PIMA532235

WAVE2 Recombinant Rabbit Monoclonal Antibody (SC66-05), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532235-Each-of-1 In Stock ₹ 45,646.26

PIMA532235 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

WAVE2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q8BH43, Q9Y6W5

Gene Symbols

WASF2

Immunogen

Synthetic peptide within Human WASF2 aa 440-485

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Clone

SC66-05

Conjugate

Unconjugated

Gene

WASF2

Gene Alias

AW742646, D4Ertd13e, dJ393P12.2, IMD2, protein WAVE-2, putative Wiskott-Aldrich syndrome protein family member 4, SCAR2, suppressor of cyclic-AMP receptor (WASP-family), verprolin homology domain-containing protein 2, WAS protein family member 2, WAS protein family, member 2, Wasf2, WASF4, WASP family protein member 2, WASP family protein member 4, WASP family Verprolin-homologous protein 2, WAVE2, Wiskott-Aldrich syndrome protein family member 2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10163, 242687, 313024

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization
  • The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the actin cytoskeleton
  • The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases
  • The two protein homologs WAVE1 and WAVE2 specifically regulate membrane ruffling by inducing the formation of actin filament clusters in response to GTP binding and activating Rac
  • The WAVE proteins mediate this actin polymerization by cooperating with the Arp2/3 complex, a nucleation core, and thereby promoting the formation of actin filaments
  • WAVE1, which is also designated SCAR (for suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed with the expression highest in peripheral blood leukocytes
  • WAVE3 forms a multiprotein complex that links receptor kinases and actin
  • Binding to actin occurs through a C-terminal verprolin homology domain in all family members
  • The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532235

--


Antigen:
WAVE2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q8BH43, Q9Y6W5

Gene Symbols:
WASF2

Immunogen:
Synthetic peptide within Human WASF2 aa 440-485

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
SC66-05

Conjugate:
Unconjugated

Gene:
WASF2

Gene Alias:
AW742646, D4Ertd13e, dJ393P12.2, IMD2, protein WAVE-2, putative Wiskott-Aldrich syndrome protein family member 4, SCAR2, suppressor of cyclic-AMP receptor (WASP-family), verprolin homology domain-containing protein 2, WAS protein family member 2, WAS protein family, member 2, Wasf2, WASF4, WASP family protein member 2, WASP family protein member 4, WASP family Verprolin-homologous protein 2, WAVE2, Wiskott-Aldrich syndrome protein family member 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10163, 242687, 313024

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532236

--


Antigen:
DAXX

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9UER7

Gene Symbols:
DAXX

Immunogen:
Recombinant protein within Human Daxx aa 195-313

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
SC54-06

Conjugate:
Unconjugated

Gene:
DAXX

Gene Alias:
BING2, CENP-C binding protein, DADB-159G18.9, DAP6, Daxx, death domain associated protein, Death domain-associated protein 6, death-associated protein 6, death-domain associated protein, EAP1, ETS1-associated protein 1, Fas death domain-associated protein, Fas-binding protein, hDaxx, MGC126245, MGC126246, SMIM40, Unknown (protein for MGC:138055)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532237

--


Antigen:
MEKK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q61083, Q9Y2U5

Gene Symbols:
Map3k2

Immunogen:
Synthetic peptide within Human MEKK2 aa 1-47

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC68-02

Conjugate:
Unconjugated

Gene:
Map3k2

Gene Alias:
2.7.11.25, 9630061B06Rik, AI585793, MAP/ERK kinase kinase 2, MAP3K2, MAPK/ERK kinase kinase 2, MAPKKK2, MEK kinase 2, MEKK 2, MEKK2, MEKK2B, mitogen activated protein kinase kinase kinase 2, mitogen-activated protein kinase kinase kinase 2, protein kinase MEKK2b

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10746, 171492, 26405

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532239

--


Antigen:
MTCO2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P00403, P35354

Gene Symbols:
COX2, MT-CO2

Immunogen:
Synthetic peptide within Human MTCO2 aa 199-227

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC06-88

Conjugate:
Unconjugated

Gene:
MT-CO2

Gene Alias:
ACI60_gp02, Co2, COII, COX2, COXII, cyclooxygenase, cytchrome c oxidase sububnit 2, Cytochrome c oxidase polypeptide II, Cytochrome c oxidase subunit 2, cytochrome c oxidase subunit II, mitochondrially encoded cytochrome c oxidase II, Mtco2, MT-CO2, OXI1, OXII, Q0250

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4513

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid