PIMA532027
pro-Caspase 3 Recombinant Rabbit Monoclonal Antibody (SZ02-08), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532027-Each-of-1 | In Stock | ₹ 44,619.54 |
PIMA532027 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
pro-Caspase 3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P42574, P70677
Gene Symbols
CASP3
Immunogen
Synthetic peptide within Human pro Caspase-3 aa 18-67
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SZ02-08
Conjugate
Unconjugated
Gene
CASP3
Gene Alias
A830040C14Rik, AC-3, Apopain, Casp3, CASP-3, caspase 3, caspase 3, apoptosis related cysteine protease, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease, caspase-3, Caspase-3 subunit p12, Caspase-3 subunit p17, CC3, Cpp32, CPP-32, CPP32B, cysteine protease CPP32, LICE, mLdy, PARP cleavage protease, procaspase3, protein Yama, SCA-1, SREBP cleavage activity 1, Yama
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12367, 836
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis
- The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits
- The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions
- All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme
- Gene for Caspase-3 also known as Yama, CPP32, and apopain codes for a 32-kDa protein
- Caspase-3 cleaves the death substrate poly(ADP-ribose) polymerase (PARP) to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein
- Other Caspase-3 substrates include DNA-PK, actin, GAS2, and procaspase-6, etc
- Caspase-3 is activated by cleavage events at Asp-28/Ser-29 (between N-terminal pro-domain) and Asp-175/Ser-176 (between large and small subunits) to generate a large subunit of 17-kDa and a small subunit of 12-kDa.
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Antigen: pro-Caspase 3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P42574, P70677
Gene Symbols: CASP3
Immunogen: Synthetic peptide within Human pro Caspase-3 aa 18-67
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SZ02-08
Conjugate: Unconjugated
Gene: CASP3
Gene Alias: A830040C14Rik, AC-3, Apopain, Casp3, CASP-3, caspase 3, caspase 3, apoptosis related cysteine protease, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease, caspase-3, Caspase-3 subunit p12, Caspase-3 subunit p17, CC3, Cpp32, CPP-32, CPP32B, cysteine protease CPP32, LICE, mLdy, PARP cleavage protease, procaspase3, protein Yama, SCA-1, SREBP cleavage activity 1, Yama
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12367, 836
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
pro-Caspase 3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P42574, P70677
Gene Symbols:
CASP3
Immunogen:
Synthetic peptide within Human pro Caspase-3 aa 18-67
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SZ02-08
Conjugate:
Unconjugated
Gene:
CASP3
Gene Alias:
A830040C14Rik, AC-3, Apopain, Casp3, CASP-3, caspase 3, caspase 3, apoptosis related cysteine protease, caspase 3, apoptosis-related cysteine peptidase, caspase 3, apoptosis-related cysteine protease, caspase-3, Caspase-3 subunit p12, Caspase-3 subunit p17, CC3, Cpp32, CPP-32, CPP32B, cysteine protease CPP32, LICE, mLdy, PARP cleavage protease, procaspase3, protein Yama, SCA-1, SREBP cleavage activity 1, Yama
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12367, 836
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: BCL-XL
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P53563, Q07817, Q64373
Gene Symbols: BCL2L1
Immunogen: Synthetic peptide within Human Bcl-XL aa 37-86
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SZ3-03
Conjugate: Unconjugated
Gene: BCL2L1
Gene Alias: anti-apoptosis regulatory protein, apoptosis regulator Bcl-X, B cell lymphoma 2 like, B cell lymphoma like X, B-cell leukemia/lymphoma x, Bcl(X)L, BCL2 like 1, Bcl2l, BCL2L1, bcl2-L-1, BCL2-like 1, Bcl-2-like protein 1, BCLX, bcl-x, BCLXL, Bcl-XL, BCL-XL/S, BCLXS, bcl-xS, Blc2l, DKFZp781P2092, EGK_02534, OTTHUMP00000030550, OTTHUMP00000030552, OTTHUMP00000030555, OTTHUMP00000030556, OTTHUMP00000030557, PPP1R52, protein phosphatase 1, regulatory subunit 52, RP5-857M17.3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12048, 24888, 598
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
BCL-XL
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P53563, Q07817, Q64373
Gene Symbols:
BCL2L1
Immunogen:
Synthetic peptide within Human Bcl-XL aa 37-86
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SZ3-03
Conjugate:
Unconjugated
Gene:
BCL2L1
Gene Alias:
anti-apoptosis regulatory protein, apoptosis regulator Bcl-X, B cell lymphoma 2 like, B cell lymphoma like X, B-cell leukemia/lymphoma x, Bcl(X)L, BCL2 like 1, Bcl2l, BCL2L1, bcl2-L-1, BCL2-like 1, Bcl-2-like protein 1, BCLX, bcl-x, BCLXL, Bcl-XL, BCL-XL/S, BCLXS, bcl-xS, Blc2l, DKFZp781P2092, EGK_02534, OTTHUMP00000030550, OTTHUMP00000030552, OTTHUMP00000030555, OTTHUMP00000030556, OTTHUMP00000030557, PPP1R52, protein phosphatase 1, regulatory subunit 52, RP5-857M17.3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12048, 24888, 598
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Bax
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q07812, Q07813, Q63690
Gene Symbols: BAX
Immunogen: Synthetic peptide within Human Bax aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Clone: SZ3-07
Conjugate: Unconjugated
Gene: BAX
Gene Alias: apoptosis regulator BAX, Apoptosis regulator Bcl-X, Bax, Bax zeta, BAX-ALPHA, Bax-alpha protein, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, BCL2 associated X protein, BCL2 associated X, apoptosis regulator, BCL2 like 1, BCL2-associated protein, Bcl-2-associated protein Bax, Bcl2-associated protein Bax, Bcl-2-associated X protein, BCL2-associated X protein, BCL2-associated X protein omega, BCL2L, BCL2L1, Bcl2-L-1, BCL2L4, Bcl2-L-4, BCL2-like 1, bcl-2-like protein 1, Bcl-2-like protein 4, BCLX, Bcl-X, BCL-XL/S, PPP1R52, protein phosphatase 1, regulatory subunit 52
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12028, 24887, 581
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Bax
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q07812, Q07813, Q63690
Gene Symbols:
BAX
Immunogen:
Synthetic peptide within Human Bax aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunohistochemistry, Western Blot
Clone:
SZ3-07
Conjugate:
Unconjugated
Gene:
BAX
Gene Alias:
apoptosis regulator BAX, Apoptosis regulator Bcl-X, Bax, Bax zeta, BAX-ALPHA, Bax-alpha protein, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, BCL2 associated X protein, BCL2 associated X, apoptosis regulator, BCL2 like 1, BCL2-associated protein, Bcl-2-associated protein Bax, Bcl2-associated protein Bax, Bcl-2-associated X protein, BCL2-associated X protein, BCL2-associated X protein omega, BCL2L, BCL2L1, Bcl2-L-1, BCL2L4, Bcl2-L-4, BCL2-like 1, bcl-2-like protein 1, Bcl-2-like protein 4, BCLX, Bcl-X, BCL-XL/S, PPP1R52, protein phosphatase 1, regulatory subunit 52
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12028, 24887, 581
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-Myb (Ser11)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P10242
Gene Symbols: MYB
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser11 of human V-Myb+C-Myb
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SZ04-81
Conjugate: Unconjugated
Gene: MYB
Gene Alias: AI550390, Cmyb, c-myb, cmyb protein, c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, gag-myb protein, M16449, MYB, myb proto-oncogene protein, MYB proto-oncogene, transcription factor, Mybl2, myb-related protein B, myeloblastosis oncogene, myeloblastosis oncogene-like 2, myeloblastosis proto-oncogene product, oncogene AMV, proto-oncogene c-Myb, RP1-32B1.1, transcription factor cmyb, transcriptional activator Myb, tumor-specific myb protein, v-myb avian myeloblastosis viral oncogene homolog
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4602
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-Myb (Ser11)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P10242
Gene Symbols:
MYB
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser11 of human V-Myb+C-Myb
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SZ04-81
Conjugate:
Unconjugated
Gene:
MYB
Gene Alias:
AI550390, Cmyb, c-myb, cmyb protein, c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, gag-myb protein, M16449, MYB, myb proto-oncogene protein, MYB proto-oncogene, transcription factor, Mybl2, myb-related protein B, myeloblastosis oncogene, myeloblastosis oncogene-like 2, myeloblastosis proto-oncogene product, oncogene AMV, proto-oncogene c-Myb, RP1-32B1.1, transcription factor cmyb, transcriptional activator Myb, tumor-specific myb protein, v-myb avian myeloblastosis viral oncogene homolog
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4602
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid