PIMA529637

USP7 Monoclonal Antibody (03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA529637-Each-of-1 In Stock ₹ 31,229.40

PIMA529637 - Each of 1

₹ 31,229.40

In Stock

Quantity

1

Base Price: ₹ 31,229.40

GST (18%): ₹ 5,621.292

Total Price: ₹ 36,850.692

Antigen

USP7

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q93009

Gene Symbols

USP7

Immunogen

Recombinant Human USP7/HAUSP protein (Lys208-Glu560)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

ELISA, Flow Cytometry, Immunocytochemistry

Clone

03

Conjugate

Unconjugated

Gene

USP7

Gene Alias

2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7874

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA529634

--

Img

Thermo Scientific

PIMA529587

--

Img

Thermo Scientific

PIMA527791

--

Img

Thermo Scientific

PIMA529048

--

Img

Thermo Scientific

PIMA529430

--

Img

Thermo Scientific

PIMA527808

--

Img

Thermo Scientific

PIMA527731

--

Img

Thermo Scientific

PIMA529674

--

Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human USP7/HAUSP
  • USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
  • Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP activity generally stabilizes its substrate proteins
  • HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53
  • Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
  • Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
  • Another important role of HAUSP function involves the oncogenic stabilization of p53
  • Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
  • An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA529637

--


Antigen:
USP7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q93009

Gene Symbols:
USP7

Immunogen:
Recombinant Human USP7/HAUSP protein (Lys208-Glu560)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Flow Cytometry, Immunocytochemistry

Clone:
03

Conjugate:
Unconjugated

Gene:
USP7

Gene Alias:
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7874

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529638

--


Antigen:
VAPB

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O95292

Gene Symbols:
VAPB

Immunogen:
Recombinant Human VAPB/VAP-B Protein (Met1-Pro132)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Clone:
103

Conjugate:
Unconjugated

Gene:
VAPB

Gene Alias:
AI225786; AI840687; AI848259; ALS 8; ALS8; ALS8VAMP-B/VAMP-C; D2Abb2e; R75548; UNQ484/PRO983; vamp; VAMP (vesicle-associated membrane protein)-associated protein B and C; Vamp 33b; VAMP associated protein B and C; VAMP B; VAMP B VAMP C; VAMP B/VAMP C; VAMP C; Vamp33b; VAMP-associated 33 kDa protein; VAMP-associated protein 33b; VAMP-associated protein B; VAMPB; VAMP-B; VAMPB/VAMPC; VAMP-B/VAMP-C; VAMPC; VAMP-C; VAP 33b; VAP B; VAP B/VAP C; VAP C; VAP33b; Vapb; VAP-B; VAPB/VAPC; VAP-B/VAP-C; VAPC; VAP-C; vesicle-associated membrane protein, associated protein B and C; vesicle-associated membrane protein-associated protein B; Vesicle-associated membrane protein-associated protein B/C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9217

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529639

--


Antigen:
VAPB

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O95292

Gene Symbols:
VAPB

Immunogen:
Recombinant Human VAPB/VAP-B protein (Met1-Pro132)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Clone:
208

Conjugate:
Unconjugated

Gene:
VAPB

Gene Alias:
AI225786; AI840687; AI848259; ALS 8; ALS8; ALS8VAMP-B/VAMP-C; D2Abb2e; R75548; UNQ484/PRO983; vamp; VAMP (vesicle-associated membrane protein)-associated protein B and C; Vamp 33b; VAMP associated protein B and C; VAMP B; VAMP B VAMP C; VAMP B/VAMP C; VAMP C; Vamp33b; VAMP-associated 33 kDa protein; VAMP-associated protein 33b; VAMP-associated protein B; VAMPB; VAMP-B; VAMPB/VAMPC; VAMP-B/VAMP-C; VAMPC; VAMP-C; VAP 33b; VAP B; VAP B/VAP C; VAP C; VAP33b; Vapb; VAP-B; VAPB/VAPC; VAP-B/VAP-C; VAPC; VAP-C; vesicle-associated membrane protein, associated protein B and C; vesicle-associated membrane protein-associated protein B; Vesicle-associated membrane protein-associated protein B/C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9217

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529643

--


Antigen:
VISTA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9H7M9

Gene Symbols:
VSIR

Immunogen:
Recombinant Human VISTA/GI24/B7-H5 Protein (Met1-Ala194)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
027

Conjugate:
Unconjugated

Gene:
VSIR

Gene Alias:
4632428N05Rik; B7H5; B7-H5; C10orf54; C1H10orf54; C28H10orf54; C4H10orf54; chromosome 10 open reading frame 54; DD1alpha; Death Domain1alpha; Dies1; differentiation of ESCs 1; GI24; PD-1H; PDCD1 homolog; PD-H1; platelet receptor Gi24; PP2135; RIKEN cDNA 4632428N05 gene; SISP1; sisp-1; Stress-induced secreted protein-1; UNQ730/PRO1412; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; V-type immunoglobulin domain-containing suppressor of T-cell activation

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64115

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid