PIMA532024

Phospho-ERK1/ERK2 (Thr202,Thr185) Recombinant Rabbit Monoclonal Antibody (SZ2-4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532024-Each-of-1 In Stock ₹ 45,646.26

PIMA532024 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Phospho-ERK1/ERK2 (Thr202,Thr185)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P27361, P28482

Gene Symbols

MAPK1, MAPK3

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Thr185 of human Erk2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SZ2-4

Conjugate

Unconjugated

Gene

MAPK1

Gene Alias

12559, 9030612K14Rik, AA407128, AU018647, BcDNA:RE08694, C78273, CG12559, CG12559-PA, CG12559-PC, CG12559-PD, CG12559-PE, CG12559-PG, CG12559-PH, CG12559-PI, CG18732, CT34260, CT39192, DERK, D-ERK, DERK-A, Diphospho-ERK, dm-dpERK, Dmel\CG12559, Dmel_CG12559, DmErk, DmERKA, DmERK-A, DmMAPK, dpERK, dp-ERK, dpERK1, dpMAPK, drosophila ERK, Dsor2, E(sina)7, EC2-1, EK2-1, enhancer of seven in absentia 7, ERK, Erk MAP kinase, Erk/Map kinase, ERK/rolled, Erk1, Erk-1, erk1 erk2, Erk1/2, ERK1b, ERK2, ERK-2, ERKA, ERK-A, ERT1, ERT2, Esrk1, extracellular signal-regulated kinase, extracellular signal-regulated kinase (ERK2), extracellular signal-regulated kinase 1, Extracellular signal-regulated kinase 2, extracellular signal-regulated kinase A, extracellular signal-regulated kinase-1, extracellular signal-regulated kinase-2, extracellular signal-related kinase 1, Extracellular-regulated kinase A, extracellular-signal-regulated kinase 2, Extracellular-signal-related kinase A, EY2-2, fi06b09, GroupI

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5594, 5595

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells
  • Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways
  • When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine/threonine protein kinase and activates it as well
  • Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2
  • Upon activation, the ERKs either phosphorylate a number of cytoplasmic targets or migrate to the nucleus, where they phosphorylate and activate a number of transcription factors such as c-Fos and Elk-1.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532024

--


Antigen:
Phospho-ERK1/ERK2 (Thr202,Thr185)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P27361, P28482

Gene Symbols:
MAPK1, MAPK3

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Thr185 of human Erk2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SZ2-4

Conjugate:
Unconjugated

Gene:
MAPK1

Gene Alias:
12559, 9030612K14Rik, AA407128, AU018647, BcDNA:RE08694, C78273, CG12559, CG12559-PA, CG12559-PC, CG12559-PD, CG12559-PE, CG12559-PG, CG12559-PH, CG12559-PI, CG18732, CT34260, CT39192, DERK, D-ERK, DERK-A, Diphospho-ERK, dm-dpERK, Dmel\CG12559, Dmel_CG12559, DmErk, DmERKA, DmERK-A, DmMAPK, dpERK, dp-ERK, dpERK1, dpMAPK, drosophila ERK, Dsor2, E(sina)7, EC2-1, EK2-1, enhancer of seven in absentia 7, ERK, Erk MAP kinase, Erk/Map kinase, ERK/rolled, Erk1, Erk-1, erk1 erk2, Erk1/2, ERK1b, ERK2, ERK-2, ERKA, ERK-A, ERT1, ERT2, Esrk1, extracellular signal-regulated kinase, extracellular signal-regulated kinase (ERK2), extracellular signal-regulated kinase 1, Extracellular signal-regulated kinase 2, extracellular signal-regulated kinase A, extracellular signal-regulated kinase-1, extracellular signal-regulated kinase-2, extracellular signal-related kinase 1, Extracellular-regulated kinase A, extracellular-signal-regulated kinase 2, Extracellular-signal-related kinase A, EY2-2, fi06b09, GroupI

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5594, 5595

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532025

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Antigen:
ERK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P28482, P63085, P63086

Gene Symbols:
MAPK1

Immunogen:
Synthetic peptide within Human ERK2 aa 311-360

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SZ25-01

Conjugate:
Unconjugated

Gene:
MAPK1

Gene Alias:
9030612K14Rik, AA407128, AU018647, C78273, ERK, ERK2, ERK-2, ERT1, extracellular signal-regulated kinase 2, extracellular signal-regulated kinase-2, extracellular-signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, Mapk, MAPK 1, MAPK 2, Mapk1, MAPK2, mitogen activated protein kinase 1, mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, p38, p40, p41, p41mapk, P42MAPK, p42-MAPK, Prkm1, PRKM2, protein tyrosine kinase ERK2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
116590, 26413, 5594

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532027

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Antigen:
pro-Caspase 3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P42574, P70677

Gene Symbols:
CASP3

Immunogen:
Synthetic peptide within Human pro Caspase-3 aa 18-67

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SZ02-08

Conjugate:
Unconjugated

Gene:
CASP3

Gene Alias:
A830040C14Rik, AC-3, Apopain, Casp3, CASP-3, caspase 3, caspase 3, apoptosis related cysteine protease, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease, caspase-3, Caspase-3 subunit p12, Caspase-3 subunit p17, CC3, Cpp32, CPP-32, CPP32B, cysteine protease CPP32, LICE, mLdy, PARP cleavage protease, procaspase3, protein Yama, SCA-1, SREBP cleavage activity 1, Yama

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12367, 836

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532029

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Antigen:
BCL-XL

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P53563, Q07817, Q64373

Gene Symbols:
BCL2L1

Immunogen:
Synthetic peptide within Human Bcl-XL aa 37-86

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SZ3-03

Conjugate:
Unconjugated

Gene:
BCL2L1

Gene Alias:
anti-apoptosis regulatory protein, apoptosis regulator Bcl-X, B cell lymphoma 2 like, B cell lymphoma like X, B-cell leukemia/lymphoma x, Bcl(X)L, BCL2 like 1, Bcl2l, BCL2L1, bcl2-L-1, BCL2-like 1, Bcl-2-like protein 1, BCLX, bcl-x, BCLXL, Bcl-XL, BCL-XL/S, BCLXS, bcl-xS, Blc2l, DKFZp781P2092, EGK_02534, OTTHUMP00000030550, OTTHUMP00000030552, OTTHUMP00000030555, OTTHUMP00000030556, OTTHUMP00000030557, PPP1R52, protein phosphatase 1, regulatory subunit 52, RP5-857M17.3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12048, 24888, 598

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid