PIMA528597

CD43 Monoclonal Antibody (MEM-59), Alexa Fluor™ 700, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528597-Each-of-1 In Stock ₹ 35,678.52

PIMA528597 - Each of 1

₹ 35,678.52

In Stock

Quantity

1

Base Price: ₹ 35,678.52

GST (18%): ₹ 6,422.134

Total Price: ₹ 42,100.654

Antigen

CD43

Classification

Monoclonal

Conjugate

Alexa Fluor 700

Gene

SPN

Gene Alias

3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6693

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

MEM-59

Formulation

TBS with 0.2% BSA and 15mM sodium azide; pH 8

Gene Accession No.

P16150

Gene Symbols

SPN

Immunogen

Human T lymphocytes.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • The antibody MEM-59 recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin), a 95-135 kDa type I transmembrane glycoprotein (mucin-type) which is involved in lymphocyte activation
  • CD43 is expressed by platelets and at high levels on the surface of all leukocytes; it is negative on resting B lymphocytes and erythrocytes
  • Recommended dilution is for 100 μL of whole blood or 1x10^6 cells in suspension
  • CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells
  • CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation
  • By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic
  • CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors
  • Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promotes tumor proliferation and viability
  • CD43 appears to be an important modulator of leukocyte functions
  • Diseases associated with CD43 dysfunction include Wiscott-Aldrich Syndrome and Adenoid Basal Cell Carcinoma.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA528597

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Antigen:
CD43

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene:
SPN

Gene Alias:
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6693

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-59

Formulation:
TBS with 0.2% BSA and 15mM sodium azide; pH 8

Gene Accession No.:
P16150

Gene Symbols:
SPN

Immunogen:
Human T lymphocytes.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

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PIMA528598

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Antigen:
TCR V beta 5.3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
TRB

Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6957

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation, Western Blot

Clone:
MEM-262

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
0

Gene Symbols:
TRB

Immunogen:
Human thymoma cell line HPB-ALL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

PIMA528599

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Antigen:
CD71 (Transferrin Receptor)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene:
TFRC

Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7037

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-75

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P02786

Gene Symbols:
TFRC

Immunogen:
NALM-6 human pre-B cell line

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

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PIMA528600

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Antigen:
CD120a (TNF Receptor I)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Tnfrsf1a

Gene Alias:
CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7132

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
H398

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P19438

Gene Symbols:
Tnfrsf1a

Immunogen:
Recombinant full length human CD120a

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a