PIMA531970

CD107b (LAMP-2) Recombinant Rabbit Monoclonal Antibody (SA46-01), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531970-Each-of-1 In Stock ₹ 45,646.26

PIMA531970 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

CD107b (LAMP-2)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P13473, P17046, P17047

Gene Symbols

LAMP2

Immunogen

Synthetic peptide within Human LAMP2a aa 361-410

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Clone

SA46-01

Conjugate

Unconjugated

Gene

LAMP2

Gene Alias

CD107 antigen-like family member B, CD107b, EGK_20887, Igp96, Lamp II, LAMP2, LAMP-2, LAMP-2 Isoform 2A, LAMP-2 Variant A, Lamp-2a, Lamp-2b, Lamp-2c, LAMPB, LGP110, LGP-110, LGP-96, LGP-B, lysosomal associated membrane protein 2, lysosomal membrane glycoprotein 2, lysosomal membrane glycoprotein type B, lysosomal-associated membrane protein 2, lysosome-associated membrane glycoprotein 2, lysosome-associated membrane protein 2, Mac3, RP23-193O17.2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16784, 24944, 3920

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins
  • LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome
  • Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide
  • Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa
  • LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
  • LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy
  • LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
  • The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C
  • LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane
  • The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation
  • LAMP2 deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danon’s disease).

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Img

Thermo Scientific

PIMA531970

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Antigen:
CD107b (LAMP-2)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P13473, P17046, P17047

Gene Symbols:
LAMP2

Immunogen:
Synthetic peptide within Human LAMP2a aa 361-410

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
SA46-01

Conjugate:
Unconjugated

Gene:
LAMP2

Gene Alias:
CD107 antigen-like family member B, CD107b, EGK_20887, Igp96, Lamp II, LAMP2, LAMP-2, LAMP-2 Isoform 2A, LAMP-2 Variant A, Lamp-2a, Lamp-2b, Lamp-2c, LAMPB, LGP110, LGP-110, LGP-96, LGP-B, lysosomal associated membrane protein 2, lysosomal membrane glycoprotein 2, lysosomal membrane glycoprotein type B, lysosomal-associated membrane protein 2, lysosome-associated membrane glycoprotein 2, lysosome-associated membrane protein 2, Mac3, RP23-193O17.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16784, 24944, 3920

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531971

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Antigen:
MLKL

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q8NB16, Q9D2Y4

Gene Symbols:
Mlkl

Immunogen:
Recombinant protein within Human MLKL aa 333-471

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
SA40-04

Conjugate:
Unconjugated

Gene:
Mlkl

Gene Alias:
9130019I15Rik, hMLKL, mixed lineage kinase domain like pseudokinase, mixed lineage kinase domain-like, mixed lineage kinase domain-like protein, Mlkl, rCG51567-like

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
197259, 74568

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531972

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Antigen:
ALAS1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P13196

Gene Symbols:
ALAS1

Immunogen:
Recombinant protein within Human Alas1 aa 510-640

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
SA70-04

Conjugate:
Unconjugated

Gene:
ALAS1

Gene Alias:
5'-aminolevulinate synthase 1, 5-aminolevulinate synthase 1, 5-aminolevulinate synthase, nonspecific, mitochondrial, 5-aminolevulinic acid synthase 1, ALAS, ALA-S, ALAS1, Alas-1, ALAS3, ALASH, Alas-h, ALAS-N, aminolevulinate synthase H, aminolevulinate, delta-, synthase 1, aminolevulinic acid synthase 1, delta-ALA synthase 1, delta-ALA synthetase, delta-aminolevulinate synthase 1, MIG4, migration-inducing protein 4, OK/SW-cl.121, succinyl-CoA: glycine C-succinyl transferase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
211

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531975

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Antigen:
Filamin A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P21333, Q8BTM8

Gene Symbols:
Flna

Immunogen:
Synthetic peptide within Human Filamin A aa 2,598-2,647

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SA30-08

Conjugate:
Unconjugated

Gene:
Flna

Gene Alias:
450 kDa protein, ABP-280, ABPX, actin binding protein 280, actin-binding protein 280, alpha filamin, alpha-filamin, CSBS, CVD1, dilated pupils 2, Dilp2, Endothelial actin-binding protein, Endothelial actin-binding protein 280), F730004A14Rik, filamin, filamin 1, filamin A, filamin A, alpha, filamin, alpha, Filamin1, filamin-1, FilaminA, Filamin-A, FLN, FLN1, Flna, FLN-A, FMD, GENA 379, gizzard filamin, MNS, NHBP, Non-muscle filamin, OPD, OPD1, OPD2, RGD1560614, XLVD, XMVD

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
192176, 2316, 293860

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid