PIMA528600

CD120a (TNF Receptor I) Monoclonal Antibody (H398), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528600-Each-of-1 In Stock ₹ 16,761.20

PIMA528600 - Each of 1

₹ 16,761.20

In Stock

Quantity

1

Base Price: ₹ 16,761.20

GST (18%): ₹ 3,017.016

Total Price: ₹ 19,778.216

Antigen

CD120a (TNF Receptor I)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

P19438

Gene Symbols

Tnfrsf1a

Immunogen

Recombinant full length human CD120a

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

H398

Conjugate

Unconjugated

Gene

Tnfrsf1a

Gene Alias

CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7132

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • The mouse monoclonal antibody H398 recognizes the extracellular domain of CD120a, a 55 kDa receptor for tumor necrosis factor
  • The antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta
  • Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 μm filter sterilized
  • Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test
  • Functional Application: Blocking
  • TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors
  • TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression
  • The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1)
  • In humans, the TNFR1 gene is located on chromosome 12
  • Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor
  • Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal dominant periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.

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Show Difference

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PIMA528600

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Antigen:
CD120a (TNF Receptor I)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P19438

Gene Symbols:
Tnfrsf1a

Immunogen:
Recombinant full length human CD120a

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
H398

Conjugate:
Unconjugated

Gene:
Tnfrsf1a

Gene Alias:
CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7132

Content And Storage:
4° C, do not freeze

Form:
Liquid

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Antigen:
Vimentin

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P08670

Gene Symbols:
Vim

Immunogen:
Human vimentin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
VI-RE/1

Conjugate:
APC

Gene:
Vim

Gene Alias:
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7431

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

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Antigen:
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Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with no preservative; pH 8.0

Gene Accession No.:
O43508

Gene Symbols:
Tnfsf12

Immunogen:
human CD255-transfected 2PK-3 cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry

Clone:
CARL-1

Conjugate:
Unconjugated

Gene:
Tnfsf12

Gene Alias:
APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8742

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

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PIMA528605

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Antigen:
TWEAK

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
O43508

Gene Symbols:
Tnfsf12

Immunogen:
human CD255-transfected 2PK-3 cells

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry

Clone:
CARL-1

Conjugate:
PE

Gene:
Tnfsf12

Gene Alias:
APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8742

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid