PIMA528596

CD62P (P-Selectin) Monoclonal Antibody (AK4), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528596-Each-of-1 In Stock ₹ 24,085.14

PIMA528596 - Each of 1

₹ 24,085.14

In Stock

Quantity

1

Base Price: ₹ 24,085.14

GST (18%): ₹ 4,335.325

Total Price: ₹ 28,420.465

Antigen

CD62P (P-Selectin)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P16109

Gene Symbols

SELP

Immunogen

Human platelets

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Chimpanzee, Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

AK4

Conjugate

Biotin

Gene

SELP

Gene Alias

CD62; CD62 antigen-like family member P; CD62P; CD62P antigen; CD62P; CD62 homolog; FLJ45155; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; Grmp; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; PSELECT; P-selectin; P-selectin precursor; RP1-86F14.2; selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); selectin, platelet; Selp

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6403, 736004

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • The antibody AK4 recognizes CD62P (P-selectin), a 140 kD single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes; it is relocated to the plasma membrane upon activation
  • P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling
  • P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets
  • From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate
  • P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes
  • P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes
  • P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, thrombosis and tissue destruction
  • Clinically, P-selectin is used to distinguish heparin induced thrombocytopenia with and without thrombosis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA528596

--


Antigen:
CD62P (P-Selectin)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P16109

Gene Symbols:
SELP

Immunogen:
Human platelets

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chimpanzee, Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
AK4

Conjugate:
Biotin

Gene:
SELP

Gene Alias:
CD62; CD62 antigen-like family member P; CD62P; CD62P antigen; CD62P; CD62 homolog; FLJ45155; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; Grmp; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; PSELECT; P-selectin; P-selectin precursor; RP1-86F14.2; selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); selectin, platelet; Selp

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6403, 736004

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA528597

--


Antigen:
CD43

Classification:
Monoclonal

Concentration:
__

Formulation:
TBS with 0.2% BSA and 15mM sodium azide; pH 8

Gene Accession No.:
P16150

Gene Symbols:
SPN

Immunogen:
Human T lymphocytes.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
MEM-59

Conjugate:
Alexa Fluor 700

Gene:
SPN

Gene Alias:
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6693

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA528598

--


Antigen:
TCR V beta 5.3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
0

Gene Symbols:
TRB

Immunogen:
Human thymoma cell line HPB-ALL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation, Western Blot

Clone:
MEM-262

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA528599

--


Antigen:
CD71 (Transferrin Receptor)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P02786

Gene Symbols:
TFRC

Immunogen:
NALM-6 human pre-B cell line

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
MEM-75

Conjugate:
Alexa Fluor 700

Gene:
TFRC

Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7037

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid