PIMA532018

HP1 alpha Recombinant Rabbit Monoclonal Antibody (SR44-03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532018-Each-of-1 In Stock ₹ 44,619.54

PIMA532018 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

HP1 alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P45973, Q61686

Gene Symbols

Cbx5

Immunogen

Recombinant protein within Human HP1 alpha aa 101-191

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SR44-03

Conjugate

Unconjugated

Gene

Cbx5

Gene Alias

2610029O15Rik, antigen p25, C75991, Cbx5, Cbx5 antibody, chromobox 5, chromobox homolog 5, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, chromobox-like protein 5, epididymis luminal protein 25, HEL25, heterochromatin protein 1 alpha, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha, HGNC:1555, HP1, HP1 alpha, HP-1 alpha antibody, HP1 alpha homolog, Hp1a, Hp1alpha, HP1-ALPHA, HP1Hs alpha, HP1Hs-alpha, mHP1(alpha)

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12419, 23468, 300266

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
  • It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
  • High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
  • Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
  • In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532018

--


Antigen:
HP1 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P45973, Q61686

Gene Symbols:
Cbx5

Immunogen:
Recombinant protein within Human HP1 alpha aa 101-191

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SR44-03

Conjugate:
Unconjugated

Gene:
Cbx5

Gene Alias:
2610029O15Rik, antigen p25, C75991, Cbx5, Cbx5 antibody, chromobox 5, chromobox homolog 5, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, chromobox-like protein 5, epididymis luminal protein 25, HEL25, heterochromatin protein 1 alpha, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha, HGNC:1555, HP1, HP1 alpha, HP-1 alpha antibody, HP1 alpha homolog, Hp1a, Hp1alpha, HP1-ALPHA, HP1Hs alpha, HP1Hs-alpha, mHP1(alpha)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12419, 23468, 300266

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532019

--


Antigen:
ARPC5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O15511, Q4KLF8, Q9CPW4

Gene Symbols:
ARPC5

Immunogen:
Synthetic peptide within Human p16 ARC aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SR34-02

Conjugate:
Unconjugated

Gene:
ARPC5

Gene Alias:
5830443F10Rik, actin related protein 2/3 complex subunit 5, actin related protein 2/3 complex subunit 5, 16kDa, actin related protein 2/3 complex, subunit 5, actin related protein 2/3 complex, subunit 5, 16kDa, actin-related protein 2/3 complex subunit 5, actin-related protein 2/3 complex subunit 5-like protein, ARC16, Arp2/3 complex 16 kDa subunit, Arp2/3 protein complex subunit p16, Arpc5, dJ127C7.3, p16-ARC

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10092, 360854, 67771

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532021

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Antigen:
Phospho-EIF2S1 (Ser51)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P05198, P68101, Q6ZWX6

Gene Symbols:
EIF2S1

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser51 of human eIF-2a

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SZ01-06

Conjugate:
Unconjugated

Gene:
EIF2S1

Gene Alias:
0910001O23Rik, 2410026C18Rik, 35kDa, EIF2, EIF-2, eIF2 alpha, eIF2 alpha subunit, EIF2A, eIF-2A, eIF2alpha, EIF-2alpha, eIF-2-alpha, EIF2S1, eif2s1b, Eukaryotic translation initiation factor 2 subunit 1, eukaryotic translation initiation factor 2 subunit 1b, eukaryotic translation initiation factor 2 subunit alpha, eukaryotic translation initiation factor 2, subunit 1 alpha, eukaryotic translation initiation factor 2, subunit 1 alpha b, eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa, eukaryotic translation initiation factor 2A, fb19d01, translation initiation factor subunit, wu:fb19d01

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13665, 1965, 54318

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532022

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Antigen:
ATF2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P15336, P16951

Gene Symbols:
Atf2

Immunogen:
Synthetic peptide within Human ATF2 aa 456-505

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SZ17-01

Conjugate:
Unconjugated

Gene:
Atf2

Gene Alias:
Activating 2, Activating transcription factor 2, activating transcription factor 2 splice variant ATF2-var2, ATF2, Atf-2, cAMP response element-binding protein CRE-BP1, cAMP responsive element binding protein 2, formerly, cAMP-dependent transcription factor ATF-2, CREB2, CREB-2, CRE-BP, CREBP1, CRE-BP1, Cyclic AMP-dependent transcription factor ATF-2, cyclic AMP-responsive element-binding protein 2, D130078H02Rik, D18875, HB16, Histone acetyltransferase ATF2, MGC111558, mXBP, MXBP protein, OTTHUMP00000205345, OTTHUMP00000205347, OTTHUMP00000205348, OTTHUMP00000205350, OTTHUMP00000205352, OTTHUMP00000205353, OTTHUMP00000205354, Tg(Gzma-Klra1)7Wum, TREB7

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11909, 1386

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid