PIMA529606
TRAIL-R2 (DR5) Recombinant Rabbit Monoclonal Antibody (102), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA529606-Each-of-1 | In Stock | ₹ 39,785.40 |
PIMA529606 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,785.40
GST (18%): ₹ 7,161.372
Total Price: ₹ 46,946.772
Antigen
TRAIL-R2 (DR5)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
O14763
Gene Symbols
TNFRSF10B
Immunogen
Recombinant Human CD262 protein (Met1-Glu182)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Flow Cytometry
Clone
102
Conjugate
Unconjugated
Gene
TNFRSF10B
Gene Alias
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
8795
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human TNFRSF10B/TRAILR2/CD262/DR5
- DR5 (Apo2, TRAIL-R2, TRICK2, KILLER) is a recently identified death domain containing receptor for TRAIL, which mediates TRAIL induced apoptosis
- DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain
- DR5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal
- Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by DR5
- Two transcript variants encoding different isoforms of DR5 and one non-coding transcript have been found
- Overexpression of DR5 induces apoptosis and activates NF-kappa-B
- DR5 is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen
- Diseases associated with DR5 dysfunction include squamous cell carcinoma, and diffuse infiltrative lymphocytosis syndrome.
Compare Similar Items
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Antigen: TRAIL-R2 (DR5)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O14763
Gene Symbols: TNFRSF10B
Immunogen: Recombinant Human CD262 protein (Met1-Glu182)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Flow Cytometry
Clone: 102
Conjugate: Unconjugated
Gene: TNFRSF10B
Gene Alias: apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8795
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TRAIL-R2 (DR5)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O14763
Gene Symbols:
TNFRSF10B
Immunogen:
Recombinant Human CD262 protein (Met1-Glu182)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Flow Cytometry
Clone:
102
Conjugate:
Unconjugated
Gene:
TNFRSF10B
Gene Alias:
apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; Dr5; dr-5; Fas-like protein; KILLER; KILLER/DR5; KILLER/DR5 TRAIL death-inducing receptor; Ly98; MK; p53-regulated DNA damage-inducible cell death receptor(killer); sCD262; soluble CD262; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; UNQ160/PRO186; ZTNFR9
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8795
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD264 (TRAIL-R4)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9UBN6
Gene Symbols: TNFRSF10D
Immunogen: Recombinant Human TRAIL R4/CD264/TNFRSF10D Protein (Met1-His211)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 2F8B1
Conjugate: Unconjugated
Gene: TNFRSF10D
Gene Alias: CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8793
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD264 (TRAIL-R4)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9UBN6
Gene Symbols:
TNFRSF10D
Immunogen:
Recombinant Human TRAIL R4/CD264/TNFRSF10D Protein (Met1-His211)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
2F8B1
Conjugate:
Unconjugated
Gene:
TNFRSF10D
Gene Alias:
CD264; DCR2; Decoy receptor 2; TNF receptor superfamily member 10d; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; TRAILR4; TRAIL-R4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; UNQ251/PRO288
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8793
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD254 (RANK Ligand)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O14788
Gene Symbols: TNFSF11
Immunogen: Recombinant Human RANKL/OPGL/TNFSF11/CD254 Protein (Gly 63-Asp 244)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 218
Conjugate: Unconjugated
Gene: TNFSF11
Gene Alias: CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8600
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD254 (RANK Ligand)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O14788
Gene Symbols:
TNFSF11
Immunogen:
Recombinant Human RANKL/OPGL/TNFSF11/CD254 Protein (Gly 63-Asp 244)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
218
Conjugate:
Unconjugated
Gene:
TNFSF11
Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8600
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TPH1
Classification: Recombinant Monoclonal
Concentration: 5.0 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P17752
Gene Symbols: TPH1
Immunogen: Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein (Ile2-Ile444)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: 145
Conjugate: Unconjugated
Gene: TPH1
Gene Alias: indoleacetic acid-5-hydroxylase; L-tryptophan hydroxylase; MGC119994; TPH; Tph1; TPH2; TPRH; TRPH; tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1; tryptophan hydroxylase; tryptophan hydroxylase (tryptophan 5-monooxygenase); tryptophan hydroxylase 1; tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7166
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TPH1
Classification:
Recombinant Monoclonal
Concentration:
5.0 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P17752
Gene Symbols:
TPH1
Immunogen:
Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein (Ile2-Ile444)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
145
Conjugate:
Unconjugated
Gene:
TPH1
Gene Alias:
indoleacetic acid-5-hydroxylase; L-tryptophan hydroxylase; MGC119994; TPH; Tph1; TPH2; TPRH; TRPH; tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1; tryptophan hydroxylase; tryptophan hydroxylase (tryptophan 5-monooxygenase); tryptophan hydroxylase 1; tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7166
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid