PIMA529415
CD146 Recombinant Rabbit Monoclonal Antibody (44), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA529415-Each-of-1 | In Stock | ₹ 41,368.26 |
PIMA529415 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,368.26
GST (18%): ₹ 7,446.287
Total Price: ₹ 48,814.547
Antigen
CD146
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P43121
Gene Symbols
MCAM
Immunogen
Recombinant Human CD146 protein (Met1-Gly559)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
44
Conjugate
Unconjugated
Gene
MCAM
Gene Alias
1-gicerin; AV025631; CD146; CD149; Cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; l-gicerin; l-gicerin precursor; l-gicerin protein; LOW QUALITY PROTEIN: cell surface glycoprotein MUC18; MCAM; melanoma adhesion molecule; melanoma cell adhesion molecule; Melanoma-associated antigen A32; melanoma-associated antigen MUC18; Muc18; mucin-18; s-endo; S-endo 1 endothelial-associated antigen; s-gicerin; s-gicerin precursor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4162
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human CD146/MCAM
- CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily
- CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and malignant cell types
- In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly
- CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue
- CD146 expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread
- Further, CD146 could be an adhesion molecule active in neural crest cells during embryonic development
- CD146 acts also as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Compare Similar Items
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Antigen: CD146
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P43121
Gene Symbols: MCAM
Immunogen: Recombinant Human CD146 protein (Met1-Gly559)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 44
Conjugate: Unconjugated
Gene: MCAM
Gene Alias: 1-gicerin; AV025631; CD146; CD149; Cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; l-gicerin; l-gicerin precursor; l-gicerin protein; LOW QUALITY PROTEIN: cell surface glycoprotein MUC18; MCAM; melanoma adhesion molecule; melanoma cell adhesion molecule; Melanoma-associated antigen A32; melanoma-associated antigen MUC18; Muc18; mucin-18; s-endo; S-endo 1 endothelial-associated antigen; s-gicerin; s-gicerin precursor
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4162
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD146
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P43121
Gene Symbols:
MCAM
Immunogen:
Recombinant Human CD146 protein (Met1-Gly559)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
44
Conjugate:
Unconjugated
Gene:
MCAM
Gene Alias:
1-gicerin; AV025631; CD146; CD149; Cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; l-gicerin; l-gicerin precursor; l-gicerin protein; LOW QUALITY PROTEIN: cell surface glycoprotein MUC18; MCAM; melanoma adhesion molecule; melanoma cell adhesion molecule; Melanoma-associated antigen A32; melanoma-associated antigen MUC18; Muc18; mucin-18; s-endo; S-endo 1 endothelial-associated antigen; s-gicerin; s-gicerin precursor
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4162
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MESDC2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q14696
Gene Symbols: Mesd
Immunogen: Recombinant Human MESDC2 protein (Ala34-Lys230)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 502
Conjugate: Unconjugated
Gene: Mesd
Gene Alias: 2210015O11Rik; AW537813; BOCA; KIAA0081; LDLR chaperone MESD; LRP chaperone MESD; MESD; Mesdc2; MESDM; mesoderm development candiate 2; mesoderm development candidate 2; Mesoderm development LRP chaperone MESD; Mesoderm development protein; mKIAA0081; msd; renal carcinoma antigen NY-REN-61; UNQ1911/PRO4369
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23184
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MESDC2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q14696
Gene Symbols:
Mesd
Immunogen:
Recombinant Human MESDC2 protein (Ala34-Lys230)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
502
Conjugate:
Unconjugated
Gene:
Mesd
Gene Alias:
2210015O11Rik; AW537813; BOCA; KIAA0081; LDLR chaperone MESD; LRP chaperone MESD; MESD; Mesdc2; MESDM; mesoderm development candiate 2; mesoderm development candidate 2; Mesoderm development LRP chaperone MESD; Mesoderm development protein; mKIAA0081; msd; renal carcinoma antigen NY-REN-61; UNQ1911/PRO4369
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23184
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: c-Met
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P08581
Gene Symbols: MET
Immunogen: Recombinant Human c-MET/HGFR protein (Met1-Thr932)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Flow Cytometry
Clone: 243
Conjugate: Unconjugated
Gene: MET
Gene Alias: AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4233
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
c-Met
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P08581
Gene Symbols:
MET
Immunogen:
Recombinant Human c-MET/HGFR protein (Met1-Thr932)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Flow Cytometry
Clone:
243
Conjugate:
Unconjugated
Gene:
MET
Gene Alias:
AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4233
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: METAP2
Classification: Monoclonal
Concentration: __
Formulation: PBS with no preservative
Gene Accession No.: P50579
Gene Symbols: METAP2
Immunogen: Recombinant Human MAP2 Protein (Met1-Tyr478)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 09
Conjugate: Unconjugated
Gene: METAP2
Gene Alias: 4930584B20Rik; A930035J23Rik; AI047573; AL024412; Amp2; AU014659; eIF-2-associated p67; eIF-2-associated p67 homolog; initiation factor 2 associated 67 kDa protein; initiation factor 2-associated 67 kDa glycoprotein; initiation factor 2-associated protein (p67); MAP 2; MAP2; metAP 2; Metap2; Methionine aminopeptidase 2; methionyl aminopeptidase 2; Mnpep; p67; p67eIF2; Peptidase M; peptidase M 2; similar to methionyl aminopeptidase 2; testicular tissue protein Li 17
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 10988
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
METAP2
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with no preservative
Gene Accession No.:
P50579
Gene Symbols:
METAP2
Immunogen:
Recombinant Human MAP2 Protein (Met1-Tyr478)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
09
Conjugate:
Unconjugated
Gene:
METAP2
Gene Alias:
4930584B20Rik; A930035J23Rik; AI047573; AL024412; Amp2; AU014659; eIF-2-associated p67; eIF-2-associated p67 homolog; initiation factor 2 associated 67 kDa protein; initiation factor 2-associated 67 kDa glycoprotein; initiation factor 2-associated protein (p67); MAP 2; MAP2; metAP 2; Metap2; Methionine aminopeptidase 2; methionyl aminopeptidase 2; Mnpep; p67; p67eIF2; Peptidase M; peptidase M 2; similar to methionyl aminopeptidase 2; testicular tissue protein Li 17
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
10988
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid