PIMA532257
Caspase 9 Recombinant Rabbit Monoclonal Antibody (SC65-05), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532257-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA532257 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
Caspase 9
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P55211, Q8C3Q9
Gene Symbols
CASP9
Immunogen
Recombinant protein within Human Caspase-9 aa 95-335
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
SC65-05
Conjugate
Unconjugated
Gene
CASP9
Gene Alias
25 kDa caspase-9 dominant negative protein, AI115399, APAF3, APAF-3, apoptotic protease activating factor 3, apoptotic protease MCH-6, Apoptotic protease-activating factor 3, AW493809, cas9, CASP 9, CASP9, CASP-9, Casp9_v1, Casp-9-CTD, caspase 9, caspase 9, apoptosis-related cysteine peptidase, caspase 9, apoptosis-related cysteine protease, Caspase9, caspase-9, caspase-9 dominant negative form, Caspase-9 precursor, Caspase-9 subunit p10, Caspase-9 subunit p35, CASPASE-9c, caspase-9-carboxyl-terminal divergent, CTD, Ice-Lap6, ICE-like apoptotic protease 6, Mch6, OTTHUMP00000002324, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9, RP11-265F14.3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12371, 842
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
- Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
- Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
- Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
- Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
- Caspase 9 is expressed in variety of human tissues
- An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
- Mutations in Caspase 9 affect brain development
- In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
- In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
- Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).
Compare Similar Items
Show Difference
Antigen: Caspase 9
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P55211, Q8C3Q9
Gene Symbols: CASP9
Immunogen: Recombinant protein within Human Caspase-9 aa 95-335
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: SC65-05
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: 25 kDa caspase-9 dominant negative protein, AI115399, APAF3, APAF-3, apoptotic protease activating factor 3, apoptotic protease MCH-6, Apoptotic protease-activating factor 3, AW493809, cas9, CASP 9, CASP9, CASP-9, Casp9_v1, Casp-9-CTD, caspase 9, caspase 9, apoptosis-related cysteine peptidase, caspase 9, apoptosis-related cysteine protease, Caspase9, caspase-9, caspase-9 dominant negative form, Caspase-9 precursor, Caspase-9 subunit p10, Caspase-9 subunit p35, CASPASE-9c, caspase-9-carboxyl-terminal divergent, CTD, Ice-Lap6, ICE-like apoptotic protease 6, Mch6, OTTHUMP00000002324, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9, RP11-265F14.3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12371, 842
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Caspase 9
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P55211, Q8C3Q9
Gene Symbols:
CASP9
Immunogen:
Recombinant protein within Human Caspase-9 aa 95-335
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
SC65-05
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
25 kDa caspase-9 dominant negative protein, AI115399, APAF3, APAF-3, apoptotic protease activating factor 3, apoptotic protease MCH-6, Apoptotic protease-activating factor 3, AW493809, cas9, CASP 9, CASP9, CASP-9, Casp9_v1, Casp-9-CTD, caspase 9, caspase 9, apoptosis-related cysteine peptidase, caspase 9, apoptosis-related cysteine protease, Caspase9, caspase-9, caspase-9 dominant negative form, Caspase-9 precursor, Caspase-9 subunit p10, Caspase-9 subunit p35, CASPASE-9c, caspase-9-carboxyl-terminal divergent, CTD, Ice-Lap6, ICE-like apoptotic protease 6, Mch6, OTTHUMP00000002324, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9, RP11-265F14.3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12371, 842
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: HES1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P35428, Q04666, Q14469
Gene Symbols: HES1
Immunogen: Synthetic peptide within Human Hes1 aa 298-241
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SC06-21
Conjugate: Unconjugated
Gene: HES1
Gene Alias: BHLHB39, class B basic helix-loop-helix protein 39, FLJ20408, Hairy and enhancer of split 1, hairy and enhancer of split 1 (Drosophila), hairy and enhancer of split 1,, hairy homolog, Hairy-like, Hairy-like protein, hes family bHLH transcription factor 1, HES1, Hes-1, hHL, HL, HRY, RHL, transcription factor HES-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 15205, 29577, 3280
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
HES1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P35428, Q04666, Q14469
Gene Symbols:
HES1
Immunogen:
Synthetic peptide within Human Hes1 aa 298-241
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SC06-21
Conjugate:
Unconjugated
Gene:
HES1
Gene Alias:
BHLHB39, class B basic helix-loop-helix protein 39, FLJ20408, Hairy and enhancer of split 1, hairy and enhancer of split 1 (Drosophila), hairy and enhancer of split 1,, hairy homolog, Hairy-like, Hairy-like protein, hes family bHLH transcription factor 1, HES1, Hes-1, hHL, HL, HRY, RHL, transcription factor HES-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
15205, 29577, 3280
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: FNTB
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P49356, Q02293
Gene Symbols: FNTB
Immunogen: Recombinant protein within Human FNTB aa 1-98
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot, Western Blot
Clone: SC06-44
Conjugate: Unconjugated
Gene: FNTB
Gene Alias: 2010013E13Rik, AA409500, CAAX farnesyltransferase subunit beta, EC 2.5.1.58, farnesyl-protein transferase beta-subunit, farnesyltransferase beta subunit, farnesyltransferase, CAAX box, beta, FNTB, FPTB, ft beta, FTase beta, FTase-beta, LOW QUALITY PROTEIN: protein farnesyltransferase subunit beta, protein farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2342, 64511
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
FNTB
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P49356, Q02293
Gene Symbols:
FNTB
Immunogen:
Recombinant protein within Human FNTB aa 1-98
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot, Western Blot
Clone:
SC06-44
Conjugate:
Unconjugated
Gene:
FNTB
Gene Alias:
2010013E13Rik, AA409500, CAAX farnesyltransferase subunit beta, EC 2.5.1.58, farnesyl-protein transferase beta-subunit, farnesyltransferase beta subunit, farnesyltransferase, CAAX box, beta, FNTB, FPTB, ft beta, FTase beta, FTase-beta, LOW QUALITY PROTEIN: protein farnesyltransferase subunit beta, protein farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2342, 64511
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: IkB beta
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q15653
Gene Symbols: NFKBIB
Immunogen: Synthetic peptide within Human IKB beta aa 322-356
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SN0648
Conjugate: Unconjugated
Gene: NFKBIB
Gene Alias: I kappa B beta, I(Kappa)B(beta), ikappaBbeta, I-kappa-B-beta, IkB, IKB B, IKB beta, Ikbb, ikB-B, IkBbeta, ikB-beta, NF kappa BIB, NF-kappa-B inhibitor beta, NF-kappa-BIB, NFKB inhibitor beta, NFKBIB, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta, Thyroid receptor, thyroid receptor-interacting protein 9, TR-interacting protein 9, TRIP 9, TRIP9, TRIP-9
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4793
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IkB beta
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q15653
Gene Symbols:
NFKBIB
Immunogen:
Synthetic peptide within Human IKB beta aa 322-356
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SN0648
Conjugate:
Unconjugated
Gene:
NFKBIB
Gene Alias:
I kappa B beta, I(Kappa)B(beta), ikappaBbeta, I-kappa-B-beta, IkB, IKB B, IKB beta, Ikbb, ikB-B, IkBbeta, ikB-beta, NF kappa BIB, NF-kappa-B inhibitor beta, NF-kappa-BIB, NFKB inhibitor beta, NFKBIB, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta, Thyroid receptor, thyroid receptor-interacting protein 9, TR-interacting protein 9, TRIP 9, TRIP9, TRIP-9
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4793
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid