
Unconjugated
Gene
ITGB2
Gene Alias
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
396943
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Mouse anti Pig CD18a, clone PNK-I recognizes porcine CD18a
- CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes
- CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling
- CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18)
- In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts
- Absence of CD18 leads to leukocyte adhesion deficiency-1, severe reduction of CD18 expression leads to the development of a psoriasiform skin disease
- CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis
- Defects in the CD18 gene are the cause of leukocyte adhesion deficiency type I (LAD1)
- Two transcript variants encoding the CD18 protein have been identified.
Compare Similar Items
Show Difference
Antigen: CD18a
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P53714
Gene Symbols: ITGB2
Immunogen: Porcine large granular lymphocytes
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Porcine
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Functional Assay, Immunoprecipitation
Clone: PNK-I
Conjugate: Unconjugated
Gene: ITGB2
Gene Alias: 2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 396943
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen: CD1w2
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: CD1A
Immunogen: __
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Bovine
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry
Clone: CC20
Conjugate: PE
Gene: CD1A
Gene Alias: CD1A; CD1a molecule; T-cell surface glycoprotein CD1a
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 781011
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Lyophilized
Antigen: CD2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: CD2
Immunogen: __
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Bovine
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: CC42
Conjugate: Unconjugated
Gene: CD2
Gene Alias: Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 497022
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
